defects 2 8

Tag: "defects" at biology news

New protein implicated in autism

...mmediate relatives, leading to the suggestion that defects in CADPS2 function might predispose individuals to develop autism. ...

Natural polyester makes new sutures stronger, safer

...tient, which would spare children with heart valve defects from undergoing repeated surgeries. Tests of the device in animals have shown promise. "We've been able to show we can produce a valve scaffold that functions better and can grow with the animal," Williams said. "If the valve can grow with the pat...

Statin plus cancer drug deliver combo punch to brain cancer cells

...n known to stunt fetal development and cause birth defects in humans and animals. Its connection to anti-cancer efforts grew out of later insights into its blockage of hedgehog, which gets its name from spiky hairs that develop on fruit flies lacking the signal. "We already knew from earlier research that...

UCLA scientists design masks to hide genetic mutations from cell

...echnique prevents the cell from seeing the genetic defects and restores splicing to the correct location in the gene. IMPACT: The laboratory findings suggest a powerful new approach for treating cancer and other diseases caused by genetic mutations. The researchers?next step will be to test their findi...

Scientists discover a new risk factor for Alzheimer's

...George Hyslop and his team reasoned that inherited defects in some of these proteins might cause more APP to be shunted into endosomes, causing more amyloid-beta to be made, thereby increasing risk for Alzheimer's. When the team investigated these genes, only SORL1 was associated with an increased risk of Al...

Proteins important in Alzheimer's, Parkinson's disease travel in the slow lane

...ny neurodegenerative diseases are characterized by defects in this process. Of particular interest is a group... up new avenues for investigating axonal transport defects in neurodegenerative diseases," concludes Roy....

New molecular pathway could reveal how cells stick together

...imilar work knocking out MMP in flies. "One of the defects in MMP mutants is in their ability to control cell adhesion," she said. Many tissues undergo remodeling as the flies grow and develop, but at least one, the breathing tubes, do not develop properly in the mutant flies. Page-McCaw calls it a "cellular...

Tumor-suppressor gene is critical for placenta development

...hey also predisposed to miscarriage? Do Rb-related defects in the placenta cause learning or physical abnormalities? We are investigating these questions now." Scientists know that the protein encoded by the Rb gene, the Rb protein, plays an important role in regulating how cells grow. But exactly how it ...

Gene elevating breast cancer risk also causes prostate cancer

...it may be that there still are other PALB2 genetic defects accounting for heritable breast and prostate cancer susceptibility. Recent results also imply that PALB2 might be a cancer susceptibility gene in other populations as well. It's been shown that two of the mutations identified in Fanconi anemia patien...

New recommendations against a major opportunistic infection -- cryptococcosis

...disease. Finally, the patients having neurological defects and/or abnormal consciousness, or abnormal neuroimaging at the time of diagnosis, have a worsened prognosis for survival. Along with these different factors, the researchers studied the impact of the initial "fungal load" (the quantity of fungi in...

Veterinary scientists explore poultry virus as cancer killer

...feron antiviral systems, he said. NDV utilizes the defects to replicate in the diseased cells. The replication of NDV leads to the death of the cancer cell by a process called apoptosis - also known as programmed cell death or cell suicide- in the cell. ...

Researchers develop marker that identifies energy-producing centers in nerve cells

...escent marker protein may shed light on brain cell defects believed to play a role in various neurological diseases. The researchers describe how this marker works in mice in the December 20, 2006, issue of The Journal of Neuroscience. The marker gives scientists the first-ever opportunity to distinguish be...

UCLA study uncovers clues for why Graves' disease attacks the eyes

...nstitute and Harbor-UCLA Medical Center discovered defects in the infection-fighting T-cells of GD patients?immune systems. Reported March 1 in the Journal of Immunology, their study may deepen understanding of how the autoimmune disorder damages the body and offer a new target for treating the disfiguring ...

Intelligent materials to regenerate bone tissue

... United States suffer from disorders in or serious defects of some part of their bone structure. Operations involving grafts or implants, required to mitigate the damage, depend decisively on the materials used. The European Nanobiocom project, led by INASMET-Tecnalia with the help of others, is working on ...

Thymus transplants gives hope to babies with fatal immune disease

... also can have a range of problems including heart defects and unusual facial features. However, about 1 percent of these babies have no thymus at all, a situation that ends in death, usually by infection. These are the patients who are candidates for thymus transplantation. "We want people to know that w...

DNA repair proteins monitored at double-strand break

...o of these repair proteins, ATM and NBS1, leads to defects in double-strand break repair by disrupting the signaling processes triggered by the break. "A lack of functioning ATM causes ataxia-teleangiectasia, a disease that causes a variety of debilitating problems, such as neurodegeneration, cancer and sens...

Molecule that destroys bone also protects it, new research shows

...hting infections. In fact, humans with neutrophil defects usually lose all their teeth by the time they are 20 due to severe periodontal disease. "It turns out that IL-17 is really important in regulating neutrophils by causing other cells in the vicinity to recruit these infection fighters to the infect...

Premature births may be linked to seasonal levels of pesticides and nitrates in surface water

... annual meeting, Dr Winchester reported that birth defects peak in Indiana and in the United States as a whole during April through July, the same months as pesticides and nitrates reach their maximum concentrations in surface water. This year's presentation expands upon that work. "A growing body of ev...

New vaccine prevents CMV infection and disease in mice

... herpes virus, is the leading viral cause of birth defects and a serious problem in patients with compromised immune systems. The body’s natural immunity doesn’t protect against infection by the virus, estimated to be present in 50 to 75 percent of all adults. “Until now, scientists haven’t been able t...

Mutating the entire genome

...-gene portions of DNA control genes to cause human defects and diseases. Credit: Sen Wu, University of Utah ...methods can. That makes it easier to find out what defects or diseases arise due to such mutations, and thus what the DNA does normally. They devised a m...

1 2 3 4 5 6 7 8 9