New Technique for Tracking Gene Regulators
... protein known as CREB.“Though scientists have now decoded almost all of the entire humangenome ?the series of nucleotide bases (labeled A, T, G, and C) thatmake up the source code for running the machinery of the cell ?we arejust beginning to decipher it,?said biologist John Dunn, who ledBrookhaven’s role i...Researchers uncover sequence of major rice pathogen
...olve the problems rice blast presents. "That work decoded the string of letters that comprise the genome," Dean says. "This paper shows the work of the last two years in bringing this genome to life." Bringing the genome to life means capturing the biological meaning of the genome, Dean says. To do this, h......process by which the genetic information in DNA is decoded by the cell to manufacture proteins, the building blocks of life.) "It's difficult to experimentally observe how transcription factors bind to DNA at a distance from a gene, or how regulation happens," said Fidelis, a computational biologist in Live...Powerful new tool for studying brain development
...gs called probes bind to messenger RNA (mRNA)--the decoded form of the gene--and release a signal that can be seen using a special microscope. Gene expression refers to the production of mRNA, which becomes the blueprint the cell uses to make the protein coded for by that gene. The BGEM links these images w...Tool developed to silence genes in specific tissues using RNAi
... it was produced by DNA) as a single strand, to be decoded by ribosomes into the proteins that perform all the work of the cell. RNAi, therefore, recognizes the double strand of viral RNA as different, and sets in motion cell machinery that destroys the invading RNA. This involves cutting up the double-stran...Study finds how organs monitor themselves during early development
...ann and post-doctoral fellow Lilach Gilboa, Ph.D., decoded the process in the developing fruit fly ovary that allows the ovary to monitor the number of germ cells it contains and to correct that number if the need arises. Germ cells are cells that give rise to either sperm or egg and can ultimately give rise...Three-dimensional, miniature endoscope opens new diagnostic possibilities
... recorded, and the intensity of the various colors decoded by a spectrometer, which analyzes the wavelengths of light. Another device called an interferometer, which calculates structural information based on the interaction between two waves of light, provides the data required to create three-dimensional i...Common ancestry of bacterium and plants could be key to an effective new treatment for chlamydia
...eria is the result of genome sequencing, which has decoded the complete genetic blueprint for entire species. "This would not have been possible 10 years ago," said Leustek. "But now we have access to more that 500 different genomes in a data base. After having identified a gene in plants, I can quickly iden...Is there a pilot in the insect?
...that act as optic flow sensors. The team patiently decoded the functioning of these neurons using ultra-fine microelectrodes (with a diameter of a thousandth of a millimeter) and a specially designed microscope. They then produced an electronic microcircuit based on this principle. The most recent version we...Scientists sequence genome of parasite responsible for common sexually transmitted infection
Researchers have decoded the genetic makeup of the parasite that causes tri... the development of the parasite's metabolism. The decoded genome also revealed 800 genes for surface proteins that likely enable T. vaginalis to adhere to cel...