Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats
...herapy might be used to "turn down" the mechanism, decreasing cholesterol levels and heart disease risk, explained Spiegelman, who is also a professor of cell biology at Harvard Medical School. Saturated fats are found in fatty cuts of meat, whole-milk dairy products, butter, and palm and coconut oils; they ar...VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
...sed genes to be turned on more in one strain while decreasing expression of the same gene in the other mouse strain. Such differences are thought to be related to the mechanisms underlying the different behaviors that the B6 and D2 mice show with alcohol. Researchers also determined whether genes with changes ...Live fast, die young true for forests too
...forest could lead to more rapid turnover of trees, decreasing the average age of trees. In the long run, such changes might affect wildlife populations that prefer younger or older forests, said van Mantgem. Stephenson and van Mantgem pointed out that increased dominance by younger trees could also lead to cha...Canadian youth 4th highest in international obesity study
...y. "Increasing physical activity participation and decreasing television viewing should be the focus of strategies aimed at preventing and treating overweight and obesity in youth." The study is based on statistics gathered in 2001-2002 by the World Health Organization's Health Behaviour in School-Aged Childre...Sickle cell and protection against malaria
...gainst mild malaria increased up to 60% at age 10, decreasing to 30% in older children. Research into malaria has yet to yield an effective vaccine but this work may provide some insights for such research. The authors suggest mechanisms by which HbAS could affect immunity, for example, accelerated acquisition...Undesirable expatriates: Preventing the spread of invasive animals
...with introductions peaking in the 19th century and decreasing thereafter. This decline can be attributed to a reduction in immigration following WWI and increased U.S. regulations on wildlife imports. Conversely, North American introductions to Europe have been on the rise throughout the 20th century as more A...Gladstone investigators discover how resting T cells avoid HIV infection
... to it and accelerating its destruction as well as decreasing is production. These effects of Vif were so complete that no A3G was left in infected activated CD4 T for incorporation into the new viral particles. Thus, this antiviral action of A3G that only occurs in activated T-cells can be overcome by Vif. Th...Research shows smoking adds a decade to reproductive age of IVF patients
...he cause of subfertility, with the live birth rate decreasing by 2% for each additional year of age. "In all subgroups smokers had a lower delivery rate per treatment cycle than non-smokers," Dr Lintsen said. "The live birth rate for smokers was 28% lower than that of non-smokers. This was most marked in women...Unlike other mammals, newborn dolphins and orcas stay active 24/7 during first months of development
... or sleep behavior at birth with amounts gradually decreasing to adult levels. In fact, past findings that sleep deprivation for two to three weeks can be lethal in rats and flies has led to the belief that sleep is critical for the development of brain and body and serves a vital function in adults. The abili...Study Finds Moderate Hypothermia A Safe Treatment For Traumatic Brain Injury In Kids
...ced in the groin and armpit areas are effective in decreasing temperature. In addition to safety, mortality and complications during the treatment protocol and during hospitalization, the study also assessed functional and cognitive outcome in these children with severe traumatic brain injury. After severe TB...Blink, and the brain misses it
...ientists discovered that visual sensitivity begins decreasing immediately before a blink, but the brain mechanisms underlying this process have until now remained unclear. As they report this week, Davina Bristow and a team of scientists at University College London led by Dr. Geraint Rees may now have found a ...Study: Harmless virus kills some cancers
...d to its ability to slow cell-cycle progression by decreasing cancer cell proliferation rates and causing growth arrest. In this study, the team first used HPV infected epithelial cells and normal human epithelial cells, which are natural hosts for both AAV2 and HPV. In cultures infected with both AAV2 and HPV...Fundamental discovery -- Bone fracture
...is. Bone fracture is one of the leading factors in decreasing quality of life for the elderly. "Cancer and heart disease can kill you but bone fracture and arthritis make you miserable," he said. "Once a serious bone fracture occurs, then quality of life goes down. Less than one-third of elderly women who have ...Engineered molecule amplifies body's immune response
...low for much lower doses of interferon to be used, decreasing cost and side effect profile. In terms of diagnosis, it may be possible to screen patients for the level of Stat1 responsiveness to interferon, and if found to be low, that would make them candidates for a strategy to improve Stat1 responsiveness usi...Sugar helps control cell division
...ntrast, our experiments show that by increasing or decreasing the amount of sugar attached to proteins, the cell cycle is disrupted and isn't salvageable unless O-GlcNAc levels are fixed." In experiments with human cells and mouse cells, Slawson and his colleagues showed that preventing a cell from removing th...... Increasing the salt concentration in the cell or decreasing the salt concentration around the cell leads to an influx of water. This principle is known as osmosis. Cells activate various channels to remove excess water and salt or osmotically active particles from the cell. Tomassen studied cells that are h...Old drug shows new promise for Huntington's Disease
...o results suggest that Clioquinol has an effect of decreasing the symptoms of Huntington's, its pathology, and perhaps even the actual production of the toxic protein." However, he noted, "the drug's mechanism of action remains unclear." The clearer the mechanism of the drug, he explained, the better the chanc...Researcher at UGA College of Veterinary Medicine identifies new way of combating viral diseases
...the viruses to exit the cell, thereby dramatically decreasing the ability of the virus to spread rapidly and produce infection," Hodge said. Because these viruses depend heavily on this exit pathway, they probably would not be able to find another route out of the cell. This suggests that Rab9 and other compon...UNC scientists discover new role for protein as fundamental inhibitor of cell movement
... a likely target for new drug development aimed at decreasing tumor metastasis, or spread, throughout the body. "I was ecstatic to see these results and to discover that it also regulates the fundamental process of cell migration," said Dr. Tina Leisner, associate professor of pharmacology at UNC and the study...Researchers find gland that tells fruit flies when to stop growing
...izes than usual. Suppressing the gland's growth by decreasing insulin signaling allowed larvae to grow larger than usual before entering the pupal stage that precedes adulthood. Mirth and her colleagues, UW biology professors Lynn Riddiford and James Truman, surmised that size assessment had to be accomplished...