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Tag: "determines" at biology news

University of Manchester makes made-to-measure skin and bones a reality using inkjet printers

...n as 'tissue scaffolds'. The shape of the scaffold determines theshape of the tissue as it grows. The structures are created by printingvery thin layers of a material repeatedly on top of each other untilthe structure is built. Each layer is just 10 microns thick (1,000layers equals 1cm in thickness).This metho...

UW's Rosetta software to unlock secrets of many human proteins

...roteins with no known function. "Howproteins fold determines how they are structured," said Lars Malmstroemof the UW laboratory that developed the program, "And how they arestructured is related to their function in the body."Because there is an astronomical number of possible conformations for agiven protein,...

Researchers find how protein allows insects to detect and respond to pheromones

...roteins with no known function. "Howproteins fold determines how they are structured," said Lars Malmstroemof the UW laboratory that developed the program, "And how they arestructured is related to their function in the body."Because there is an astronomical number of possible conformations for agiven protein,...

Scientists decipher genome of fungus that can cause life-threatening infections

... from the two strainsmay provide insight into what determines virulence," says BrendanLoftus, a scientist at The Institute for Genomic Research (TIGR) who isthe first author of the Science paper. "Although the two Cryptococcusstrains we examined differ significantly in virulence, we foundsurprisingly little dif...

Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease

... in the packaging. How nature wraps and tags genes determines if and when they become active, according to researchers from Harvard and the Massachusetts Institute of Technology (M.I.T.). They did the largest, most detailed study to date of the protein structure that surrounds the human genome. Their findings ...

Ants Genetic Engineering Leads To Species Interdependency

...raised, rather than a genetic predisposition, that determines whichcaste she will adopt.However, in two harvester ant populations in southern New Mexico,queens and workers from the same colonies are genetically verydifferent; in both species at the site, only the queens are geneticallyderived from a pure specie...

RNA project to create language for scientists worldwide

...ce and humans must be at the software level--which determines how the hardware is used. We are beginning to see that RNA is that software," Leontis said. The possible applications of newly generated knowledge about RNA are vast. RNA science already is playing an important role in understanding normal and abnor...

US life expectancy about to decline, researchers say

...in the New England Journal of Medicine. The study determines that obesity currently reduces life expectancy by approximately four to nine months. "The magnitude of that effect may sound trivial to some, but in fact it's greater than the negative effect of all accidental mortality, such as car accidents, suici...

Insight into natural cholesterol control suggests novel cholesterol-lowering therapy

... functions early in the synthetic process, largely determines the rate of cellular cholesterol production, Debose-Boyd said. When added to intact cells and cellular components in test tubes, lanosterol led other proteins to mark reductase for destruction by attaching a protein called ubiquitin in a process cal...

50-year-old Mystery Solved: Protein Tags Regulate Key Ion Channel

...ss is important because the flow of potassium ions determines whether "excitable" cells in the brain, heart and skeletal muscles "fire," sending out nervous impulses that become thoughts, heartbeats and basketball dunks. "We found that a little-studied process called sumoylation, previously associated with nuc...

Harmful chemicals may reprogram gene response to estrogen

...at a new kind of gene-environment interaction that determines who gets cancer and who doesn't." According to Walker, the increase in frequency and size of the uterine tumors is due to DES' ability to influence estrogen, a female hormone that is involved in promoting the growth of tumors by regulating the activ...

Stanford gut check shows diversity of intestinal ecosystem

...ere surprised at the degree to which an individual determines the particular picture of microbial diversity that we see," said Relman. "Variation between individuals had been suspected, but our data proved to be a dramatic confirmation of this belief." An interesting corollary of this finding is that the abili...

Mother birds increase progesterone to hatch females

In mammals, sperm from the male determines the sex of the offspring. In birds, however, it is the female's sex chromosome that determines offspring sex. Now, Cornell University researchers think they understand the mechanism that several ...

'Smart drug' targets deadly brain cancer

...rotein is a key player in the chain of events that determines drug activity could be useful in screening patients to help determine the best candidates for the drug. Says Dr. Galanis, "This could allow us to customize drug administration to the patients most likely to benefit from it, and in that way, improve c...

Fox Chase study shows that weakened T-cell receptor signals change T-cell lineage

...ha-beta lineage development. "The signal strength determines the level of expression of early growth response (Egr) proteins, with cells choosing the gamma-delta lineage expressing far greater quantities of Egr proteins than those adopting the alpha-beta lineage," explained Wiest. "Egr proteins regulate which ...

Owl genomics presents a HEPATOCHIP for diagnosis of non-alcoholic steatohepatitis

...Marañón Hospital (Madrid). This HEPATOCHIP method determines the co-expression of genes in the liver tissue sample, providing monitoring treatment regimens to check progression/regression of these liver pathologies. This HEPATOCHIP can be used as a prognostic tool for NASH-predisposed patients, to make possib...

U of T researchers map role of Epstein-Barr virus in cancer

...53 is an important protein whose level in the cell determines whether cells will continue to proliferate or stop dividing and die. USP7 is a protein that binds to p53 and makes it stable. Under those conditions, cells stop growing and die, which is a natural state of cell regulation. Once EBNA1 is introduced to...

Study: Well-known protein helps stem cells become secretory cells

...est that this single transcription factor directly determines the amount of secretory activity in a given cell type," said Andrew. ...

Aptamer-based Biosensor screens Air Force personnel and equipment

...as, facilities, and a hand-held "green box," which determines if agents are present. The green box, or DNA Capture Element instrument, was developed by researchers at the Department of Energy's Pacific Northwest National Laboratory. The box uses an Air Force-developed biochemical assay based on aptamers, or sin...

Orientation and the egg

...ast to those who feel that the site of sperm entry determines the orientation of the future body axes. "It would now make sense to base our future experiments on the premise that the mammalian egg neither has nor requires predetermination for successful development," explains Dr. Hiiragi. ...

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