Tag: "demonstration" at biology news

Gene therapy delivery of nerve growth factors reverses erectile dysfunction in animal model

...y do not reproduce, this represents the first-ever demonstration of a long-term treatment for ED that does not rely on the chronic administration of drugs that can have potentially harmful side effects," he explained. ...

A new plant-bacterial symbiotic mechanism promising for crop applications

...for only a small number of these interactions. The demonstration of alternative pathways capable of triggering the nodulation signal in certain rhizobia is promising for future techniques for bringing these bacteria into association with different leguminous plants. It therefore becomes possible to increase agricu...

In mice, drug protects against diabetes and atherosclerosis

...udy, the researchers wrote in their report, is the demonstration that aP2 can be blocked by a small-molecule, oral compound. In turn, they add, the results suggest that targeting aP2 "can lead to a new class of powerful therapeutic agents to prevent and treat metabolic diseases such as type 2 diabetes and atherosc...

Newly discovered antibody may be body's natural defense against Alzheimer's

...that led to this discovery. However, the clear demonstration of the relationship of these scientific findings to clinical benefit in patients requires much more study, the experts say. NewYork-Presbyterian/Weill Cornell is currently leading a six-month Phase II study of IVIG in 24 patients with mild and mo...

Adult stem cells from human cord umbilical cord blood successfully engineered to make insulin

... online this week. Their paper calls it "the first demonstration that human umbilical cord blood-derived stem cells can be engineered" to synthesize insulin. "This discovery tells us that we have the potential to produce insulin from adult stem cells to help people with diabetes," said Dr. Randall J. Urban, sen...

Scripps research team sheds light on long-sought cold sensation gene

... cold sensation. "This study represents the first demonstration that a single gene is responsible for most cool temperature sensation," says team leader Ardem Patapoutian, who has joint appointments with the Department of Cell Biology at Scripps Research and the Genomics Institute of the Novartis Research Foundat...

Dinosaur hearing, listening to muscle noise, quieter cubicles

...ert featuring the Salt Lake City Jazz Orchestra, a demonstration of the Mormon Tabernacle Choir's pipe organ, and a presentation on unusual acoustical effects in the Salt Lake Tabernacle. More details can be found later in the release (see "Salt Lake City Sounds" and "Science of Jazz and Yodeling"). MEDIA INQ...

Biodiesel study targets cleaner air, cleaner engines

...s supporting renewable fuels will help advance the demonstration and use of biodiesel on farms. ...

Mine runoff continues to provide clues to microbial diversification

...ng implications. “More important perhaps is the demonstration of our ability to simultaneously identify a large fraction of an organism’s proteins and to distinguish them from proteins derived from quite closely related organisms,?Banfield said. “This opens the way for detailed studies of how a wide range of mi...

Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease

... effect was more than simply additive). This was a demonstration that stem cell efficacy could be enhanced even without the need for genetic engineering. (The drug, a glycosphingolipid biosynthesis inhibitor, is in a class of compounds called "substrate reduction therapy" drugs.) This part of the study not only re...

Bats prey on nocturnally migrating songbirds

...deed, presence of feathers in diet was no ultimate demonstration of a bird-based diet, although indicative. New innovative approaches were thus necessary for proving the case. But how to study the foraging habits of an elusive predator that chases its favourite prey several hundreds if not thousands of metres abov...

Boosting brain power -- with chocolate

... grey matter flow for two to three hours. "The demonstration of an effect of consuming this particular beverage on cerebral blood flow raises the possibility that certain food ingredients may be beneficial in increasing brain blood flow and enhancing brain function, in situations where individuals are cognitiv...

Cloned mice created from fully differentiated cells, a milestone in cloning research

...nd generation of its own kind. This is the first demonstration that an animal can be derived directly from a fully differentiated cell, report lead researchers Xiangzhong (Jerry) Yang, Ph.D., of the University of Connecticut, and Tao Cheng, M.D., of the University of Pittsburgh, in the journal Nature Genetics. ...

Interaction between lymph and liver cells may affect immune response

...teractions. The discovery of TEHLI is the first demonstration by electron microscopy of the interaction between naïve T cells and liver cells in a living organism, which shows that the liver is an exception to the rule that T cells need to be activated by professional APCs in order to cross the endothelial barr...

Embryonic stem cells do better on bumpy nanoscale mattress

...ighly promising one. This is the first demonstration that the physical topography, using controlled feature dimensions, of cell culture surfaces influences HES cell differentiation and self-renewal, according to the researchers. For HES cells to realize their potential in clinical medicine, they would...

Psst! Coffee drinkers: Fruit flies have something to tell you about caffeine

...rrent spikes when given caffeine. "This is a clear demonstration that Gr66a is functioning in the taste receptor cells and is not a 'general sensor' for bitter compounds, but is required more specifically for the caffeine response," says Montell. "This indicates that flies have different receptors for the respon...

Three-dimensional, miniature endoscope opens new diagnostic possibilities

...cine at MGH describes their prototype device and a demonstration of its use in a mouse model. "This new ultramin.... "While the image resolution we achieved in this demonstration is similar to existing small-diameter endoscopes, with further optimization of the optics it is poss...

Researchers discover new gene responsible for brittle bone disease

...ough the number of affected children is small, the demonstration that they have an inherited form of OI could have a major impact on their future health and quality of life." Study Details In the study, mice were genetically engineered by the Baylor team with the CRTAP gene removed, and then monitored for si...

Zinc plays important role in brain circuitry

... hopes of zincologists. This work provides a clear demonstration that interfering with zinc modulation of a synaptic pathway leads to a significant alteration in the phenotype of the animal." The three scientists added that the finding "puts a nice dent in the zinc armor, which held firm for more than 50 years." ...

Study suggests evolutionary link between diet, brain size in orangutans

...ty of Zurich have found what they say is the first demonstration in primates of an evolutionary connection between available food supplies and brain size. Based on their comparative study, the scientists say orangutans confined to part of Borneo where food supplies are frequently depleted may have evolved through...

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