Iron Deficiency Sparks Dramatic Changes In Gene Expression
...said.Until now, however, a cell's response to iron deprivation was poorlyunderstood. In the Duke study, Thiele an...nes isunknown, meaning that side effects from iron deprivation may gounattributed to their root cause. Other genes affected by ironstarvation are known to be vital...A frog's life is food for thought
...ittle is known about the effects of prolonged food deprivation on the gut of animals that go without food for long periods. Ms Cramp's study is helping explain why animals such as the green-striped burrowing frog are able to gorge themselves on huge meals without overwhelming their digestive system. "Nothing wa...Discovery Promises Simpler Therapy for Sickle Cell Disease
...the disease's primary symptoms -- including oxygen deprivation and blocked vessels that can lead to pain, clots and stroke. Thus, therapies that restore nitric oxide to blood cells might serve as a useful method for treating the disease, said HHMI researcher Jonathan Stamler, M.D., professor of pulmonary medicin...Buying Time Through Hibernation on Demand
...'s ability to use oxygen, Roth said. Using oxygen deprivation to depress metabolic activity also might extend th... said. Yet another potential application of oxygen deprivation would include accelerating wound healing in patients, such as diabetics, whose ability to do so is c...U-M team recovers ancient whale in Egyptian desert
...'s ability to use oxygen, Roth said. Using oxygen deprivation to depress metabolic activity also might extend th... said. Yet another potential application of oxygen deprivation would include accelerating wound healing in patients, such as diabetics, whose ability to do so is c...Unlike other mammals, newborn dolphins and orcas stay active 24/7 during first months of development
...to adult levels. In fact, past findings that sleep deprivation for two to three weeks can be lethal in rats and flies has led to the belief that sleep is critical for the development of brain and body and serves a vital function in adults. The ability to remain active and responsive after birth has several appa...Brain Scan Study of Smokers Reveals Signature of Craving
...e, how they respond depends on the degree to which deprivation leads them to crave cigarettes. "Smokers' respons... examined smokers only after a period of overnight deprivation from smoking. To further explore this phenomenon, the researchers examined smokers' brain responses...New study finds how cells with damaged DNA alert the immune system
...of abuse, including heat shock, pH changes, oxygen deprivation and starvation. However, the only type of stress that set off the sequence of events associated with impairment of a cell's genetic material -- the DNA damage pathway -- was exposure to radiation and chemotherapy drugs. They found that cells in whic...Renewed hope for Parkinson's patients
...of abuse, including heat shock, pH changes, oxygen deprivation and starvation. However, the only type of stress that set off the sequence of events associated with impairment of a cell's genetic material -- the DNA damage pathway -- was exposure to radiation and chemotherapy drugs. They found that cells in whic...Hunger in America rises by 43 percent over last five years
... 1999-2001. "With this astonishing level of food deprivation in America," Brown concluded, "we need President Bush to step up to the plate. If he now asks Congress to cut federal food programs, hunger will increase even further. We need the moral leadership to stem this crisis." ...Once-dreaded leprosy 'replaced' by tuberculosis, say researchers
...tuberculosis. This was exacerbated by the lives of deprivation that the lepers were forced to live as social outcasts. Ultimately, the scientists theorize, so many of the lepers died of tuberculosis until there were too few of them to further spread leprosy. TB, meanwhile, was increasingly on the rise as people...Molecular cabal contributes to stroke damage
...lecular effects. Their analyses revealed that such deprivation triggered NMDARs, which in turn activated an important cell switch called CaMKII. This enzyme, they found, acts on a particular ASIC, called ASIC1a, to greatly enhance its sensitivity to the acid induced by ischemia. This increased sensitivity causes...Clocking in Pillow Time without the Pillow
..., and heart problems. Indeed, the effects of sleep deprivation can be so serious that some sleep scientists liken...e sack, drugs that counteract the effects of sleep deprivation could serve as substitutes. In a new study, Sam Deadwyler and colleagues have explored this possibil...Noise And Delays Explain Why Some Genes Oscillate In Activity
..., and heart problems. Indeed, the effects of sleep deprivation can be so serious that some sleep scientists liken...e sack, drugs that counteract the effects of sleep deprivation could serve as substitutes. In a new study, Sam Deadwyler and colleagues have explored this possibil...Morning grogginess more debilitating than sleep deprivation, according to CU-Boulder study
...cognitive deficiencies following 24 hours of sleep deprivation have previously been shown to be comparable to the effects of alcohol intoxication, he said. The study appears in the Jan. 11 issue of the Journal of the American Medical Association. Study authors included Wright and Adam Wertz of CU-Boulder's int...Losing sleep undoes the rejuvenating effects new learning has on the brain
...heir obligations by getting less sleep. But sleep deprivation impairs spatial learning -- including remembering how to get to a new destination. And now scientists are beginning to understand how that happens: Learning spatial tasks increases the production of new cells in an area of the brain involved with spa...Sleep deprivation doubles risks of obesity in both children and adults
... at the University of Warwick has found that sleep deprivation is associated with an almost a two-fold increased risk of being obese for both children and adults. Early results of a study by Professor Francesco Cappuccio of the University of Warwick's Warwick Medical School were presented to the International ...Adult stem cell research at UB targets damaged hearts
...me due to narrowed coronary arteries adapt to this deprivation by down-regulating metabolism while remaining functionally viable. Previous work in UB's Center for Cardiovascular Research employing the center's novel swine model of hibernating myocardium has shown that restoring normal blood flow to these "hibe...Surprising symbiosis: Glassy-winged sharpshooter eats with friends
...colleagues have discovered that the sharpshooter's deprivation diet is sneakily supplemented by not one, but two co-dependent bacteria living inside its cells. Although insect-bacteria symbiosis is common, this is the first genomic analysis of three partners. In the study, a team of scientists led by TIGR micro...First biomarker for human sleepiness identified in fruit flies
...as amylase, which increases in activity when sleep deprivation is prolonged. Researchers hope to make amylase th...aw subjected the flies to different kinds of sleep deprivation and used microarrays to look for changes in activity in many different genes. Amylase levels consist...