Researchers design pulsed mircrojet system to deliver protein drugs without pain or bruising
... Sciences. The effort to create needle-free drug delivery systems is driven by a combination of factors, inc...needle injections are performed every year for the delivery of vaccines and protein therapeutics such as insulin, growth hormone and erythropoietin, a red blood...Gut research yields new anti-cancer approach
...le out this approach as once feared. With new drug delivery technologies that help drugs target only cancer cells, we are very excited about the potential of this line of work." ...Brain's reward circuit activity ebbs and flows with a woman's hormonal cycle
...on profile than women during both anticipation and delivery of rewards. For example, men had more activity in ... cortex (executive hub) area at the time of reward delivery compared to men. ...Investigating the measles virus as a tool to kill multiple myeloma
...mine the best way to manufacture a safe biological delivery mechanism, and finally, to clinicians who understand the science and develop guidelines by which the study is conducted and correctly carried out. With this outstanding team, we can truly focus on achieving the greatest benefit for the patient.? Th...Biodegradable microspheres deliver time release vaccines, stimulate different immune response
A new vaccine delivery system using microspheres of a biodegradable polym... for booster vaccinations, by developing a vaccine delivery system that released the vaccine into the system slowly over time. They chose a biodegradable polym...Study shows dramatic increase in Caesarean sections
..., said that even after adjusting for pregnancy and delivery complications and sociodemographic factors, the increases were significant. Women in 1999-03 were twice as likely to have a caesarean section, than women in 1984-88. "The figures show that what we call elective or planned caesareans have risen fr...Iowa State scientists demonstrate first use of nanotechnology to enter plant cells
...hnology, creating a powerful new tool for targeted delivery into plant cells. The research, "Mesoporous Sili...ique feature provides total control for timing the delivery The team’s first attempt to use the porous silica nanoparticle to deliver DNA through the rigid ...Percutaneous aortic valve replacement safe, successful in high-risk patients
...ve replacement is performed by threading a special delivery catheter through the femoral artery in the groin and into the aorta in a direction opposite, or retrograde, to the normal flow of blood. Once the catheter is properly positioned in the opening of the aortic valve, it is pulled back to release the Cor...UCLA AIDS Institute researchers find a peptide that encourages HIV infection
...des in gene therapy using HIV-based vectors as the delivery method. "Although it may seem counterintuitive to value or even study a peptide that increases the ability of HIV-1 to enter a broad range of human cells, retroviral vectors are currently being explored as vehicles for gene therapy," the authors w...Simple home spit test to spot deadly pre-eclampsia
... the urine. While there is no cure, other than the delivery of the baby and removal of the faulty placenta, early detection and management of the problem can have a big impact on patient outcome. ...New designer lipid-like peptide with lipid nanostructures for drug delivery systems
...ovide new strategies for the encapsulation and the delivery of biological active materials. They detailed the...the encapsulation of water-insoluble drugs and the delivery of biological active materials.” Currently, many anticancer drugs are difficult to deliver to p...Treating HIV in war zones -- Public health emergencies need rapid advice from WHO
..."the key elements of contingency planning for care delivery in conflict settings are not resource-intense and we believe they can generally be applied to most care programmes." Citation: Culbert H, Tu D, O’Brien DP, Ellman T, Mills C, et al. (2007) HIV treatment in a conflict setting: Outcomes and experien...Blood-brain barrier breached by new therapeutic strategy
... invasive procedures that result in only localized delivery around the site of injection. The new research pro...ers are now trying to improve the efficacy of this delivery system and to make a stable form of siRNA that might yield even better results....UCF nanoparticle offers promise for treating glaucoma
... of Central Florida is proving promising as a drug delivery device for treating glaucoma, an eye disease that ...developed the research on using nanoparticles as a delivery mechanism for the compound after supervising a student summer project at UCF. Duke University underg...Bacteria ferry nanoparticles into cells for early diagnosis, treatment
...erial can be selected from many choices, this is a delivery system that can be tailored to the characteristics...lly available polystyrene nanoparticles makes this delivery system much simpler to implement than previous alternatives," Bashir said. This new delivery syst...Penn researchers link cell's protein recycling systems
...umulation of defective proteins, HDAC6 facilitates delivery to the autophagy-lysosomal system for degradation. “That’s how we think HDAC6 links the two systems,” says Taylor. Dr Taylor and his team are now testing the ability of HDAC6 to prevent neurodegeneration in several mouse models, including motor ne...Millions of children denied drug that costs less than $3 a year
... if fully integrated within a community healthcare delivery system, which should provide not only reliable supplies of drugs, with adequate facilities for storage and dispensing, but also educational programmes for health practitioners and the general population, he concludes....Gene therapy delivery of nerve growth factors reverses erectile dysfunction in animal model
...get nerve cells. According to Dr. Glorioso, HSV delivery of GDNF or neurturin presents a potentially important new approach for the treatment of ED. "Because the herpes virus persists in the nerve cell for as long as it is alive and nerve cells typically do not reproduce, this represents the first-ever dem...Enzyme delivered in smaller package protects cells from radiation damage
...ious studies showing that intravenous gene therapy delivery of the enzyme manganese superoxide dismutase (MnSOD) could protect mice from whole body irradiation, and in preparation for a potential clinical trial of systemic MnSOD in humans, the University of Pittsburgh and Stanford researchers, led by Joel S. ......red on video the intracellular version of a postal delivery service. Reporting in the journal Biochemical and Biophysical Research Communications (BBRC), bioengineering researchers at UC San Diego published videos of a key message-carrying protein called paxillin moving abruptly from hubs of communication and...