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Tag: "designing" at biology news

Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer

...ty of Torino in Italy, discuss the difficulties in designing studies of DNA repair capacity and the need for the development of better laboratory tests for such studies. "When DNA repair capacity can be measured easily and quickly, the scientific community will be able to clearly understand the role of DNA rep...

UAB scientists discover the origin of a mysterious physical force

...search, since a substantial part of the process of designing new drugs is based on understanding how substances penetrate cell membranes to enter cells. These drugs are often proteins designed to prevent or strengthen the action of other substances. In these cases, accurately identifying the protein folding is...

Protein discovery could unlock the secret to better TB treatment

...lar structure of this protein will lead the way to designing drugs which enable treatment of dormant and multidrug resistant TB. In England and Wales around 400 people die each year from the disease. The top challenge for TB control in the European region is multidrug-resistant TB (MDR-TB). Eight per cent of ...

New binding target for oncogenic viral protein

...ys that cause cancer. This is an important step to designing new cancer treatment strategies that target these pathways," concluded Dr. Clurman. ...

Research advances quest for HIV-1 vaccine

...ns from many potentially harmful viruses. However, designing a suitable vaccine for HIV-1 has been a highly challenging and thus far unsuccessful endeavor. HIV-1 is enormously variable and it has been difficult to isolate antibodies that will recognize the many different strains of the virus. The antibody 4E10...

Scientists seek answers on what activates deadly anthrax spores

...ick out structural vulnerabilities that are key to designing new therapeutic agents to prevent anthrax. Interest in determining how to stop anthrax remains high, not only after the 2001 attacks through the mail that resulted in 18 cases and five deaths, but also after the recent scare at two military mailroom...

Female sex hormones play a vital role in defense against sexually transmitted diseases

...y could start. Additionally she says, if they were designing a vaccine trial against HSV-2 and if the mice results hold true for women, they could suggest vaccination protocols under combination hormone therapy to get the best benefit from the vaccine. Work in this area is important because one in every four ...

UCSD discovery may help extend life of natural pesticide

...esticides that work through different receptors or designing pesticides that can work through more than one receptor type could thwart the development of resistance. "This paper presents an intriguing question," said Griffitts. "In light of findings by insect biologists that certain proteins function as impor...

Scientists identify new model Of NK cell development

... NK killer cells that may ultimately be helpful in designing more effective treatments for cancer and other diseases says Caligiuri. "NK cells are the 'minutemen' of the defense system ?the first to respond to an attack. The more we know about them, the more we can help them do their work. In cancer, as in ot...

RNA project to create language for scientists worldwide

...rmal and abnormal metabolism and physiology and in designing new strategies for intervention in the form of gene therapy, Leontis said. ...

Asthma gene clusters identified

...The discovery opens the door to the possibility of designing treatments specifically tailored to children who suffer from the severest forms of asthma. The findings appear in the Feb. 10 issue of the Journal of Allergy and Clinical Immunology. The study is based on an Affymetrix "GeneChip" analysis of RNA is...

Flocking together: Study shows how animal groups find their way

...n understanding how humans behave in crowds and in designing robots that explore remote locations such as the o...gical insights, the research may provide ideas for designing robots that work together in groups, said Couzin, who has collaborated with roboticists at Princeton...

New component of the 'brakes' on nerve regeneration found

...yelin inhibition adds a new level of complexity to designing therapeutic strategies for treating CNS injury." T...lin inhibition may provide important insights into designing therapeutic strategies to block myelin inhibition and cell death in the context of CNS injury," they...

New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal

...utwitting the traditional antibiotic arsenal. Yet designing and testing new antibiotics can be a maddeningly slow and costly process ?if pharmaceutical companies even bother, says Hartmut Derendorf, chairman of the department of pharmaceutics at the University of Florida College of Pharmacy. Many would rather...

Medical molecules designed to respond to visible light that can penetrate tissue

...ch. Brewer will also give an oral presentation on designing photochemical molecular devices and applications in photodynamic therapy and in solar energy conversion. Because of the detail offered by Mongelli's poster, Brewer says she will focus on the exciting potential of creating molecules to reduce water to...

To control germs, scientists deploy tiny agents provocateurs

...nt and animal bacteria, Blackwell and her team are designing new compounds that mimic acylated homoserine lactones (AHLs), a natural molecule that is used by more than 50 species of bacteria to "talk." Researchers have so far studied around 15 variations of AHLs. In particular, the UW chemists are synthesizing...

Genetic defects give the immune system the green light to attack the pancreas

... diabetes,?said Dr. Yamagata. “We then can work on designing ways to subdue or stop this process.?/p> This study was supported by the Juvenile Diabetes Research Foundation (JDRF), in the context of the JDRF Center on Immunological Tolerance in Type-1 Diabetes at Harvard Medical School. ...

Brain-injury rehabilitation depends on acetylcholine circuitry

...ntations will likely be an important precursor for designing therapeutic strategies to enhance functional recovery following nervous system injury," the researchers wrote. "The present study makes a significant contribution toward this goal by identifying the basal forebrain cholinergic system as an essential ...

UCSD research reveals mechanism involved with type of fatal epilepsy

...of the disease. Dixon and colleagues are currently designing experiments to test these models with the hope of gaining the necessary insights to develop potential therapies for Lafora disease. Co-authors are Matthew S. Gentry, Ph.D., and Carolyn A. Worby, Ph.D., both of the UCSD Department of Pharmacy. This r...

Protein Discovery Could Unlock The Secret To Better TB Treatment

...lar structure of this protein will lead the way to designing drugs which enable treatment of dormant and multidrug resistant TB. In England and Wales around 400 people die each year from the disease. The top challenge for TB control in the European region is multidrug-resistant TB (MDR-TB). Eight per cent of ...

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