Biologists probe the machinery of cellular protein factories
...tom model of the ribosome. The new picture shows details never seen before and suggests how certain parts o...gth transfer RNAs bound to it. "We can now see the details of most of the interactions between the ribosome, the messenger RNA, and the transfer RNAs," Noller ...Columbia University licenses next-generation DNA sequencing technology
...Sciences (PNAS). This research paper describes the details of the Sequencing by Synthesis Chemistry and how the approach overcomes accuracy limitations of other next generation DNA sequencing systems. It was also recently announced that Columbia University in collaboration with the Waltham, Mass. based Inte...Mayo researchers discover HIV dependence on a human protein
...rapy for HIV or safer methods of gene therapy. The details appear today in the journal Science. "How an incoming virus co-opts the cell's assistance as it proceeds to establish its permanently integrated state is a fascinating question," says Eric Poeschla, M.D., the Mayo Clinic virologist who led the resea...Fast-freeze snapshot yields new picture of nerve-muscle junction
...reeze physical-fixation technique that reveals new details of their location and function in neuromuscular synapses. The technique was used with tiny, one-millimeter-long nematode worms, a lab animal widely studied by neuroscientists. Investigators report the finding in the Aug. 2 issue of the Journal of Ne...A new approach to growing heart muscle
...as the cells organize into tissue. The U-M team details its achievement in a new paper published online in the Journal of Biomedical Materials Research Part A. And while BEHM is still years away from use as a human heart treatment, or as a testing ground for new cardiovascular drugs, the U-M researcher...Memories: It's all in the packaging, scientists say
... a car accident, and yet vividly recall all of the details of a similar experience. In experiments using f...ticular part of the brain that bound the different details together as a package at the time the event occurred. When this brain region wasn't activated to bin...Selecting life: Scientists find new way to search for origin of life
...nal of other techniques can be used to look at the details of the interactions. "What's particularly rewarding about this research is that it's an interdisciplinary effort from different areas of science--biology, chemistry and geology," reflected Hazen. "It marries them to search for an answer to a ques...Cocaine high caused by interference in neuronal receiving stations
... glutamate receptors on neurons, but the molecular details of those effects were unknown. In their experiments, Wang and colleagues first determined that cocaine reduces the activation of glutamate-responsive neurons by affecting a specific component, or subunit, of the receptor, called NR2B. Further exper...Global malaria map key weapon in fight against malaria, scientists say
...In their PLoS Medicine paper, Hay and Snow discuss details and goals of the project, which is funded by the Wellcome Trust, the UK's largest biomedical research charity. The map will be constructed using information from sources such as satellites and population censuses. Statistical approaches will enabl...Protein structure initiative launches new resources for the scientific community
...on. The Knowledgebase also will offer experimental details about each stage of the protein structure determination process, regardless of whether the structure was successfully determined. Information about current PSI proteins being solved will be listed. In addition to searching these details, scientists w...Scientists crack rhino horn riddle
...arply pointed tip. Scientists have discovered new details about the structural materials that form the horn and the role those materials play in the development of the horn's characteristic shape. The horns of most animals have a bony core covered by a thin sheath of keratin, the same substance as hair...Cholera pathogen reveals how bacteria generate energy to live
...nsselaer Polytechnic Institute have discovered new details about how bacteria generate energy to live. In two recently published papers, the scientists add key specifics to the molecular mechanism behind the pathogen that causes cholera. The work could provide a better understanding of this pathogen, while a......n microscope imaging that allowed them to see fine details of the ring structure, and a light microscope method in which specific features glow. Because each method captures different information at a different scale, combining them was tricky, but the two together gave a much more extensive picture than eit...Fruit fly gene research may shed light on human disease processes
..., they can serve as models, allowing us to observe details we can't see in more complex animals." To understand cellular differentiation, Erickson and his graduate students have been researching how fly embryos become male or female, a process that occurs over a 30-minute period early in their development...Common mechanisms for viral DNA replication
...nd to DNA. In addition to describing the molecular details of the DNA–protein interactions and the alterations in protein structure induced by DNA binding, we present a model describing the subsequent assembly events. ...Engineering the heart piece by piece
...tor?that the team uses to grow their BEHM. It also details many other discoveries that have been made by other teams using different cell-growing surfaces and conditions, as well as hurdles that still lie ahead. In all, the authors say, bioengineered cardiac tissue holds immediate promise as a way to study h...Latest advances in DNA sequencing highlighted at DOE Joint Genome Institute User Meeting
... The complete agenda, registration, and other details may be found at: http://www.jgi.doe.gov/meetings/usermtg07/index.html ...Army research mission focused on autism
...couraged to submit proposals. In a few weeks, more details will be available through the CDMRP Web site at h...omposed of scientists and consumer advocates. Full details about the funding offerings will be available in program announcements expected to be released in Ma...Meeting the ethanol challenge: Scientists use supercomputer to target cellulose bottleneck
...ope" that let them zoom in on previously invisible details -- is that initially the binding part of the enzym...y-step process, the scientists can see the precise details of the role of velocity, trajectory, movement, and arm angle. To undertake the large-scale simulatio...New research says winning a Nobel Prize adds nearly 2 years to your lifespan
...e them 528 male scientists with known biographical details (birth and death dates). They looked at one sex only to avoid differences in life span between sexes. They dropped four from that total who died prematurely for non biological reasons - such as active combat in the First World War. That left 524 scie...