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Tag: "destroy" at biology news

Antibody signal may redirect inflammation to fuel cancer

...-like white blood cells, or leukocytes, engulf and destroy invading microbes when receptors on their surface receive a signal from serum in the blood -- often an antibody produced by a B cell in the separately evolved "acquired" immune system. Now UCSF researchers have found that in the presence of preca...

Batten down the hatches against HIV

...portant for a good immune defense; they detect and destroy virus-affected cells. However, they themselves are among the targets attacked by HIV. In order to enter into a T-cell, the virus must first dock to a receptor known as CD4. Also involved is the co-receptor CXCR4. The use of short interfering RNA stra...

Targeting tumors the natural way

...e used can direct an endogenous immune response to destroy cancer cells selectively," says Kiessling. "We think this could lead to a new class of therapeutic agents not only for cancer but also for other diseases involving harmful cells." Cancer cells typically display higher levels of certain receptors on...

Reactivated gene shrinks tumors

...DNA damage is irreparable, p53 induces the cell to destroy itself by undergoing apoptosis, or programmed cell death. When p53 is turned off by mutation or deletion, cells are much more likely to become cancerous, because they will divide uncontrollably even when DNA is damaged. In this study, the resea...

How T lymphocytes attack

...sts reveals the strategy adopted by these cells to destroy the tumour. Recognition of the tumour antigen determines T lymphocyte behaviour To arrive at their conclusion, the researchers used an animal model to observe the route followed by T lymphocytes in tumours endowed with a particular antigen, o...

Many couples choose to donate surplus embryos for stem cell research

..., most importantly, almost no couple wants just to destroy the embryos," Menendez said....

Creating new life forms that may help eradicate cancer affecting women

...hese cells do is enlist killer T cells to seek and destroy tumor cells that over-express the HER-2/Neu molecule. This is significant because HER-2/Neu is over- expressed in 20%- 40% of all breast cancers. As Dr. Shababi explains: "We not only created a new breast cancer vaccine, but also have a new lif...

Nanoparticles for delivery of prostate cancer treatment

...wei Hu have developed a way to directly target and destroy the blood vessels of solid tumors, thus destroying...like molecule that activates an immune response to destroy the tumor blood vessels and associated tumors. Garen previously received grants from the Nationa...

Common cold virus may kill breast cancer cells

...heory, the virus is able to selectively target and destroy many different types of cancer cells, including breast cancers, whilst leaving normal cells unaffected," she said. Debilitating symptoms associated with conventional treatments (such as nausea, vomiting and hair loss) could also be avoided by using...

Decoy pill saves brain cells

...r glutamate, which tells neurons to fire, can also destroy them. If over-activated, glutamate receptors start a chain reaction that raises the concentration of calcium and activates calpain, among other toxic enzymes. But Baudry and Xu observed that in one receptor, mGluR1?, the situation is even worse. U...

St. Jude announces breakthrough in eye cancer treatment

... possible therapies such as radiation or lasers to destroy the remaining cancer cells in the eye. "When successful, this therapy often saves vision," Wilson said. "Clinicians at major medical institutions generally save 70 percent of all eyes treated, even in the case of advanced disease." ...

Early-stage immune system control of HIV may depend on inherited factors

...olecules display to the T lymphocytes that usually destroy infected cells. In a report in the November issue...ivate the CD8 cytotoxic T lymphocytes that usually destroy infected cells. Although the CD8 response against HIV is ultimately ineffective in protecting infec...

OHSU researchers demonstrate how white blood cells cannibalize virus-infected cells

... in the body's immune system. The cells attack and destroy disease "invaders" such as viruses in the body. Pr...anes and outer surfaces of diseased cells. As they destroy and cannibalize the fluorescently labeled cells, they become labeled with the fluorescent dye themse...

Why don't all moles progress to melanoma?

.... If that doesn't work, the UPR causes the cell to destroy itself in a process called apoptosis. "Traditionally, the ER's role was considered to be limited to protein folding or protein modification," Soengas says. "But scientists like Randal Kaufman, a U-M professor of biological chemistry and co-author o...

Heart smart: new drug improves blood flow

...ry and allow more blood through. But free radicals destroy a key enzyme that allows the arterial cells to respond in this way, so the signal doesn't get through. However, the new drug ?developed by Bayer HealthCare ?reactivates the damaged enzyme. "Our results show that the drug directly binds to and rep...

Transplanted brain cells hold promise for Parkinson's disease

...s were done shortly after a neurotoxin was used to destroy neurons that make dopamine, a neurotransmitter key to movement control, Dr. Borlongan notes. This would be equivalent to a patient getting treatment very early in the disease process, which rarely happens since there is no screening test to catch it ...

Scientists discover way to block growth of prostate cancer cells

...ther than decreasing, oxidative stress in order to destroy established tumours. However, no one that I know has tried to reduce oxidative stress by blocking polyamine oxidation to prevent prostate tumours, and this is what we set out to do." Having discovered the role played by polyamine oxidation, the ...

Clue found to Epstein-Barr virus' ability to form and sustain tumors

...hat opens the door for the development of drugs to destroy tumors caused by Epstein-Barr virus (EBV). The finding, published in the Sept. 4 Proceedings of the National Academy of Sciences Online, identifies the activity of a critical segment of a viral protein required to sustain EBV-related tumors. The re...

Environmental toxins may cause body's defenses to worsen lung disease

...ing agent), the immune system immediately wants to destroy the damaged cells so healthy tissue can take over,... epithelial cells lining the lungs to identify and destroy diseased cells. If the lymphocyte recognizes the tissue, Borchers explains, it simply continues its ...

Ebola-outbreak kills 5000 gorillas

...points out that Ebola has the potential to quickly destroy years of ecotourism investment. For example, Bermejo’s gorilla habituation program at Lossi was set up in the mid-1990’s in collaboration with the European Union’s Ecosystem Forestiere d’Afrique Centrale (ECOFAC) project to bring ecotourism revenue t...

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