design 2 10

Tag: "design" at biology news

Johns Hopkins lab scientists tame overactive CF protein

... "The hope is that these findings will be used to design therapies and drugs that go beyond symptom management and actually restore normal cell function to prevent CF," says senior investigator Pamela Zeitlin, M.D., a pulmonologist at the Children's Center, although she warned that they are years from deve...

Ultrasound may help regrow teeth

...tional Institute for Nanotechnology. The wireless design of the ultrasound transducer means the miniscule d...earing about Chen's expertise in nanoscale circuit design and nano-biotechnology, El-Bialy explained his own research and asked if Chen might be able to help ...

Mice lacking key immune component still control chronic viral infections

... that backup may become a new focus for efforts to design antiviral vaccines. "This surprising finding contradicts a long-held belief about control of viral infection: that the immune system must have MHC Class I molecules to recognize and destroy virus-infected cells," says senior author Skip Virgin, M.D...

Chimpanzees can transmit cultural behavior to multiple 'generations'

...e National Academy of Sciences. Using a research design that simulated transmission over multiple generations, researchers Victoria Horner, PhD, of the University of St. Andrews and the Yerkes Research Center, along with Yerkes researcher Frans B.M. de Waal, PhD, and St. Andrews researcher Andrew Whiten, ...

How can identical twins be genetically different?

... into the nature of the disease and facilitate the design of novel treatment strategies for RA," says Holoshitz. ...

Viral genetic differences are possible key to HIV dementia

...ly." Or, he speculates, "we might actually try to design a drug to target these genetic variants that are responsible for the neurological damage." Pillai notes that the issue of HIV dementia is particularly important in regions outside North America and Europe where state-of-the-art antiretroviral medic...

Hopkins researchers develop new tool to watch real-time chemical activity in cells

...ell chemicals do their work. Scientists could then design new drugs to go to specific places within cells to work more efficiently. Also, streamlining the one-at-a-time approach offers the chance to study - and rule out or in - many potentially useful chemicals at once. What Zhang's team developed is a b...

MIT 'seeing machine' offers hope to blind

...S.B. 2003) and Shima Rayej (S.B. 2004), who helped design and construct the seeing machine. "We essentially made the new machine from scratch," Goldring said. While still allowing the projection of images, video and more onto a person's retina, the new desktop device costs much less than its predecessor in...

Rice scientists unveil 'nanoegg'

...ers gain greater and greater sophistication in the design and manipulation of light-active nanostructures," said LANP Director Naomi Halas, the Stanley C. Moore Professor of Electrical and Computer Engineering and professor of chemistry. "The addition of nanoeggs and, earlier this year, nanorice to LANP's f...

Connect the Quantum Dots

...y of Sciences has significant implications for the design of disease markers and the development of chemoreceptors used in human biomedical research. The groundbreaking study, entitled, "A Mechanism to Signal Receptor-Substrate Interactions with Luminescent Quantum Dots", demonstrates that quantum dots can ...

Researchers identify human DNA on the fast track

...essed in cells that have a fundamental role in the design and development of the mammalian cortex." And beyond HAR1 lie HAR2, HAR3, and so on through the 49 regions Pollard identified with her DNA screen. "We've only studied one of these regions carefully," said Haussler. "Now we have to go through the ot...

Viral hitchhiker inhibits Wolbachia bacteria's ability to proliferate

...mans or harm agriculture. It might also enable the design of alternative therapies for debilitating illnesses such as river blindness and elephantiasis, whose pathologies are caused by Wolbachia bacteria living in the parasitic worms associated with these diseases. The new research, led by Seth Borden...

Combating anthrax: Results of study published this month as researchers look for a better vaccine

...udies," he said. "We'll be using this data to help design strategies for testing of this vaccine in the future." Gorse indicated that the investigational vaccine, made by VaxGen Inc., demonstrated a clear relationship between the amount of vaccine administered and the subsequent immune response. The study...

Schepens scientists are first to discover angiogenesis switch inside blood vessel cells

... stable vessels," he says. "Our discovery may help design drugs that could dismantle existing vessels by targeting this switch inside the vessel cells." Angiogenesis is an important natural process that can be both good and bad for the body. It restores blood flow after injury, prepares a woman's body for...

Study reveals how cells destroy faulty proteins in cystic fibrosis

...h the protein -- information that will help people design better therapeutics for the disease," Cyr said. ...

Mussels evolve quickly to defend against invasive crabs

...if they recognize Hemigrapsus. And, crucial to the design of Freeman's study, Hemigrapsus is not present north of mid-coast Maine. "This set up a chance to look at populations that had been exposed to the predators for varying lengths of time," says Freeman. "We wanted to know, how is it that these mollus...

Unique dual target specificity of kinase inhibitor key for success against cancer

...ily represents a rational and promising target for design of new cancer therapeutics. Dr. William A. Weiss, from the Department of Neurology at the University of California, San Francisco and coworkers sought to identify which PI3 kinase isoforms are critical for growth and progression of malignant glioma c...

Mapping the protein world

... pathogenic bacteria or viruses will contribute to design new revolutionary therapeutic strategies." To meet this objective the scientists intend to study crystals of proteins bound to diverse drug candidates or containing different types of large molecules. "ARP/wARP needs to meet a two fold challenge:...

UCSD researchers develop 'smart petri dish'

...tachi Chemical Research Center in Irvine, Ca. The design of the new device builds on a previous development...arger particles such as bacteria and viruses. This design effectively persuades the cells to behave collectively the way they do in a fully functioning liver....

NYU researchers decorate virus particles, showing potential to enhance MRI capabilities

...RI capabilities. "If a radiologist wants to design a versatile probe that can be used in a variety of different imaging protocols, a chemically modified virus particle now appears to be an attractive option for this type of sophisticated application," he noted. "For example, if we can decorate the pa...

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