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Tag: "define" at biology news

UT Southwestern researchers find gene mutation that leads to 'broken hearts'

...e said. One of the goals of this research is to define the genetic blueprint for how the heart forms. In order to do that, the UT Southwestern scientists engineered fruit flies whose hearts glow by expressing a gene coding for green fluorescent protein specifically in the heart. "This fly with a glowing ...

AIDS-related cognitive impairment exists in two separate forms

... Most researchers use gene or protein "chips" to define cancer processes, but researchers at Thomas Jefferson University in Philadelphia took a novel approach using a micro-RNA (miRNA) chip to help them understand how colon cancer develops. They found a distinct "signature" in the expression of miRNAs tha...

Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers

... Most researchers use gene or protein "chips" to define cancer processes, but researchers at Thomas Jefferson University in Philadelphia took a novel approach using a micro-RNA (miRNA) chip to help them understand how colon cancer develops. They found a distinct "signature" in the expression of miRNAs tha...

Study finds 60 new genes controlled by DNA snippet

Researchers worldwide are seeking to define ancient sections of our genetic code that may soon...s to those already known, authors of the study now define the functional mammalian CarGome as 161 sequences, a 55 percent increase from the old definition. ...

A Jekyll and Hyde of cytokines: IL-25 both promotes and limits inflammatory diseases

...s known as whipworms, the researchers were able to define IL-25's role in promoting type 2 inflammation to fight infection. In mice that lack the ability to produce IL-25, researchers saw a dramatic reduction in the ability to mount a type 2 response that eradicates the parasites. Furthermore, in the abse...

Most human-chimp differences due to gene regulation ?not genes

...ur evolutionary history, these new results help to define exactly which regulatory factors may be important, at least in certain tissues. This helps open the door to a functional dissection of the role of gene regulation during the evolution of modern humans." To measure changes in gene expression from di...

Genome changes tracked during multiple myeloma initiation, progression and treatment

...r genes. These amplification and deletion patterns define new disease subgroups of MM that are characterized by varied dysregulation of distinct cancer-relevant genes and can be correlated with different clinical outcomes. Importantly, several candidate genes identified in this study possess broad clinical ...

Mayo Clinic researchers challenge sepsis theory

...te efforts to block the poisons." The researchers define a new "first step" that initiates the sepsis syndrome cycle. In this step, a critical receptor for bacterial poisons and for some of the body's own substances is liberated from "natural suppression." Once free to function, the receptor can trigger th...

A new way of looking at molecular motors

...nd tail evolved together. That finding helped them define some of their new categories. Organisms employ all three types of motors at the same time, but in different proportions. For example, yeast uses six kinesins, five myosins, and one dynein while mammals have genes for more than 40 kinesins, 40 myosi...

Advanced genomics and proteomics improve the diagnosis and treatment of a deadly lung disease

...eams are scattered in a way that helps researchers define the overall structure of the crystallized protein, as was the case with Dicer. Knowing how the atoms of specific molecules are arranged permits researchers to tease out their functional features and show how they go about their business inside a cell...

Molecule does more than slice and dice RNA

...eams are scattered in a way that helps researchers define the overall structure of the crystallized protein, as was the case with Dicer. Knowing how the atoms of specific molecules are arranged permits researchers to tease out their functional features and show how they go about their business inside a cell...

Bocavirus infection may be associated with pneumonia in Thailand, especially in children

...ia patients of all ages is a unique opportunity to define the epidemiology of new viruses, "says Sonja Olsen, Acting Director of the IEIP and one of the researchers. The researchers tested nasopharyngeal swab specimens collected from hospitalized pneumonia patients in rural Thailand between September 1...

Terahertz imaging may reduce breast cancer surgeries

...dity. Thus, there is a clinical need to accurately define the margins of the tumor during surgery. ...

'Uniquely human' component of language found in gregarious birds

...plexity is described by the Chomsky hierarchy, "to define the boundaries between humans and other creatures," said Margoliash. "Now we find that we have been joined on this side of that boundary by the starling. It should no longer be considered an insult to be called a bird brain." Although they are not...

Three new species of lemurs identified

...r chromosome profiles ?the methods usually used to define species. These findings have important implications, as a better knowledge of lemur species characteristics will provide the basis for better conservation programmes for these endangered animals. An international team comprising researchers from Mad...

Picking apart how neurons learn

...hns Hopkins researchers have used mouse mutants to define critical steps involved in learning basic motor skills. The study focuses on the behavior of two proteins and the specific steps they take to control a neuron's ability to learn by adapting to signals from other nerve cells. The findings, published...

Bones from blood: Scientists aim to break new ground on fractures

...olation and expansion to the wider environment and define potential barriers and areas of weakness in their use. They will consider questions such as safety and standards, commercial viability, potential investment, consensus amongst scientists and clinical distribution. Dr Stephen Holland and Professor To...

Picking particles faster than one at a time

...ely qualitative term, unfortunately, but if we can define it so that image-processing software makes only the best choices, we will have a powerful new tools for biology." Adiga says, "Particle-picking algorithms are a small part of a larger goal of mapping the healthy constituents of cells against diseas...

Scientists crack code for motor neuron wiring

...pools." Using antibodies to the Hox proteins that define spinal motor neurons, Dasen and colleagues mapped the timing and location of each of the Hox proteins expressed by motor neurons that project to the wing in chick embryos. "It became clear that these proteins weren't randomly expressed, but were expr...

Technique offers new view of dynamic biological landscape

...les of previously uncharacterized proteins, and to define how biochemical pathways and proteins interact wit...echnique to a "mini array" of 442 yeast genes that define a biological pathway called the early secretory pathway. This compartmentalized, interconnected path...

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