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Tag: "destroy" at biology news

Mouse study reveals new clues about virulence of 1918 influenza virus

...on days 1, 3 and 5 post-infection and processed to destroy any virus. The mouse genetic material (RNA) was then extracted from these lung samples and sent to the University of Washington team for analysis. Drs. Katze and Kash and colleagues examined the mouse RNA using microarrays to determine which genes...

Potato blight pathogenicity explained by genome plasticity

...rface allows other fungi and bacteria to enter and destroy the core, often resulting in a foul odor. P. infestans is related to approximately 65 other pathogens that cause similar damage to commercial crops as well as natural vegetation. In the potato- Phytophthora system, the host-pathogen response has...

A sweet solution for Alzheimer's disease?

...tes for Alzheimer's disease. A vaccine designed to destroy amyloid â, for example, was first tested successfully in the same type of mice used in the scyllo-inositol studies, but the vaccine turned out to be toxic in some humans. It caused an autoimmune reaction in about 10 percent of patients who were immun...

Bacteria give up secrets in war waged on plants

...tter understanding of how bacteria set up camp and destroy the plant's ability to fight infection in the July 14 issue of Science Magazine. He is an MSU professor of plant biology, plant pathology, and microbiology and molecular genetics. The secret weapon: a bacterium's protein targets a plant protein tha...

Finding paves way for better treatment of autoimmune disease

...ys. He theorizes that this natural substance helps destroy non-regulatory T cells when the body gets too many, say after fighting a big infection, and that it may not work well enough in people with autoimmune disease. ...

Combined treatment extends life expectancy for lung cancer patients

... microwave ablation, processes that heat tumors to destroy them. For patients who cannot have surgery or radiation, the median survival is about one year. In this study, researchers looked retrospectively at 41 patients treated over seven years with thermal ablation (RFA or microwave ablation) and either s...

Wild vs. lab rodent comparison supports hygiene hypothesis

... producing antibodies that bind to the invader and destroy it. Of the many classes of immunoglobulins (Ig), the IgG type is often involved in autoimmune disease, while the IgE type is likely a key defender against parasites and has been implicated in allergic reactions in humans, Parker said. For their exp...

Discovery of agile molecular motors could aid in treating motor neuron diseases

...a group of progressive neurological disorders that destroy motor neurons, the cells that control voluntary muscles for such activities as speaking, walking, breathing, and swallowing. When these neurons die, the muscle itself atrophies. A well-known motor neuron disease is amyotrophic lateral sclerosis (ALS,...

Study details hepatitis C ability to block immune system response

...type1 interferon by using its protease activity to destroy MAVS. By preventing infected cells from producing interferon, the virus inhibits the body's immune response against HCV, enabling it to persist. "Our new work shows that HCV does not induce interferon-? or antiviral interferon stimulated genes in ...

Study reveals how cells destroy faulty proteins in cystic fibrosis

...ells to work normally because their bodies quickly destroy the mutant protein. "Most cases of CF are caus... as ubiquitin. The ubiquitin tag tells the cell to destroy the marked CFTR, a process overseen by a destroyer called the proteasome. This trash system is known...

Experimental RNA-based drug kills prostate cancer cells effectively and safely

...state cancer cells and then springs into action to destroy them, while leaving normal cells unarmed. The drug, developed at Duke University Medical Center, uses one type of genetic material, called targeting RNA, to enter cancer cells, and another type, called silencing RNA, to stop the expression of a pro...

T cells activated to fight HIV basis for dendritic cell therapeutic vaccine

...iller T cells to more efficiently find, detect and destroy HIV infected cells. Our vaccine, as an immunotherapy, is custom-designed to target the unique virus that has evolved in each individual being treated. A patient's own dendritic cells together with their unique viral antigens comprise the main element...

'Sticky' mice lead to discovery of new cause of neurodegenerative disease

...ells were making an unsuccessful effort to tag and destroy the accumulating misfolded proteins. "Our finding that this mechanism underlies a neurodegenerative disease was highly unexpected," said Ackerman. "It was perfectly obvious that mischarged tRNAs, may generate misfolded proteins. But what surprised...

Research reveals inner workings of immune system 'thermostat'

...lso trigger inflammation, which, if unchecked, can destroy tissue, induce shock and kill the host. So immune ... make enough of the pro-inflammatory warriors that destroy harmful bugs and cause inflammation. This finding established the notion that tyk2 signaling control...

Friendly bacteria in chewing gum that bites back

A chewing gum containing good bacteria that can destroy the bad bacteria that cause tooth decay could be in the shops soon reports Marina Murphy in C&I. The gum is one of several products being developed by German chemical company BASF using the bacteria Lactobacillus, which is normally found in live ...

Buckyballs boost antibody's chemotherapy payload

...too many covalent bonds, the chemical changes will destroy its ability to recognize the cancer it was intended to attack. Wilson said the team from Rice and M. D. Anderson had planned to overcome this limitation by attaching multiple molecules of Taxol to each buckyball, which would then be covalently conne...

UC Davis researchers move biotechnology closer to replacing electronic pacemakers

...invasive technique cardiologists use in clinics to destroy the heart cells that cause abnormal electrical discharges and rapid heart rates in their patients. To restore the SA node function and evaluate the bioengineered cells, Li's team then implanted electronic cardiac pacemakers like those used in humans ...

First human study confirms that immune cells can be a primary cause of bone loss in gum disease

...actor in the regulation of osteoclasts (cells that destroy bone). Dr. Kawai's research examined the receptor activator of NF-kB ligand, (RANKL)-mediated osteoclastogeneis, and the pivotal role it plays in inflammatory bone resorption. The aim of this study, which will be published in the September issue of ...

Synthetic molecule causes cancer cells to self-destruct

...en pathway, we can use the cells' own machinery to destroy themselves." To find the compound, called procaspase activating compound one (PAC-1), Hergenrother, with colleagues at the U. of I., Seoul National University, and the National Center for Toxicological Research, screened more than 20,000 structurall...

Mice lacking key immune component still control chronic viral infections

...m must have MHC Class I molecules to recognize and destroy virus-infected cells," says senior author Skip Vir... cells recognize a viral protein part, they either destroy the cell displaying the part or emit inflammatory hormones known as cytokines that trigger other imm...

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