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Tag: "delivery" at biology news

U-M researchers use nanoparticles to target brain cancer

...acted to the tumor site. The advantage of this delivery system is the ability to attack the tumor with hig...-M Comprehensive Cancer Center. If nanoparticle delivery proves to be safe in humans, it will allow researchers to re-examine previously developed drugs that...

Telemedicine robots help improve health

...iza to conquer the tyranny of distance and improve delivery of specialist medical care to the bush. Eliza, who began work at Mt Isa Hospital this week, is a creation of the University's Centre for Online Health ?a world leader in telemedicine research. The wireless robots can be wheeled to the bedside o...

Antibody extends life of mice with breast cancer

...f using the antibody as a vehicle for the targeted delivery of drugs to aid cancer diagnosis and therapy. ...

Muscle and bone from an ink-jet printer

...al patterning of stem cell differentiation through delivery of bio-inks with an ink-jet printer will offer the Pittsburgh researchers a whole new level of complexity and control. The custom built ink-jet printer, which was developed at Carnegie Mellon, can deposit bio-inks in virtually any design, pattern...

Carnegie Mellon scientists use 'green' approach to transform plastics manufacturing

...astics for applications ranging from targeted drug delivery systems to resilient paint coatings. The revolutionary improvement in atom transfer radical polymerization (ATRP) now enables large-scale production of many specialty plastics, according to the scientists, whose work appears in a special issue of th...

Rescuing injured hearts by enhancing regeneration

...er injury. Second is the need to develop a safe delivery method. Because FGF1 stimulates angiogenesis, it has the potential for serious side effects if it goes to places other than the heart, possibly promoting tumor growth, for example. And the p38 MAP kinase inhibitor has been shown to damage the liver. ...

Supercomputing equipment to advance the frontiers of computational biology

...nts," with potential applications in targeted drug delivery systems such as drug eluting stents, transdermal patches, and inhalers. To be successful, these simulations must run efficiently and effectively on the latest generation of high-performance computing equipment. The project will help researchers de...

Progress made in HIV vaccine development

...ar HIV strains. "Both approaches operate by gene delivery of customized vaccine antigens that are produced b...ver, DNA may be less potent than vector-based gene delivery strategies. Replication-defective rAd5 has the advantage of targeted, efficient gene delivery and h...

Elusive rust resistance genes located

...ne different sources of resistance to speed up the delivery of new rust resistant wheat varieties." The marker has proven effective in a range of wheats from different backgrounds including from Australia, India, China, North America and the major wheat research centre, CIMMYT. Breeders in Australia an...

Molecules in blood foretell development of preeclampsia

...the short term. The only cure for preeclampsia is delivery of the baby. The condition is estimated to compli...owever, if preeclampsia occurs early in pregnancy, delivery of the baby would result in premature birth, which increases the risk of death, and for such lifelon...

Vaccination with embryonic stem cells prevents lung cancer in mice

...y to cancer. Prof Eaton explained: "We needed a delivery vehicle for GM-CSF and chose STO fibroblasts because they are often used as a 'feeder layer' to maintain these particular mouse embryonic stem cells in their embryonic state. If we had used only ESCs expressing GM-CSF, they might have differentiated...

Intravenous gene therapy protects normal tissue of mice during whole-body radiation

...ng effects of radiation, suggesting it is a viable delivery method," said Dr. Greenberger. "Future clinical studies will tell us whether this therapy can protect people from the deadly effects of radiation." ...

Gene therapy inhibits epilepsy in animals

...ha4 subunits. Therefore, the researchers used gene delivery to alter the expression of the alpha1 subunit to see if this would have an effect on later seizure development. To carry the gene that alters the expression of the protein, they used an adeno-associated virus vector, injected into the rats' brains....

Male contraception: One door opens, another closes

...ing." The next step is to find a more appealing delivery system than shots; both a gel and a matchstick-sized implant have been discussed. But will the contraceptive work as well in humans as in rats? Nothing is guaranteed. Elaine Lissner, director of the nonprofit Male Contraception Information Projec...

How fish mend a broken heart

... to modify this deficiency are underway, including delivery of growth factors or bone marrow-derived cells that may promote [the formation of new blood vessels]…Success in these pursuits or by directly utilizing epicardial cells or their progenitors could prove favorable for encouraging regeneration from mamm...

St. Jude announces breakthrough in eye cancer treatment

...ith nutlin-3 represents the first example of local delivery of a targeted chemotherapy drug for any childhood ...cific molecule inside a growing cancer cell; local delivery is the placement of a drug at the site of disease, rather than systemic treatment. In systemic treat...

Breathing easy: When it comes to oxygen, a bug's life is full of it

...moths and grasshoppers. Krogh’s interest in oxygen delivery led him later to study blood perfusion in mammalian capillaries, for which he was awarded the Nobel Prize in 1920. But the advent of synchrotron x-rays, an advanced form of x-ray scan, has recently allowed scientists to learn much more about how inse...

Vitamin D deficiency widespread during pregnancy

...can women and nearly half of white women tested at delivery had levels of vitamin D that were too low, even though more than 90 percent of them used prenatal vitamins during pregnancy," said Lisa Bodnar, Ph.D., M.P.H., R.D., assistant professor of epidemiology at the University of Pittsburgh Graduate School o...

CSIRO imagery shows Outer Great Barrier Reef at risk from river plumes

...e Earth and CSIRO has invested in fast information delivery systems. The images answer many of the questions posed in the article 'Cattle, Crops and Coral: Flood Plumes and the Great Barrier Reef' from the 2006 NASA EOS Annual Report. ...

Stem cell therapy shows promise for rescuing deteriorating vision

... "The idea was to test the cells as a continuous delivery system" to shuttle an agent known as glial cell li...ars. The idea was to use the cells as a continuous delivery system, but we found they work quite well on their own." Lund has experimented with other cell ty...

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