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Tag: "decoy" at biology news

New binding target for oncogenic viral protein

...s. Clurman and Welcker suspect that by acting as a decoy and binding to Fbw7, T antigen protects cellular Fbw7 targets that facilitate viral replication and tumorigenesis. "I think this work underlines the importance of Fbw7 as an emerging tumor suppressor and the consequences of its loss in tumors," Dr. ...

UCLA scientists reveal how Nipah virus infects cells

...ith Nipah virus proteins embedded in its coat. The decoy virus successfully infected cells vulnerable to th...ect Nipah-resistant cells. In the final step, the decoy virus entered nerve cells and cells lining blood vessels by latching onto Ephrin-B2, proving that th...

Grabbing addiction by the tail

...te receptor and, once inside a neuron, serves as a decoy to prevent the loss of glutamate receptors. Yu Tian Wang, an HHMI international research scholar, and colleagues at the University of British Columbia in Vancouver report their findings in the November 25, 2005, issue of the journal Science. In a...

Tool developed to silence genes in specific tissues using RNAi

...nce, RNAi would do the job for them. Producing the decoy "small RNAs" that trigger RNAi has become a fairly simple process, Wilkinson says, but the difficulty has been to use these matches only in specific tissues, and to figure out a way to make this "treatment" last. The work by the M. D. Anderson team h...

Decoy pill saves brain cells

... The researchers injected laboratory mice with a decoy peptide containing a snippet of a receptor that fa...ped the toxic enzyme calpain would latch on to the decoy instead of the actual receptor, averting brain damage. As a test, the researchers then injected t...

Cancer-killing invention also harvests stem cells

...wo trigger cell death. The other three are called decoy receptors. Healthy cells contain a lot of decoy receptors, giving them a natural protection against TRAIL, whereas cancer cells mainly express the t...

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