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Tag: "derived" at biology news

Fox Chase Cancer Center scientists identify immune-system mutation

...also for helping other white blood cells (B cells, derived from bone marrow) generate antibodies against foreign agents that enter the body. Other T cells are known as killer cells because they attack foreign invaders more directly. "The maturation of T cells involves key branch points at which cells choose...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...corporated bythe stem cells when they are grown or derived from laboratory culturesthat contain animal source...um replacements, apparently because these are also derived fromanimal products," said both papers' senior author Ajit Varki, M.D.,UCSD professor of medicine an...

Research advances quest for HIV-1 vaccine

...ferent strains of the virus. The antibody 4E10 was derived from HIV-1 infected patients by Dr. Hermann Katinger in Vienna and is the broadest acting neutralizing antibody against HIV-1 that is currently known. This antibody recognizes a protein called gp41 that is found on the surface of the virus. The gp41 ...

Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible

...ampa,Fla. All five cell lines and RNA samples were derived from lungcarcinomas, while the tissue samples were derived from multiple normaland cancerous tissues. The labs followed a common protocol for allsteps of sampl...

Spider Venom Could Yield Eco-Friendly Insecticides

...ill most likely lack resistance to bioinsecticides derived from funnel-web venom. Another strategy is to insert a gene for encoding a spider toxin into viruses that are specific to a particular insect genus, or even a small number of species within a genus. The toxin-enhanced virus would act like a magic in...

Scientists rid stem cell culture of key animal cells

...ells. Xu became interested in unveiling molecules derived from the mouse feeder cells because, in their absence, stem cells start to differentiate within two to three days. Xu started by evaluating the effect of changing stem cell growth conditions - using less feeder cell material, or no serum replacement,...

New Study from Affymetrix Laboratories Points to Changing View of How Genome Works

...ied RNAs that have this sequence. Most transcripts derived from the sparsely transcribed regions between centers of dense transcription are non-polyA transcripts. This study focused on an in depth scan of 10 chromosomes; however, Affymetrix has developed tiling microarrays that cover all human chromosomes. ...

Genetically modified natural killer immune cells attack, kill leukemia cells

...ll transplantation. In this case, NK cells will be derived from the transplant donor, expanded and genetically modified. These modified NK cells will then be infused into the patient after the transplant in order to eliminate residual leukemic cells. In another application, NK cells could be obtained from a ...

UCSD researchers maintain stem cells without contaminated animal feeder layers

...he Whittier Institute. Currently, stem cell lines derived from human embryos are grown and nourished in petr...ons is timely, given the recent report of 17 newly derived stem cell lines available for non-federal research. The findings here may facilitate the derivation ...

Scientists document complex genomic events leading to the birth of new genes

...terized by Dr. Bork and his colleagues was largely derived from RanPB2, but it had also acquired a domain from the neighboring GCC2 gene, whose protein product contains a GRIP domain that localizes intracellularly to the trans-Golgi network. The new gene family, spanning approximately 10% of human chromosome...

UCSD team discovers specialized, rare heart stem cells in newborns

...synthetic tissue grafts, and artificial and animal derived valves to surgically repair heart defects. While progenitor cells won't grow a whole new heart, our research has shown that they can spontaneously become cells from specific parts of the heart by simple co-exposure to other heart cells, which could a...

Genrate: a generative model that finds and scores new genes and exons in genomic microarray data

...nce data. GenRate balances probabilistic evidence derived from different sources and outputs scores (log-likelihoods) for each gene model, enabling the estimation of false-positive and false-negative rates. The model has a number of local minima that is exponential in the length of the DNA sequence data, so...

How the environment could be damaging men's reproductive health

...we think the fact that exposure to environmentally derived chemicals can change the sex chromosome ratio in sperm is worrying in itself and requires more attention from scientists and the public," said Prof Giwercman. The second study by researchers from Denmark, Lithuania and Finland[2] suggests that a hig...

Scientists discuss improved biopesticides for locust control in West Africa

...in January. Biopesticides are types of pesticides derived from natural materials such as microbes, principally viruses, bacteria, and fungi. "The biopesticide that is registered for use in West Africa derives from a fungus that is a specific pathogen of locusts and grasshoppers. It specifically targets thos...

DuPont's first biologically derived polymer receives global recognition

...ewest polymer innovation, the first DuPont polymer derived from a biological source, has been recognized by the China State Intellectual Property Office and China Central Television (CCTV) as "Most Visionary Innovation" at a recent award ceremony. Also, on Feb. 25, DuPontTM Sorona® will receive the 2005 "...

A human parasite with a streamlined mitochondrion

...ganelle, called a mitosome, that is evolutionarily derived from mitochondria. As reported by researchers this week, the mitosome can represent a surprisingly pared-down version of the much more sophisticated mitochondrion. In their new work on the mitosome, a team led by Edmund Kunji at the MRC Dunn Unit, J...

Single stem cells from bone heal a broken heart

...onstration of a single, human stem cell population derived from the bone marrow that has the capacity to induce generation of new heart cells and formation of new blood vessels ?two key components of successful myocardial repair. The results provide a foundation on which new approaches to repair the damaged ...

Promising new West Nile therapy cures disease in mice

...mice infected with West Nile virus. But antibodies derived from human blood have potential disadvantages: they vary in their ability to fight the disease, and although all precautions are taken to purify the antibodies, the blood might harbor other potentially dangerous infectious agents. The Washington Uni...

Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells

...ll transplantation. In this case, NK cells will be derived from the transplant donor, expanded and genetically modified. These modified NK cells will then be infused into the patient after the transplant in order to eliminate residual leukemic cells. In another application, NK cells could be obtained from a ...

Canada approves marijuana-based pain spray

...tivex, a novel prescription pharmaceutical product derived from components of the cannabis plant shown to have therapeutic properties. Sativex is administered via a spray into the mouth. Health Canada has approved Sativex with conditions, under the Notice of Compliance with Conditions (NOC/c) policy. This a...

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