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Tag: "debilitating" at biology news

Trying to control pain can be a double-edged sword, say scientists

...with persistent pain can cope with what is often a debilitating condition. Using fMRI scanners, which allow scientists to examine how the brain operates, the research, led by Dr Katja Wiech and Dr Raffael Kalisch, showed that when people feel that they can control their pain, an area of their prefrontal cortex a...

Hopkins scientists link immune response to 'ghost' parasites and severely congested sinuses

...ck the inflammatory chemical pathway but also have debilitating side effects, including loss of bone density, cataracts in the eye and weight gain. An estimated 32 million Americans suffer from persistent inflammation of the tissue that lines the nasal and sinus cavities, according to the United States Centers...

A new target for painkillers

...ils. "We found a new way to treat a chronic and debilitating form of pain suffered by hundreds of millions of people on Earth," says J. Michael McIntosh, a University of Utah research professor of biology, and research director and professor in the Department of Psychiatry. "It is a previously unrecognized mec...

Vaccine for brain tumors shows promising results

...d to leave healthy tissue unaffected and limit the debilitating side effects typically associated with traditional cancer treatments such as chemotherapy and radiation therapy. Vitespen has been granted fast track and orphan drug designations from the Food and Drug Administration in both metastatic melanoma (skin...

Therapeutic role found for carbon monoxide

...ulmonary arterial hypertension (PAH), an extremely debilitating condition that typically leads to right heart failure and eventual death. The new findings, made in an animal study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) and the University of Pittsburgh, are described in the September 2...

Buildup of damaged DNA in cells drives aging

... who was highly sensitive to the sun and had other debilitating symptoms including weight loss, muscle wasting, hearing loss, visual impairment, anemia, hypertension and kidney failure. The boy’s family had immigrated to Germany to seek better medical treatment for his condition. Extreme sensitivity to ultravi...

Humpback whales have brain cells also found in humans

... and are affected by Alzheimer's disease and other debilitating brain disorders such as autism and schizophrenia. Spindle neurons were also found in the same location in toothed whales with the largest brains, which suggests that they may be related to brain size. The authors note that spindle neurons probably...

Combination therapy shows promising results in patients with advanced lung cancer

...argets all fast growing cells and often results in debilitating side effects. Reckamp characterized the side effects seen with the combination therapy as minor. The next step is a larger Phase II study to confirm the efficacy of the combination therapy and further probe the mechanisms of Tarceva resistance, Reck...

'Cellular antennae' on algae give clues to how human cells receive signals

...netic defects in cilia can cause people to develop debilitating kidney disease or to be born with learning disabilities, extra fingers or toes, or the inability to smell. But no one really knows how cilia work, or, in some parts of the body, what their function is. "There are cilia all over within our brain, a...

New understanding of parasite cell structures may provide treatments for serious tropical diseases

...rible tropical disease called Leishmaniasis. This debilitating disease is found is more than 88 countries where a third of a billion people are at risk to contract it. In the same set of experiments, the researchers discovered a new pathway for protein movement in the trypanosome that may also be found in other...

Taking the wrinkles out of motoneuronal disease

...e activity. The diseases are severe and physically debilitating disorders which lead toprogressive weakness and wasting of muscles. Many of the diseases are incurable. Dr Meunier is developing botox to selectively deliver drugs to motoneurons to directly treatmotorneuron diseases. "I first became interested in ...

Viral hitchhiker inhibits Wolbachia bacteria's ability to proliferate

...lso enable the design of alternative therapies for debilitating illnesses such as river blindness and elephantiasis, whose pathologies are caused by Wolbachia bacteria living in the parasitic worms associated with these diseases. The new research, led by Seth Bordenstein, an Assistant Scientist in the MBL's...

Virus has 'catastrophic' affect on red squirrels, research shows

...nce programme clearly demonstrate the severity and debilitating nature of the squirrel poxvirus disease on red squirrels. "Given that the grey squirrel is an introduced species, and therefore the disease has occurred as a consequence of human action, the onus is very much on us to look for practical solutions...

Montreal researchers identify defects of immune cells

... susceptibility to candidiasis, a common and often debilitating infection in individuals infected with the human i...ungal infection due to candidiasis is one of these debilitating conditions," said Dr. Bhagirath Singh, Scientific Director of the Canadian Institutes of Health Rese...

Computational model simulates AZT metabolism in mitochondria

...ifferent hypotheses as to why AZT can lead to such debilitating side effects in some patients undergoing anti-retroviral treatment." ...

Device effective in zapping the pain out of migraines

... relief for millions of people who suffer from the debilitating disease. Results of a study found that the experimental device appears to be effective in eliminating the headache when administered during the onset of the migraine. The study, led by the Ohio State University Medical Center neurology investigat...

Brain enzyme treatment relieves memory lapse in Alzheimer's mice

...uld reverse lapses of memory characteristic of the debilitating disease. Treatments that elevate the protein, known as ubiquitin C-terminal hydrolase L1 (Uch-L1), might therefore have potential as a new therapy for Alzheimer's disease, according to the researchers. Currently available therapies have almost excl...

A Jekyll and Hyde of cytokines: IL-25 both promotes and limits inflammatory diseases

...lso limit the type of inflammation associated with debilitating diseases like inflammatory bowel disease, arthritis and multiple sclerosis, according to researchers from the University of Pennsylvania School of Veterinary Medicine. The researchers discovered how IL-25, a signaling protein known as a cytokine, bo...

New study reveals promising osteoporosis treatment

...lth. Osteoporosis is a silent, progressive, and debilitating disease characterized by bone loss and the thinning of cortical bone leading to bone fracture. In the United States, the disease affects an estimated 10 million older adults, resulting in more than 1.5 million fractures annually; the overwhelming maj...

Potential heart benefit found in stem cells

...personalized medicine and effective treatments for debilitating diseases drive progress in this area, moral and ethical dilemmas about embryonic cells continues to cloud the field. In research presented today at the American College of Cardiology's 55th Annual Scientific Session, scientists continue to explore m...

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