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Tag: "design" at biology news

Scientists design potent anthrax toxin inhibitor

...-scale animal tests. "This novel approach to the design of anthrax antitoxin is an important advance, not ..., but also because this technique could be used to design better therapies for cholera and other diseases," says NIH Director Elias A. Zerhouni, M.D. The res...

Warbling whales speak a language all their own

...f those elements. Suzuki wanted to see if he could design a computer program that enabled scientists to classify the structure of the whales' songs. He used the program to analyze structural characteristics of the humpback songs recorded in Hawaii. To measure a song's complexity, Suzuki analyzed the aver...

Mayo Clinic collaboration discovers protein amplifies DNA injury signals

...ortant start to understanding how we might one day design new treatments that help this repair system recover from injury or resist injury." Dysfunction of the DNA damage response pathway makes the gene unstable. Genomic instability is the driving force in tumor formation, which is why cancer researchers a...

New University of Toronto research a 'pore' excuse for engineering

... chemistry can provide innovative solutions to the design of novel materials." ...

UW-Madison engineers squeeze secrets from proteins

...do not unfold when you put them in hot water. They design enzymes that are more stable than normal enzymes at high temperatures." To better understand protein folding, de Pablo's team built computer models of proteins under different types of confinement. These models were then simulated to gain a better u...

Novel molecular 'signature' marks DNA of embryonic stem cells

...ng the cells' unique plasticity." The remarkable design of bivalent domains, which has not been previously described, merges two opposing influences ?one that activates genes and another that represses them. When combined in this way, the negative influence seems to prevail and, as a result, the genes pos...

UCSB researchers discover shape matters to macrophages

... discovery, for example could allow researchers to design drug carriers that can be purposefully retained by the body for a longer period of time, or could help researchers create vaccines that would be quickly removed to stimulate a rapid immune response. ...

Lactic acid not athlete's poison, but an energy source - if you know how to use it

...gen. "Our findings can help athletes and trainers design training regimens and also avoid overtraining, which can kill muscle cells," Brooks said. "Athletes may instinctively train in a way that builds up mitochondria, but if you never know the mechanism, you never know whether what you do is the right thi...

NJIT engineer poised to take stem cell research a step forward

...in cartilage repair and arthroscopic surgery, will design and interpret the animal models used to test the stem cell repair of cartilage. Rizio will also teach Arinzeh, and some of her students, how to insert stem cells in to patients' knees during surgery. Arinzeh's drive to advance the science of stem c...

New cellular flaw found in some virulent breast cancers

...dults. However, said Sicinski, it is difficult to design a drug to neutralize the action of a protein like ...cinski, adding that while it would be difficult to design a drug to inhibit the action of a protein like cyclin D1, blocking a kinase is significantly easier....

Study in Science holds promise for a new approach to drug therapy

...e on the outside of a cell membrane, we could also design drugs that interfere with the same pathway later in the process, when the disease-causing signal has passed from ligand to GPCR to the G protein subunit to enzymes within the cell? Study Methods Medical center researchers have been studying G p...

How 'hot' emotional brain interferes with 'cool' processing

...nce by emotional distraction," said Dolcos. "The design of these experiments gave us an excellent chance t...stem and impaired performance. "The experimental design mimicked the kind of distraction people experience in everyday life," Dolcos added. "For example som...

Protein 'nanosprings' most resilient found in nature

..."Ankyrins appear to have a very unusual structural design ?consisting of short anti-parallel alpha helices that self-assemble into stacks -- that allows them to quickly and robustly unfold and refold," Bennett said. "It's hard to believe, but it happens. You have to wonder whether their structure plays an i...

Watching the brain switch off 'self'

...mental challenge that the researchers faced was to design one task that could be used to activate specifically either sensory processing or introspection brain areas. Their solution was to ask subjects to look at the same pictures or listen to the same musical phrases, but to perform two different kinds of ...

USC, Rice to develop bacteria-powered fuel cells

...tter experiments, and the laboratory tests help us design better simulation, and the overall combination saves time and money." In addition to the computational modeling, Lüttge will contribute his experimental skills in an imaging technique called Vertical Scanning Interferometry. The technique, which he ...

Protein finding could lead to treatment for inflammatory diseases

... important one," Shisler said. "Another goal is to design a drug that would override the activity of the protein as a cure for MCV." ...

Georgia Tech accelerates drug discovery with new IBM supercomputing cluster

...lSouth worked closely with Georgia Tech and IBM to design a unique, reliable hosting environment to support the high power density supercomputing cluster. "With our hosting background, we had the flexibility and experience to quickly create a one-of-a-kind solution that could support Georgia Tech, IBM and ...

St. Jude projects 90 percent cure rate for ALL

... the risk of relapse in a specific patient, we can design the most effective treatments possible at the start of therapy. That's a key element of our success in raising the cure rate for ALL while limiting toxic effects of therapy." That success is based to a large extent on the work done at St. Jude and e...

Losing sleep undoes the rejuvenating effects new learning has on the brain

...archers concluded. "This finding could be used to design training regimens for chronically sleep-deprived people, including members of the military and medical students," Hairston said. "That said, while the cognitive impairment may be overcome, our findings indicate that mild, chronic sleep restriction ma...

Molecular mechanism may explain how fevers spark seizures

...hat we know a vulnerable step, we can in principle design therapeutic strategies to overcome it." ...

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