defects 2 2

Tag: "defects" at biology news

Scientists find microRNAs regulate plant development

... changes were correlated with dramatic development defects in leaves, roots, and flowers, showing that microRNA-mediated regulation of ARF17 is essential for normal plant development. Bonnie Bartel notes that "we have known for several years now that microRNAs regulate genes implicated in auxin responses; w...

Researchers feed tiny pills of RNA to planarians to identify genes essential for regeneration

...screened 1,065 planarian genes with RNAi. Specific defects were associated with 240 of the genes that were silenced. About 85 percent (204) of the 240 genes are shared by the genomes of other species, including humans, according to Sánchez Alvarado. The researchers found that 145 of the silenced genes affec...

Sandia completes depleted uranium study

...cers, and neurocognitive effects, as well as birth defects in the progeny of exposed veterans and civilians. ...l, examined the potential risk of DU-induced birth defects in the children of exposed individuals, and provided a more detailed analysis of the dispersion of D...

Micro-molecule plays big role in birth defects

...t may help doctors better understand cancer, birth defects and other health problems. The finding, which wil...nd limbs were visibly smaller. "Many of the birth defects we see in people are mimicked by the defects we've seen in this mouse model," said Xin Sun, Ph.D., a...

Gap-climbing fruit flies reveal components of goal-driven behaviors

... analysis, the researchers found mutant flies with defects specifically in deciding whether to cross, another group of mutants performing the correct motor program at a wrong position, and still another group of mutants performing climbing actions at the correct position but without one of the three motor co...

Elderly mice yield clues to the process of growing old

... drugs that could prevent the gathering of genetic defects in mitochondrial DNA, genetic material that reside...neered to have fewer than normal mitochondrial DNA defects or improved mitochondrial function may pave the way for strategies to retard aging. "The idea would ...

Defect in gene causes 'neuralgic amyotrophy'

...olecular puzzle of this disease by identifying the defects in the gene responsible for this disorder. Neuralgic Amyotrophy, a painful disorder of the nervous system Hereditary Neuralgic Amyotrophy (HNA) is characterized by repeated attacks of pain in a shoulder, arm, and/or hand, followed by total or p...

Research suggests fitness of Florida panthers improved by limited breeding with Texas animals

...n very high numbers. Once you get new blood, those defects disappear from the population. Hybrids are better than inbred animals." The paper also notes that "hybrid cats are beginning to expand their ranges to areas previously thought to be unsuitable," meaning environments "once supposed to be unable to su...

Huntington's cure in flies lays groundwork for broader treatment approaches

...in. "And we are not yet sensitive to detecting the defects in those other tissues." Rather than focusing treatment strategies on single genetic pathways, then, Yin believes a promising alternative might be to simultaneously target a cocktail of gene-induced activities - all of which are set in motion, for e...

Weight control protein may yield antiobesity drugs

...wing to voracious feeding. The mice also exhibited defects in the leptin signaling pathway in brain cells of the hypothalamus, they report. Earlier studies have found that mice lacking leptin show marked obesity that is restored following leptin treatment, Rui said. However, obese animals, with high blood c...

No small feat: First ever gene therapy success for muscular dystrophy achieved

...erapeutic benefit if it is able to reverse genetic defects in every cell of the body's 600 muscle groups. By using a miniature gene, similar in function to the one defective in CMD, and applying a newly developed method for "systemic" gene delivery, the Pitt researchers have shown that gene therapy for musc...

Fish and chips: A fast track to understanding blood development

...ng the expression of 14 of these genes resulted in defects in how blood cells developed in zebrafish. The next step is finding out how these 14 genes are involved in the development of blood cells in mammals, as well as how to harness the cells' ability to self-renew, or multiply. In the future, the techniq...

Tiny avalanche photodiodes target bioterrorism agents

...solar-blind APDs is the high number of crystalline defects present in the AlGaN semiconductor material. However, researchers at the Center for Quantum Devices have been able to realize high-quality AlGaN so as to demonstrate avalanche gain in the solar-blind region. Northwestern's results were presented rec...

Defective Gene Linked to Two Inherited Immune Deficiencies

...that it is likely that as yet unidentified genetic defects underlie CVID and IgA deficiency in those cases wh...osed to IgA deficiency and CVID. “A test for TACI defects would enable the diagnosis of more children and their relatives with these immune deficiencies,?says...

Agreement will speed research on microbicides for women

...that it is likely that as yet unidentified genetic defects underlie CVID and IgA deficiency in those cases wh...osed to IgA deficiency and CVID. “A test for TACI defects would enable the diagnosis of more children and their relatives with these immune deficiencies,?says...

Biologists Crack Genetic Code for Specialized Spider Silk

...that it is likely that as yet unidentified genetic defects underlie CVID and IgA deficiency in those cases wh...osed to IgA deficiency and CVID. “A test for TACI defects would enable the diagnosis of more children and their relatives with these immune deficiencies,?says...

Baby's genes affect mom's cholesterol levels

...ho are advised not to have children due to genetic defects in lipoprotein metabolism. Because their fetuses can compensate for their defects, the women may actually be able to bear children without complications. ...

An essential regulator of body weight revealed

...r parts of the brain to reduce appetite. Mice with defects in POMC neurons eat excessively and become obese. The other neurons that make up the arcuate nucleus are NPY/AgRP neurons, named for two proteins they produce, neuropeptide Y (NPY) and agouti-related protein (AgRP). Researchers have long suspected ...

Study hints at role of stem cell genes in testicular, breast cancers

...o identify the genetic missteps that lead to birth defects and infertility. As part of this research, the team had determined that the four genes ?OCT 4, NANOG, STELLAR and GDF3-- play a role in prompting human embryonic stem cells to develop into primordial, or earliest-stage, germ cells. Three of these ge...

Gene therapy reverses genetic mutation responsible for heart failure in muscular dystrophy

...girdle muscular dystrophy, or LGMD. In human LGMD, defects in a muscle cell membrane protein known as delta-sarcoglycan lead to severe damage and weakness to muscles, particularly around the hips and shoulders--hence the name "limb girdle"-- as well as in the heart. Like humans, hamsters with this particular...

1 2 3 4 5 6 7 8 9