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Tag: "destroys" at biology news

Einstein researchers demonstrate a novel approach to treating AIDS

...ific protein target…and the radioisotope "warhead" destroys the cell to which that protein is attached. Radioimmunotherapy is an accepted treatment for several types of cancer including non-Hodgkins lymphoma. But only at Einstein has it been tried against infectious diseases­an idea pioneered by Dr. Ekater...

Genome info from 'plant destroyers' could save trees, beans and chocolate

...y and watermelon, to name a few. The pathogen also destroys an estimated 450,000 tons of cocoa beans with a resulting $400 million loss in chocolate production each year. The researchers found the pathogens have nearly twice as many genes as other fungal pathogens, and that more than 40 percent of the genes ...

Environmental toxins may cause body's defenses to worsen lung disease

...nks it's eradicating disease from the body when it destroys cells that have been damaged by environmental toxins, but in chronic lung disease that destruction may be doing more harm than good," he says. Chronic pulmonary diseases cause irreversible damage and inflammation in the lungs that lead to scarring ...

'Trojan Horse' agent halts bone metastasis in mice

...ceptors and, once inside, the "Trojan Horse" toxin destroys the cell, disrupting the ability of tumors to form blood vessels to supply the nutrients they need to grow. Animal studies previously conducted by the researchers have shown that the protein can selectively destroy blood vessels feeding human solid t...

HIV exploits competition among T-cells

...system recognizes the threat, mounts a defense and destroys most of the invading viruses. The second phase is a long period of clinical latency that can last up to 10 years. In this phase, a small amount of virus mutates fast enough to escape initial detection and continues to mutate over time. The third phas...

Killing brain tumors from within: A 'Trojan horse' approach

...normal cells. Once embedded in the tumor cells, it destroys them from within ?a true "Trojan horse," said Prof. Levitzki. Normal cells, which possess 20 to100 less receptors for EGF, are spared, since the amount of double-stranded RNA gobbled up is insufficient to induce them to die. The lethal RNA appr...

Solved: The mystery of flesh-eating bacteria's relentless attack

...regulates the production of ScpC, and ScpC is what destroys the interleukin-8," said Hanski. "In our strain, M14, SilCR is missing completely, which explains why it is so virulent." He said the work points to more effective strategies for treating Streptococcus infection. "There are different avenues you co...

'Molecular assassin' targets disease gene

... that finds its target, c-Jun, within the cell and destroys it," he said. "It is a specific, pre-programmed 'molecular assassin'." The paper in Nature Biotechnology shows the potential of c-Jun as a drug target in inflammation. It details tests in a variety of pre-clinical models showing how effective Dz13 i...

Study identifies substances in grapefruit juice that interact dangerously with some drugs

...med because an intestinal enzyme, CYP3A, partially destroys them as they are absorbed. Grapefruit juice, but not other commonly consumed fruit juices, inhibits this enzyme, allowing more of these drugs to enter the body. It was originally assumed that the ingredients responsible for drug interactions were t...

AIDS vaccine research offers new insights on survival

... the cells that have been infected by HIV and then destroys them so that the virus cannot continue replicating. "While this vaccine approach cannot actually prevent an infection, it can tamp down the AIDS virus, resulting in the development of a much milder form of the disease in vaccinated monkeys that subs...

Science captures the essence of fruit

...gular diet," he says. "Adding synthetic flavours destroys the credibility of any health food, so natural flavours produced through bioproduction would be a huge advantage to the health industry." ...

UCI scientists find chlorine may contribute to ozone formation

...ted. It must be rapidly produced, because sunlight destroys it so quickly," Saltzman said. "Most likely the process involves airborne marine particles, but research is needed to understand how it occurs." Inland ozone levels typically are higher than on the coast, mainly because of meteorological conditions ...

How can identical twins be genetically different?

... a protein called laeverin. This is an enzyme that destroys certain types of proteins. Scientists hypothesize that laeverin promotes the tissue damage of the joint found in RA by degrading cartilage and bone. Another previously unidentified gene codes for a protein called 11â-HSD2 that helps deactivate the ...

Tramiprosate (Alzhemed? preclinical results published in Neurobiology of Aging

...f daily living, alters the behaviour and gradually destroys the brain. AD is the most common cause of dementia in our aging population. Almost 5 million individuals in the United States alone currently suffer from the condition. The U.S. Alzheimer's Association estimates that by 2025, over 22 million people ...

With cochlear implants, earlier use leads to better speech

...t that a cochlear implant is forever -- the device destroys any residual hearing so that hearing aids are no longer an option. "Studies like ours are meant to help answer parents' questions about cochlear implants," Nicholas says. "Our overall goal is to focus on the best age for implantation. If the window...

The critical importance of mangroves to ocean life

... the ocean, however, the intense tropical sunlight destroys some of the most delicate dissolved organic carbon molecules. But more than half of the dissolved organic matter survives the attack from sunlight or bacteria. The authors measured the chemical signature in water samples from the massive mangrove f...

Anti-inflammatory drug's potentially deadly side effect found to be rare

... virus for the first patient it was identified in) destroys the cells that make protective sheaths surrounding brain cells. Symptoms include vision loss, mental deterioration, speech disturbances, loss of coordination and, in advanced phases, paralysis and coma. "It leaves the brain short-circuited," Cliffor...

Gene thwarts some pathogens, gives access to others, could save crops

...urrently, the gray mold disease caused by Botrytis destroys about 10 percent of the grape crop annually and about 25 percent to 30 percent of tomato and strawberry crops in some seasons. It also infects many other fruits, vegetables, bulbs and a variety of flowers, including petunias, geraniums and chrysanthe...

Genomics-based vaccine could prevent deadly cattle disease

Every year, East Coast fever destroys the small farmer's dream of escaping poverty in Africa. Killing more than a million cattle and costing some $200 million annually, this tick-borne disease rages across a dozen countries in eastern and central Africa. Now, an international team of sci...

Tool developed to silence genes in specific tissues using RNAi

... different, and sets in motion cell machinery that destroys the invading RNA. This involves cutting up the double-stranded RNA, separating it into single strands, and destroying other single-stranded RNA molecules that are complementary to those small RNA segments. Scientists quickly realized that if they co...

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