delivery 2 9

Tag: "delivery" at biology news

Coated nanoparticles solve sticky drug-delivery problem

...d other foreign materials, can block the localized delivery of drugs to many parts of the body, including the ...ues believe this system has great potential in the delivery of chemotherapy, antibiotics, nucleic acids and other treatment directly to the lungs, gastrointesti...

Nanoparticles for delivery of prostate cancer treatment

...ostate Cancer Foundation to expand research on the delivery of a targeted therapy for prostate cancer using na...iposomal nanoparticle vectors ?lipid-covered, gene delivery packets ?to deliver the therapy in animal models of human metastatic prostate cancer. "While we ...

Stem cell therapy shows promise in regenerating damaged muscle in heart attack patients

...of adult stem cells pre-formulated for intravenous delivery by the drug's manufacture, Osiris Therapeutics. P...hrough a standard IV line. Other therapies require delivery to the site of the disease through catheterization or open surgical procedures, but this one was ver...

Anti-fungal drug stops blood vessel growth

...en orally for fungal infection, and therefore oral delivery may work for angiogenesis as well,?Liu notes. ...

Cellulose nanocrystal research could lead to new vaccines, computer inks

...he focus of her research deals with cellulose drug delivery and ink jet printing. Roman experimented with taking cellulose nanocrystals and attaching antibodies to the surface of the crystals. This design enables the nanocrystals to block cell receptors in the body. The process may eventually be used to cr...

A revolution in the monitoring of unborn babies

... is too late to help them. This may involve urgent delivery of the fetus.? The device will be especially helpful in monitoring fetuses whose mothers have medical conditions like diabetes, autoimmune conditions such as systemic lupus erythematosus and Sjogren’s syndrome and obstetric cholestasis. It will als...

Ultrathin films deliver DNA as possible gene therapy tool

... He and his colleagues have also demonstrated gene delivery to cells grown in a dish. In preliminary experim...toolbox of different polymers to fine-tune the DNA delivery properties of their films. Using the layering method, they can control the amount of DNA by adding ...

Can engineered immune cells stop AIDS?

...er the HIV invaders and use their hollow shells as delivery vehicles to insert DNA that will counteract the infection. The "Cadillac" of this gene delivery system is an HIV-based "lentiviral vector," a type of retrovirus that uses the backbone of a virus t...

Living with water scarcity -- world must act now

... water rights and investments in water storage and delivery infrastructure are essential ingredients. The value obtained per drop of water can be improved by pro-poor water technologies, and investments in roads and markets. Multiple use systems ?operated for domestic use, crop production, aquaculture, agro...

Batten down the hatches against HIV

...tumbling block has been the efficient and targeted delivery of RNA into the cells. Researchers led by Hongjie Dai at Stanford University have chosen to use carbon nanotubes as their "means of transport". This has allowed them to successfully introduce RNA fragments that "switch off" the genes for special HI...

Re-analysis of cigarettes confirms tobacco companies increased addictive nicotine 11 percent

...Ferris Wayne. "Cigarettes are finely-tuned drug delivery devices, designed to perpetuate a tobacco pandemic...es the need for continued surveillance of nicotine delivery in products created by an unregulated industry." In an opinion in US vs. Philip Morris USA et. al...

Small molecule dervived from Rb2/p130 could act as cancer therapeutic

...nd does not require potentially dangerous means of delivery like viruses, as do most gene therapies; therefore Spa310 has a good chance to succeed as an anti-cancer therapy. For these reasons, he believes it may be easier to get approval for clinical trials. "Fifteen years after discovering Rb2/p130, our ...

Intravenous nanoparticle gene therapy shows activity in stage IV lung cancer

...ne. "Here we are using a non-viral, non-infectious delivery system," Lu says. The only clinically signific...has been established, Lu says. The nanoparticle delivery system consists of a plasmid gene expression cassette loaded with DNA that encodes the FUS1 protein...

New synthetic self-assembling macromolecules mimic nature

...ructures could have potential applications in drug delivery and gene delivery systems." But more immediate, "These unique block copolymers can be instructive models in underst...

Dual gene therapy suppresses lung cancer in preclinical test

...findings in the mouse studies. The nanoparticle delivery system, which the researchers have used for years, consists of a plasmid gene expression cassette loaded with DNA that encodes either the p53 or the FUS1 protein. This is wrapped tightly in a form of cholesterol to protect it from the body's defense ...

No carrier necessary: This drug delivers itself

...s long challenged scientists to develop innovative delivery systems that keep these drugs intact until reachin...have developed an innovative solution in which the delivery system is the drug itself. They describe for the first time in Molecular Pharmaceutics a drug del...

UTSA researchers examine effects of global warming on Antarctic

...ile long shipping channel that would allow for the delivery of annual supplies to NSF's McMurdo Research Station. On route to Antarctica, the ship passed through 1,700 miles of extensive sea ice cover that surrounds the continent annually. "We now know what the sea ice really looks like as far as its thi...

3-D ultrasound identifies women at risk for impending preterm birth

...ound measurements could identify a preterm risk of delivery within five days of the measurement. "Our results suggest that examining the fetal adrenal gland at the time a woman is evaluated for symptoms of preterm labor, may have major beneficial clinical implications," said first author Ozhan Turan, postd...

Hybrid molecule causes cancer cells to self-destruct

...the molecular partner added to butyrate to improve delivery to the cancer cells often produced unsafe side effects. In some of the less successful experiments, designed to avoid toxic side effects, researchers used innocuous sugar molecules such as glucose to carry butyrate into the cells. The Johns Hopkin...

Penn researchers show how nanocylinders deliver medicine better than nanospheres

... cylindrical-shaped carrier they were able sustain delivery of the anticancer drug paclitaxel to an animal mod...arriers. These findings have implications for drug delivery as well as for better understanding cylinder-shaped viruses like Ebola and H5N1 influenza. This s...

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