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Tag: "destruction" at biology news

Largest synthetic gene ever built offers insights into anti-malarial drug resistance

... is painting a picture of how the parasite escapes destruction by most of the agents now used against it, he said., When a malaria parasite is transmitted through a mosquito bite, the mosquito injects the parasite into skin or blood, which then travels to the liver within minutes, grows and divides there, a...

Molecule that destroys bone also protects it, new research shows

...e system component that is a primary cause of bone destruction and inflammation in autoimmune diseases such as rh...n the past 18 months to be a primary cause of bone destruction and inflammation in autoimmune diseases. Therapies that target IL-17 or its cellular receptor curren...

Slowing the racing heart

...tudy. Current treatment of arrhythmia requires destruction of tissue surrounding a chaotic pacemaker, followed by insertion of a mechanical pacemaker that can regulate the heartbeat. "Understanding the molecular regulation of the heart's pacemaker opens the possibility of less drastic treatment options, ...

The quest for an effective HIV vaccine presents new possibilities, challenges

...reserves a segment of uninfected CD4+ T cells from destruction benefit the immunized individual" Might people immunized with T-cell vaccines before HIV exposure remain disease-free for a prolonged period once they are infected" Additionally, T-cell vaccines may reduce secondary HIV transmission if they can h...

Rare soft-shell turtle, nesting ground found in Cambodia

... due to its size and edibility, as well as habitat destruction from dams, irrigation and dredging. The stretch of Mekong River where the turtle lives is an area closed for many years to scientific exploration because it was one the last strongholds of the former Khmer Rouge regime in Cambodia. The survey was ...

Investigating the measles virus as a tool to kill multiple myeloma

...xpress a protein, CD46, which allows them to evade destruction by the immune system. Laboratory strains of measles virus seek out this protein and use it as a receptor by which to enter the cancer cells. Upon entry, the virus spreads, infecting nearby tumor cells and fusing them together, increasing cancer cell ...

Glucose triggers brain cell death in rats after hypoglycemic coma

...ycemia –?and cause hypoglycemic coma, resulting in destruction of neurons in the hippocampus and cerebral cortex, which are essential to memory and cognition. "This study tells us for the first time that, in rats, the brain damage occurs not during the coma, but after it, when we give them glucose and their b...

Horse genome assembled

...hat prevent maternal immunological recognition and destruction of the developing fetus during mammalian pregnancy. The research, conducted by Cornell professor Doug Antczak, V.M.D, Ph.D., and funded by the National Institute of Child Health and Human Development, has implications in reproduction, clinical organ ...

Vasectomy may put men at risk for type of dementia

...blems depends on where the disease causes the most destruction in the brain. In FTD, most of the damage is in the frontal lobes; in PPA, it's in the language centers of the left hemisphere of the brain. Weintraub theorizes a vasectomy may raise the risk of PPA (and possibly FTD) because the surgery breeche...

Researchers discover gene crucial for nerve cell insulation

...cular disorder that can be fatal, results from the destruction of myelin in the central nervous system. ...

Large size crucial for Amazon forest reserves

... Many species that occur in intact forest prior to destruction will not be present in a small fragment, but would they be found in an equally small plot surrounded by untouched forest? The answer to this question has profound management implications because it weights the relative importance of area and isolatio...

New species declared: Clouded leopard on Borneo and Sumatra

... needed to obtain better population data. Habitat destruction is the cat’s main threat. The last great forest home of the Bornean Clouded Leopard is the Heart of Borneo, a wild, mountainous region of rainforest the size of Kansas. WWF recently released a report showing that scientists had identified at lea...

Researchers find hepatitis A and hepatitis C attack same protein to block immune defenses

...ne important thing in common: a trick for avoiding destruction by the immune system. Both dodge immune attacks by attacking the same protein ?an essential link in a chain of molecular signals that triggers antiviral responses. "With 30,000-plus proteins in the cell, it’s really remarkable that these two very ...

Researchers hot on the trail of brain cell degeneration

... in cancer formation, also plays a key role in the destruction of neurons in disease. "These surprising findin... different mechanisms. Research has shown that the destruction of cells be over-stimulation depends on excess entry of calcium into the cells. Researchers have lon...

Brain networks strengthened by closing ion channels

...roperly regulated with advancing age, resulting in destruction of cAMP. The dysregulation of the pathway may contribute to increased forgetfulness and susceptibility to distraction as we grow older. The research is also relevant to common disorders such as ADHD, which is associated with weaker regulation of a...

RNAi shows promise in gene therapy, Stanford researcher says

...n which a strand of RNA in the cell can cause the destruction of another strand of RNA that is relaying a protein-coding message from a gene. With that protein-coding message removed, the gene's message is effectively destroyed. When used as gene therapy, RNAi turns off genes that are overactive in such dis...

Statin plus cancer drug deliver combo punch to brain cancer cells

...old under the trade name Mevacor, is known to curb destruction of proteins that put the brakes on cell growth, causing cancer cells to self-destruct through a process called apoptosis. The effects of the statin already is being studied in people at high risk for the deadly skin cancer, melanoma. First extrac...

Experimental vaccine given during pregnancy reduces stillbirths from common virus

...s—proteins that target foreign molecules for later destruction by the immune system. The vaccinated guinea pigs also showed an activity against the virus by their T cells, immune cells critical to the response against disease-causing organisms. Dr. Schleiss said the current paper provides the basis for the p...

Inhibiting blood to save the brain

... coats nerve fibers. Past studies showed that the destruction of the myelin sheath is associated with the accumulation of fibrinogen deposits in the brain of human MS patients. In this study, Akassoglou and colleagues showed that fibrinogen is not merely associated with the damage in MS, but an active participa...

Minuscule molecules pack a powerful punch

...ing the activity of other genes, often by inducing destruction of protein-coding messenger RNAs or by preventing their activity in the cell. The research team, led by the Wellcome Trust Sanger Institute, targeted a gene called Bic/microRNA-155 (or miR-155) in embryonic stem cells which they used to transfer t...

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