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Tag: "death" at biology news

Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer

...essiveunprotected sunbathing, can lead to cellular death ?recognized assunburn of the skin ?and may cause p...ducts(6-4PPs) ?contribute to the processes of cell death and cancerformation. Identifying the relative contributions of the two types ofdamage to tumor forma...

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...r time a result of the difference in the birth and death rates of the leukemia cells. Scientists have also since discovered that CLL is not a uniform disease but rather a disease that follows two distinct clinical courses in patients. Some patients require no treatment and have a lifespan of more than 20 ...

Computers to be used to find blueprint for new influenza drug

...n bed for a few days. But some outbreaks can cause death on a large scale ?the world-wide outbreak in 1918 killed more people than the First World War itself. We may now be facing another flu outbreak, this time originating from chickens in Asia. “If we are successful, we will have taken important steps i...

HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs

...conditions that make a person vulnerable to sudden death by a ventricular arrhythmia. There are several specific actions physicians can take to use this new information wisely, Drs. Ackerman and Badley say. The first is to screen by electrocardiogram for heart effects in vulnerable patients. The second is...

U of M researcher examines newly emerging deadly disease

...tivate large numbers of T cells), often leading to death due to hypertension and shock. Purpura fulminans has been identified in five cases in the Minneapolis-St. Paul, Minn., metropolitan area during 2000-2004, as described in the April 1, 2005 issue of Clinical Infectious Diseases. This new disease has a...

Enzyme allows B cells to resist death, leading to leukemia

...n theprogrammed signals that trigger normal B cell death (apoptosis). LivioTrentin and colleagues from Padu...ment of malignantcells with drugs that induce cell death decreased both Lyn expressionlevels and activity ?suggesting a direct correlation between high Lynac...

New imaging method gives early indication if brain cancer therapy is effective, U-M study shows

...atment. This indicates a different mixture of cell death pathways within the tumors. In the end, any change is good. When you think about it, if the treatment is not having an effect, the tumor will continue to grow without any change to water diffusion," Ross said. The researchers found that for each of ...

U-M scientists find genes that control growth of common skin cancer

...ed growing and wereeliminated by a programmed cell death process. These results areconsistent with previous work from other labs studying differentHh-associated tumors, “but we were very surprised to see that sometumor cells persisted after shutting down Gli2 expression,?saidDlugosz.In some of the regresse...

Critical role in programmed cell death identified

...al School geneticists have found links in the cell death machinery of worms and mammals, opening new avenue...m cells to self destruct. These results unify cell death models along the evolutionary spectrum, from simple animal systems to humans. In spite of its name,...

Probing The Promise And Perils Of Nanoparticles

...rticles damage cell membranes—enough to cause cell death in some cases—and how the damage can be prevented. "If you're inventing these sorts of materials, you need to be concerned about their impact," said Mark Banaszak Holl, a U-M professor of chemistry and of macromolecular science and engineering. "We'...

Papers of DNA Pioneer and Nobel Laureate Francis Crick Added to National Library of Medicine’s Profiles in Science Web Site

...e, editing his latest article just days before his death from colon cancer on July 28, 2004, at age 88. The online exhibition features correspondence, lecture notes, draft and published articles, laboratory notebooks, and photographs from the Francis Crick collection at the Wellcome Library. Visitors to t...

Gene Therapy For Parkinson's Disease Moves Forward In Animals

...blem.?/p> Parkinson's disease is caused by the death of brain cells that produce a vital chemical known...you get low-level expression, you can prevent cell death in a part of the brain called the substantia nigra. That's been shown before in rodent models, but i...

Potential Cure for Lymphoma in HIV patients

...T, lymphoma is still a majorcause of suffering and death in HIV-infected individuals. It’simportant to know that stem cell transplant is an available and highlysuccessful treatment option for these patients,?said Amrita Krishnan,M.D., a staff physician at the City of Hope Cancer Center and leadauthor of th...

The very unexpected life and death of a leukemic cell

...able to find any problems with the programmed cell death machinery in CLL cells. This was a hint that perha...attributed to the difference between the birth and death rates of the cells, according to the study. The researchers at the Institute for Medical Research a...

White blood cell waste disposal system plays critical regulatory role

...short lifespan and often die via a programmed cell death pathway called apoptosis within a matter of hours. Dying neutrophils are recognized and ingested by cells in the body tissues called phagocytes. Although the specific mechanisms that regulate the proper ratios of neutrophil production and destructio...

New RNA polymerase discovered in plants

...n plants to tumor development in humans to certain death in mice. Pikaard thinks that Pol IV helps make siRNAs that then direct DNA methylation to sequences matching the siRNAs. The results were published in Cell online, Feb. 10, 2005 and will appear in the March, 2005 print version of the journal. "Pol...

World's largest rainforest drying experiment completes first phase

...ing in full sunlight, begin to falter and die. The death of large trees ?trees that may take centuries to reach the top of the forest canopy and have trunks greater than 10 inches in diameter -- increased from about one percent per year before the rainfall exclusion began to nine percent in the fourth year...

Gene therapy for Parkinson's disease moves forward in animals

...he problem." Parkinson's disease is caused by the death of brain cells that produce a vital chemical known...you get low-level expression, you can prevent cell death in a part of the brain called the substantia nigra. That's been shown before in rodent models, but i...

Antibiotic might fight HIV-induced neurological problems

...ggers some of the same biological pathways of cell death and inflammation as these other diseases," says Sheila Barber, Ph.D., assistant professor of comparative medicine. "Testing minocycline in our animal model of HIV infection was really a logical next step." A multicenter clinical trial is being plann...

US life expectancy about to decline, researchers say

...hem will pay a very heavy price in terms of higher death rates and escalating health care costs." To estim... illustrate that in the coming decades the risk of death from obesity-related causes is about to rise. The hardest hit will be minorities, because of limited...

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