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Tag: "decade" at biology news

Mechanism identified for promising neurological drug

... The second observation, Swanson says, was made a decade ago by study co-author Tiina M. Kauppinen, PhD, currently a neurology research fellow at SFVAMC and UCSF, when she was a graduate student in Finland. Kauppinen found that minocycline, an antibiotic derived from tetracycline, prevents inflammation and...

Atmospheric ozone recovering in mid-latitudes, report shows

...bute the stabilization of ozone levels in the past decade in the 11- to 15-mile (18- to 25-kilometer) altitude region to the Montreal Protocol, enacted in 1987, and its amendments. The treaty phased out the use of ozone-depleting chemicals, including chlorofluorocarbons (CFCs) emitted from such sources as s...

Anti-inflammatory drug's potentially deadly side effect found to be rare

...till rare--we've seen about 50 cases over the last decade at Washington University School of Medicine." In patients with PML, the virus (named the JC virus for the first patient it was identified in) destroys the cells that make protective sheaths surrounding brain cells. Symptoms include vision loss, ment...

Thinner and younger

...insulin levels and body temperature. More than a decade ago several researchers, including John O. Holloszy, M.D., professor of medicine at Washington University, demonstrated that stringent and consistent caloric restriction increased the maximum lifespan in mice and rats by about 30 percent and protecte...

Landmark discovery of a Kaposi's sarcoma-associated herpesvirus receptor

...ause of his interest in how viruses enter cells. A decade ago, his research team was the first to identify CXCR4 as one of the coreceptors that allows HIV to gain entry into cells of the immune system. This discovery quickly led to the identification by Dr. Berger's group and several other research teams of...

Hopkins researchers discover genetic switch that turns off an oxygen-poor cell's combustion engine

...shyov and Gregg L. Semenza, who discovered HIF-1 a decade ago. ...

UMaine teams with fishermen to study affects of trawling on seafloor ecology

...ars, Watling estimates that it will take roughly a decade for the surface-dwelling organisms to reestablish themselves, but cautioned that a full recovery of the habitat would take much longer. "I am pretty firmly convinced that if the groundfishing industry doesn't soon begin to undertake measures to con...

Therapeutic prospects beyond Vioxx

...collaborated with FitzGerald at Penn over the last decade on this line of research. Funk is now the Canada Research Chair of Physiology at Queen's University, Ontario. "One does not need additional explanations to understand what we have seen in clinical trials. COX-2 inhibitors confer a small, but absolute...

The giant protein titin helps build muscles

.... The latest study, which arises from more than a decade of collaborative research by the Wilmanns and Gautel teams, gives a solution to how this might happen. Peijian Zou and Nikos Pinotsis from the Wilmanns lab obtained crystals of parts of the titin molecule bound to another protein, called telethonin. ...

Basic research leads to a novel cancer therapy

...opment of therapies against tumours. Also, over a decade ago, a team led by Ullrich discovered that by interrupting the oxygen and nutrient supply to tumour cells, it is possible to inhibit cancer development. The Max Planck scientists showed that tumour tissue just a few cubic millimetres in size can crea...

Flu not the only germ threat this time of year

...and children under 1 year of age. For more than a decade Falsey and Walsh, who are infectious disease experts at Rochester General Hospital, have been on the hunt for a vaccine against RSV. While they've identified several proteins on the surface of RSV, an important step toward creating a vaccine, none of...

U of MN researchers identify ataxia gene

...this historical and scientific journey more than a decade ago. She and her colleagues John Day, M.D., Ph.D., University of Minnesota, and Larry Schut, M.D., CentraCare Clinic in St. Cloud, Minn., examined and collected DNA samples from more than 300 Lincoln family members who live across the country, track...

For one Stanford doctor, the beat goes on during open-heart surgery

...o first used the procedure when it was developed a decade ago and now uses it only occasionally. "I don't have the time to devote to it. You need to do it often to be good at it." Which is exactly what Ihnken plans to do. He's completed more than 130 of the surgeries and does all his bypass work off-pump. ...

Boosting newborns' immune responses

... and rotavirus much less of a threat. For about a decade it's been known that people's first line of defense against infection is a group of receptors known as Toll-like receptors (TLRs) on the surface of certain white blood cells. Functioning like an early radar system, TLRs detect the presence of invadin...

UC Berkeley researchers create a biologically-inspired artificial compound eye

...chnology, a set of methods developed over the last decade to replicate nanoscale-sized structures. The material they chose for the artificial eyes was an epoxy resin that cures into a hardened form when exposed to ultraviolet light. They poured the resin into the dimpled molds, baked it at a low temperatur...

HIV accessory protein disables host immunity via receptor-protein intermediary

...bruary print issue of Nature Cell Biology. Over a decade ago, Penn's David Weiner, PhD, Associate Professor of Pathology and Laboratory Medicine, and colleagues reported that Vpr corrupted the glucocorticoid receptor (GR) pathway of the host cell. Vpr helps to usurp host-cell function by regulating cell di...

New book on rain forests, slash-and-burn agriculture

...out the developing world. It is based on the first decade of work by the Alternatives to Slash-and-Burn consortium, which was formed in 1992 by a group of concerned national and international researchers. Its authors include agronomists, foresters, economists, ecologists, soil scientists, anthropologists an...

NASA's AURA satellite peers into Earth's ozone hole

...it was colder than average. Only twice in the last decade has the ozone hole shrunk to the size it typically was in the late 1980s. Those years, 2002 and 2004, were the warmest of the period. Scientists also monitor how much ozone there is in the atmosphere from the ground to space. The thickness of the An...

New evidence supports century-old theory of cancer spread

...it continues to divide." Working for more than a decade with a diverse team of scientists at the Yale School of Medicine and other research centers, Pawelek concludes that there is now sufficient evidence for Aichel's proposal to be taken seriously by the research community. Pawelek's group began testing ...

UK sperm donor crisis

...ibly contributed to the 30% drop-out rate over the decade of the study, particularly in the early days when fertility issues were less well known to the public. The unit is also reviewing its high cut-off rate for semen quality. However, to achieve good freeze-thaw sperm quality and, hence, good success r...

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