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Tag: "dementia" at biology news

High estrogen levels associated with dementia in older men

...nal/ana ). As our population ages, the impact of dementia will grow. By the year 2050, some 13 million Ameri...-Asia Aging Study. Participants showed no signs of dementia at baseline in 1991-1993, at which time fasting blood samples were drawn. The researchers measured t...

Viral genetic differences are possible key to HIV dementia

...ical damage." Pillai notes that the issue of HIV dementia is particularly important in regions outside North America and Europe where state-of-the-art antiretroviral medications are not widely available and HIV infection frequently leads to dementia. SFVAMC staff physician Joseph K. Wong, MD, associate ...

In-home sensors spot dementia signs in elderly

...ker that can be used to predict the later onset of dementia in a single individual." They have already begun a larger study to test that theory. Much of the hardware used in the study is simple, widely available and inexpensive. Plus, it's getting smaller and smaller, so it can be deployed in elders' homes ...

Tramiprosate (Alzhemed? preclinical results published in Neurobiology of Aging

... Alzheimer's disease (AD) is a progressive form of dementia associated with specific brain pathologies. It imp...estroys the brain. AD is the most common cause of dementia in our aging population. Almost 5 million individuals in the United States alone currently suffer fr...

Hopkins study suggests commercially available antibiotic may help fight dementia in HIV patients

...ariety of serious infections may also help prevent dementia in HIV patients, according to a test-tube study of...g to Rumbaugh, Tat and gp120 are believed to cause dementia by reducing the expression of a brain chemical called EAAT-2 (excitatory amino acid transporter-2). ...

The urban evolution lab

...y of the protein that is produced, the younger the dementia patient is. Alzheimer's disease Alzheimer's di...is a memory disorder that affects up to 70% of all dementia patients. In Belgium, about 100,000 people suffer from this disease. The disease gradually destroys...

Researchers discover a new genetic cause of Alzheimer's disease

...y of the protein that is produced, the younger the dementia patient is. Alzheimer's disease Alzheimer's di...is a memory disorder that affects up to 70% of all dementia patients. In Belgium, about 100,000 people suffer from this disease. The disease gradually destroys...

Gene therapy 'turns off' mutation linked to Parkinson's disease

...be useful for other diseases of the brain, such as dementia with Lewy bodies, a disease also characterized by Lewy bodies in the brain," Sapru said. The Bohn lab will subsequently test this gene therapy in mouse models of the disease. If the RNA interference approach works in the mouse, a gene therapy based ...

Experimental vaccine protects nonhuman primates when given after exposure to Marburg virus

...ion." While previous studies had linked end-stage dementia due to HIV to the presence of infected and activated immune cells, the nature of neurological changes in earlier stages of the disease, the so-called "chronic phase," were unknown-until now. Using simian immunodeficiency virus-infected models in the...

Immune response to HIV in the brain

...ion." While previous studies had linked end-stage dementia due to HIV to the presence of infected and activated immune cells, the nature of neurological changes in earlier stages of the disease, the so-called "chronic phase," were unknown-until now. Using simian immunodeficiency virus-infected models in the...

Scientists show how thinking can harm brain cells

...ogic functions in diseases such as Alzheimer's and dementia associated with HIV. In an article in the Nov. 1 ...and reduction in size ?is seen in HIV-1-associated dementia and Alzheimer's. In laboratory studies, brain cells and slices were exposed to platelet-activating ...

New research examines genetics of successful aging

..., of Alzheimer's disease, the most common cause of dementia in late life. The study also identified novel genetic regions associated with successful aging, including DYS389 and DYS390, some of which affected men or women, but not both. "Historically women have lived longer than men on average, the prevalen...

Scavenger cells could be key to treating HIV-related dementia

...hages could lead to ways to prevent HIV-associated dementia Bacteria-eating cells that generally fight infection may cause dementia in HIV patients, University of Florida and University of California at San Francisco researchers hav...

Targeting a key enzyme with gene therapy reversed course of Alzheimer's disease in mouse models

...tein clumps in the brain, can precede the onset of dementia by many years. These plaques are formed when enzym...degenerative disorder and the most common cause of dementia among the elderly in the United States, affecting 4.5-5 million adults - 10 times more than those af...

U of MN researchers reverse memory loss in mice

...s predicted that when the transgene expressing the dementia was turned off, memory loss would stop. The result...rpassed their expectations. The mice's symptoms of dementia were reversed--in other words, they regained memory. "Most Alzheimer's disease treatments focus on ...

FDA Warns About Antipsychotic Drugs and Elderly

...reat behavioral disorders in elderly patients with dementia have shown a higher death rate associated with the... treatment of behavioral disorders associated with dementia should have their treatment reviewed by their health care providers. In analyses of seventeen placeb...

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