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Tag: "deficits" at biology news

Iron Deficiency Sparks Dramatic Changes In Gene Expression

...nging symptoms from fatigue,weakness and cognitive deficits to serious heart complications anddevelopmental disorders. Iron deficiency also contributes to thepathology of hereditary blood disorders, Parkinson's disease andcertain cancers and develops during a number of chronic diseases, theresearchers said.Un...

Weill Cornell Research Reveals Secrets Of Trafficking Within Cells

...s a kind of cellular fine-tuning, and we know that deficits in this fine-tuning can wreak havoc on health," said Dr. Timothy Ryan, Professor of Biochemistry at Weill Cornell Medical College. "It's well known in obesity, for example, that even a tiny change in metabolic rate results in someone becoming obese."...

Special Imaging Study Shows Failing Hearts Are 'Energy Starved'

... Hopkins researchers have found substantial energy deficits in failing hearts. The findings, published in the January 18 issue of the Proceedings of the National Academy of Sciences, confirm what many scientists have conjectured for years about heart failure, and suggest new treatments designed to reduce ene...

Mystery Blood Vessel Disorder Implicated In 'Mini' Strokes

...acunar strokes can also cause cognitive and memory deficits that resemble Alzheimer's disease. According to the authors, physicians who encounter patients with small vessel disease should look for evidence of dolichoectasia. "If dolichoectasia is present, you should look for an associated abdominal aortic an...

Brain-injury rehabilitation depends on acetylcholine circuitry

... particularly intriguing in light of the fact that deficits in the system have been associated with aging, Alzheimer's disease, and traumatic brain injury. Researchers have long believed that rehabilitation from brain injury causes a rewiring, or plasticity, of brain circuitry--called a "reorganization of co...

Grasping metaphors: UC San Diego research ties brain area to figures of speech

...gent and mentally lucid, the patients showed gross deficits in comprehending such common proverbs as "the grass is always greener on the other side" and "an empty vessel makes more noise." Asked to explain the sayings, the patients tended give responses that were literal. The metaphorical meaning escaped them...

Researchers make surprise discovery that some neurons can transmit three signals at once

...ke epilepsy, schizophrenia and depression, involve deficits that prevent normal inhibition of cells. Dr. Kandler's research could eventually provide insight into the biological cause of these disorders and help to identify novel approaches for prevention and treatment. Further study could have particular impl...

Penn Researchers Use Robotic Surgery

... in half. This can result in speech and swallowing deficits for patients. "The research we've done to date suggests that TORS has great potential to improve the way we treat head and neck cancer patients," said Bert O'Malley, Jr., MD, Chair of PENN's Department of Otorhinolaryngology/Head and Neck Surgery. "W...

Two new retroviruses—transmitted from animals—identified

... in half. This can result in speech and swallowing deficits for patients. "The research we've done to date suggests that TORS has great potential to improve the way we treat head and neck cancer patients," said Bert O'Malley, Jr., MD, Chair of PENN's Department of Otorhinolaryngology/Head and Neck Surgery. "W...

Investigating 'brain shrinkage' in alcoholics

...chieve long-term abstinence in spite of persistent deficits in decision-making. "There is accumulating eviden...idual proteins that might play a role in cognitive deficits as well as recovery and repair of the brain. Together we can develop strategies for public education...

'Shifty-eyed' Monkeys Offer Window Into Brain's Social Reflexes

...r individual is looking or paying attention.' Such deficits not only cause problems for autistic children in everyday social interactions, said Platt, but also in teaching them. 'When you're teaching another person, you often engage with them in 'joint attention,' where you establish attentive contact and und...

Energy management in cells may hold key to cancer defense

...r "gas gauge," AMPK, can turn around and alter any deficits in the cell if it is turned on by the kinase LKB1. In this JBC study, we wanted to see if AMPK could also be turned on by something besides LKB1." "We decided to work with cervical and lung cancer cells because LKB1 is absent from the cellular path...

Past droughts geographically widespread in the West, according to tree-ring data

...e Colorado River would be available to make up for deficits on the Salt and Verde rivers during times of extreme drought," said Charlie Ester, Salt River Project's manager of Water Resource Operations. "The bottom line is that the Upper Colorado Basin and the Salt and Verde basins work together as one entire ...

Targeting a key enzyme with gene therapy reversed course of Alzheimer's disease in mouse models

...f treatment, mice that had already suffered memory deficits could learn and remember how to find their way through a water maze," says co-author Robert Marr, a post-doctoral researcher in Verma's lab. "It appears that these mice can come back from a very severe level of disease progression," adds first autho...

Brain activity related to processing faces is similar in people with, without autism

...cal for the appropriate generation of actions show deficits in autistic individuals. In addition, we wanted to see if these deficits were further compounded by the presence of social cues on which executive decisions had to be based,...

Recreating 'Flowers for Algernon' with a happy ending

...ass of cholesterol drugs, to reverse the attention deficits linked to the leading genetic cause of learning disabilities. The Nov. 8 issue of Current Biology reports the findings, which were studied in mice bred to develop the disease, called neurofibromatosis 1 (NF1). The results proved so hopeful, that ...

UCLA imaging study of children with autism finds broken mirror neuron system

...ional mirror neuron system may underlie the social deficits observed in autism," said Mirella Dapretto, lead author and assistant professor in residence of psychiatry and biobehavioral sciences at the Semel Institute for Neuroscience and Human Behavior at UCLA and the David Geffen School of Medicine at UCLA. ...

New compound stops brain cell degeneration in Alzheimer's disease

...mpound also attenuated Alzheimer's-like behavioral deficits in the mice that are due to injury to the hippocampus. While previous research by the authors and many other investigators in the field has linked plaques, tangles and neuronal injury to synaptic dysfunction and cognitive decline, the direct linkage...

Attention shoppers: Researchers find neurons that encode the value of different goods

...howed that lesions to the OFC can result in choice deficits such as eating disorders, compulsive gambling, and.... "A concrete possibility is that various choice deficits may result from an impaired or dysfunctional activity of this population, though this hypothesis rem...

Engineered mouse mimics cognitive aspects of schizophrenia

...mice did show the same kinds of specific cognitive deficits seen in human schizophrenics. In tests using mazes, the animals showed deficits in "working memory"--the temporary storage of information required for a task. The animals also show...

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