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Tag: "details" at biology news

Recombination protein dynamics observed with single monomer resolution

... change in size. The technique revealed intricate details of how RecA nucleates to form a filament, how the filament changes shape, and how the filament removes proteins from DNA. "Contrary to our initial expectations, both ends of the RecA filament continually grow and shrink, but a higher binding rate at...

New light microscope sharpens scientists' focus

... nanometers apart. The scientists published the details of the new technique in the August 10, 2006, edition of Science Express, an advance online publication of the journal Science. The prototype for the new microscope was assembled in September 2005 in the living room of one of the inventors, Hara...

Dissecting the machinery of nicotine's reward

...titut Pasteur and CNRS and colleagues revealed key details of how nicotine stimulates neurons that are an integral part of the reward circuitry. They also found that the same circuitry is involved in triggering exploratory and novelty-seeking behaviors. Their findings bring us a step closer to understanding ...

Scientists take 'snapshots' of enzyme action

...s turnover of the product," Swaminathan says. The details of this process may help scientists understand what happens in cases where compounds are not properly metabolized, and possibly develop corrective measures. One example is a condition called trimethylaminuria, also known as "fish odor syndrome," whi...

Drug dials down the energy within cells, UM researchers find

...properties, the researchers have been studying the details of Bz-423's activity. They learned that the compound targets an enzyme inside mitochondria, the energy factories of cells. The specific enzyme, F1F0-ATPase, is responsible for producing most of the cell's ATP. That's a critical role because ATP, ofte...

K-Staters design and build a low-cost remote sensing tool for environmental studies

...r hour if necessary, we're going to be able to see details that we cannot measure with a regular piloted aircraft. "I think it will be possible not only to be able to say how much and what species of vegetation are there, but more importantly, to know the stress status of the plants: Is there water stress? ...

'Molecular assassin' targets disease gene

...tial of c-Jun as a drug target in inflammation. It details tests in a variety of pre-clinical models showing how effective Dz13 is in problems such as eye disease and arthritis. The next phase in the therapy's development would be a trial, involving up to 10 people with non-melanoma skin cancers. The tumour...

Fire ants: Their true story told by the scientist who loves them

...sort of subterranean family album, "The Fire Ants" details emigration, growth, struggle, development and death in a complex nest of interdependent relationships marked by cooperation, competition and conflict. There's a queen ?sometimes lots of them ?but everybody has a vital role to play. Change is inevitab...

How nature tinkers with the cellular clock

...'s Structural and Computational Biology Unit, "but details of which genes are regulated in this way and the exact timing of their expression have changed a lot throughout evolution. What is really surprising is the speed at which these regulatory systems evolve. We are talking about roughly 100 million years...

USC team reveals structure of APOBEC family protein

...the Apo2 results as a guide, the team revealed new details about how these mutations translate into a loss of AID activity. They showed that some mutations stop AID from folding and therefore working properly, while others block its ability to interact with DNA and RNA molecules. "The x-ray structure of A...

Jefferson researchers uncover new way nature turns genes on and off

... it is conserved in mammals." Understanding the details of the TrxG system could someday have implications for ALL, a dangerous type of childhood leukemia. The disease stems from gene rearrangements in utero. MLL, the gene that is affected in humans, corresponds to Trithorax in fruit flies. "ALL is tho...

Researchers make progress in studying genetic traits of India-born populations

... interested in participating in this study may see details at www.usc.edu/RICADIA ....

A new understanding of how cells defend themselves against bacterial pore-forming toxins

...in increased cell death. "We don't yet know the details of the mechanism by which lipid metabolism leads to cell survival," she says. The lipids are probably used to repair the cell membrane, stopping the potassium leak, which itself can kill the cell, and also protecting the cell from additional toxic su...

'Nymph of the sea' reveals remarkable brood

...d 2 possible juveniles inside, together with other details of her soft part anatomy including legs and eyes. The research team consisted of David Siveter from the University of Leicester, Derek Siveter from Oxford, Mark Sutton from Imperial College London and Derek Briggs from Yale. The team has made a d...

Mars mission Risk 29: Scientists research ways to reduce radiation-induced brain damage

...ns of the irradiated brains to obtain more precise details about the biochemical changes. To date, many scientists have suggested that reduced cognitive impairment results solely from the death of the brain's neurons. Britten believes other, more complex mechanisms are at work, processes that could be mani...

Researchers image molecular motor structural changes

...ctures from the electron microscope images. "Fine details are not apparent unless you remove the extraneous ...e new motor-microtubule models provided structural details of the motor-microtubule interactions that had not been observed previously. The researchers believ...

Quantum dots reviewed -- Could these nanoparticles hold the cure to cancer?

...me imaging and screening of tumours. The level of details provided in this valuable review paper could easily make up a chapter in an expensive text book. However, this paper is available to access free of charge in its entirety at http://www.azonano.com/Details.asp?ArticleID=1726 ...

Altered perception of reward in human cocaine addiction

... disorder of the brain." Goldstein will present details of these studies at a press conference on neuroscience and addiction at the Society for Neuroscience (SfN) annual meeting in Atlanta, Georgia, on Sunday, October 15, 2006, 2 to 3 p.m., and at a SfN symposium on Wednesday, October 18, 8:30 a.m.* Go...

Researchers discover mechanism that determines when detailed memories are retained

...arning and memory, appears to be the key to adding details to a memory. In a study with rats, Norman Weinberg...holine during a learning task correlated with more details of the experience being remembered. The results are the first to tie levels of acetylcholine to memo...

Squid-inspired design could mean better handling of underwater vehicles

...engineering sciences, will present these and other details at the American Geophysical Union's annual fall meeting Dec. 11-15 in San Francisco. A global network of scientists, the AGU describes its mission as the advancement of terrestrial, atmospheric and space research aimed at benefiting humanity. "R...

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