Researchers discover a new genetic cause of Alzheimer's disease
...e suffer from this disease. The disease gradually destroys brain cells in the deep areas of the brain that are responsible for memory and knowledge. Ever since the disease was first reported by Alois Alzheimer − 100 years ago now − scientists have been searching diligently for ways to treat it. ...Researchers reverse juvenile diabetes in animal model
...sease because a person's immune system attacks and destroys the beta cells in the pancreas that produce insulin. Symptoms of type 1 diabetes usually develop over a short period of time and include increased thirst, frequent urination, constant hunger, weight loss, blurred vision and extreme fatigue. People wi...HIV accessory protein disables host immunity via receptor-protein intermediary
...covered that an HIV-1 accessory protein called Vpr destroys the host cell's ability to survive by binding to a host receptor. This, in turn, keeps an important enzyme from activating the cell's immune system. These findings refine an earlier understanding of Vpr HIV pathogenesis and imply new approaches to tr...Twin molecular scissors link creation of microRNAs with gene-silencing
...es of its target messenger RNA to cut. The cutting destroys the messenger RNA, effectively silencing the gene from which it was transcribed. "The two enzymes in the complex are like two scissors working together in a concerted fashion, connected and coordinated by the third member of the complex," Shiekhatta...New vaccine platform may fight infections with causes from influenza to bioterrorism
...cking the same population of immune cells that HIV destroys in humans. The vaccine platform developed by Children's Hospital of Pittsburgh researchers, working in collaboration with researchers from the University of Pittsburgh and Louisiana State University, suggests that the immune system can be primed to w...Scientists develop nanotech-laser treatment that kills cancer cells without harming healthy tissue
...University have developed a new laser therapy that destroys cancer cells but leaves healthy ones unharmed. The...and co-author of the study. "Standard chemotherapy destroys cancer cells and normal cells alike. That's why patients often lose their hair and suffer numerous o...Research casts doubt on circulating stem cells
...ases like Duchenne muscular dystrophy (DMD), which destroys all the body's muscles, appeared to be potentially treatable ?indeed, by the simple means of transplanting healthy bone marrow. For boys, DMD is the second most common hereditary disease. Due to a genetic defect, the muscles fail to produce properly ...UT Southwestern researchers discover master switch in cell death
...red enzyme, which the researchers have named Mule, destroys a key molecule at the top of the pyramid, thus leading to the cascading disintegration of the cell. Their findings also suggest a new drug target for controlling tumor formation. Dr. Xiaodong Wang, professor of biochemistry at UT Southwestern and a ...New imaging technology shown to detect pancreatic inflammation in type 1 diabetes
...leaky. Over time, this infiltration of lymphocytes destroys the beta cells, leading to high blood glucose and full-blown diabetes. Today, the only accurate method for detecting the progression or regression of insulitis is a biopsy of the pancreas, which is almost never performed because it is an invasive and...Secrets to antibody's success against West Nile Virus surprise scientists
..., scientists suspect that the host cell eventually destroys the virion. Fremont and colleagues, who publish their results in the Sept. 29 issue of Nature, hope to design a new diagnostic system that can determine whether vaccines for West Nile and related viruses undergoing clinical trials stimulate produc...Study: Harmless virus kills some cancers
... recognizes that the cancer cells are abnormal and destroys them. This suggests that AAV2 has great potential ...d to determine if the mechanism through which AAV2 destroys cancer cells is the same." Scientists often refer to cancer cells as deregulated, meaning they are ...New tool reveals secrets of migrating cells
...ing infections - or a killer T cell that seeks and destroys cells infected with virus. On the other hand, uncommitted or immature T cells, what they call meanderers, wander slowly and apparently randomly around the outer layer, or cortex, of the thymus, perhaps in search of that life-altering signal. Robey ...Green catalyst destroys pesticides and munitions toxins, finds Carnegie Mellon University
...developed at Carnegie Mellon University completely destroys dangerous nitrophenols in laboratory tests, according to Arani Chanda, a doctoral student who is presenting his findings on Sunday, Aug. 28, at the 230th meeting of the American Chemical Society (ACS) in Washington, D.C. (Division of Industrial and E...Stem cell treatment improves mobility after spinal cord injury
...dentified how the body's immune system attacks and destroys myelin during spinal cord injury or disease states. They also have shown that when treated with antibodies to block immune system response, myelin is capable of regenerating, which ultimately restores sensory and motor activity. Oswald Steward, Gabr...UCLA cancer researchers shake loose hidden biomarker
...d a commonly used cancer chemotherapy agent, which destroys the microtubules. "These patients are getting chemotherapy anyway, and once we move the PSMA to a more accessible area on the prostate cancer cell, we might be able to use antibody-based immunotherapies as well, and they could be administered in the...Fox Chase study shows that weakened T-cell receptor signals change T-cell lineage
... body mechanism that detects potential cancers and destroys them before their presence is evident to us, may be one function of the delta-gamma lineage, since gamma-delta T cells appear to be particularly adept at combating skin cancers," Wiest added. ...Turning viruses into allies against cancer
..., reported that the engineered virus seeks out and destroys liver cancer cells, leaving surrounding healthy tissue in tact. The iodine "transport" protein attached to the virus acts as a kind of homing beacon for radioactive iodine, providing a second line of attack against the cancer cells, technically know......ed how the right combination might form a web that destroys the cancer cell's communication network, ultimately demobilizing the cell. Three decades of intensive cancer research led to the identification of a family of receptors, known as HER, that sit antenna-like on the outside of the cell wall and are imp...Scientists discover how plants disarm the toxic effects of excessive sunlight
...hich is a highly reactive and toxic substance that destroys biological molecules. "We've discovered a pathway that cells use to turn on certain genes and respond to singlet oxygen," says Timothy Donohue, a professor of bacteriology in the university's College of Agricultural and Life Sciences and lead resear...