Dendritic cells offer new therapeutic target for drugs to treat MS and other autoimmune disease
... Center have found that a gene pathway linked to a deadly form of leukemia may provide a new way to treat autoimmune diseases, including multiple sclerosis. Their tests in cell cultures and mice suggest that blocking the pathway by interfering with a blood cell growth gene, known as FLT3, targets an immune ...Researcher says flu responders can learn from 1918 epidemic
...winter may bring with it one of the most sweeping, deadly outbreaks of killer flu that the world has ever seen. While that prospect would terrify the average person, it also intrigues Jim Higgins, a doctoral candidate at Lehigh University, who has been researching the 1918 flu pandemic that killed an estim...Emerging staph strains found to be increasingly deadly and deceptive
...own for the first time that these strains are more deadly and better at evading human immune defenses than more common S. aureus strains that originate in hospitals and other health-care settings. In a paper released today online in The Journal of Immunology, scientists from the National Institute of Aller...Once-dreaded leprosy 'replaced' by tuberculosis, say researchers
...salem and in London, that tuberculosis, a far more deadly disease, overtook leprosy, killing millions throughout Europe. Their conclusion is based upon the examination of DNA from human remains from the ancient and medieval periods in Israel and Europe. In these examinations, the scientists found traces of...CO2 sensing proves critical for fungal pathogens to adapt to life in air and human hosts
...t) from the air (low CO2) in the course of causing deadly fungal meningitis. The authors found that an enzyme called carbonic anhydrase (CA) plays a critical role in the yeast's growth in ambient air; the CA enzyme accomplishes this by providing bicarbonate substrates for fatty-acid biosynthesis and other c...HIV mortality in India drops with introduction of generic antiretroviral therapy
...ant additional step toward curbing the spread of a deadly disease in a resource-poor country. ...A new link between stem cells and tumors
...n stem cells before they divide, the result can be deadly tumors. Cells in the very early embryo are interchangeable and undergo rapid division. Soon, however, they begin differentiating into more specific types, finally becoming specialized cells like neurons, blood, or muscle. As they differentiate, the...New genetic test can detect clam disease
... be found in all coastal waters but doesn't become deadly to clams until it reaches a critical concentration in the water. Gast notes that although red tide got a lot of media attention this year, QPX is actually a bigger problem. The toxins that cause red tide in clams and other shellfish in New England d...Science's Breakthrough of the Year: Watching evolution in action
...instakingly reconstructed has a chilling coda: the deadly flu seems to have started out as purely a bird virus. Understanding the evolution of last century's deadly bird flu may help us predict and cope with the current bird flu threat. Other studies showed how sm...Plants have a double line of defence
...neighbouring plant tissue from infection. In this deadly line of defence, very different proteins play a key role ?particularly EDS1, PAD4 and SAG101. They were already known to researchers in other species of plants, which identify molecular traits only present in parasites by using immune receptors both ...Katrina floodwaters not as toxic to humans as previously thought, study says
...cal plants and refineries in the area, releasing a deadly brew containing toxic levels of benzene, hydrochloric acid and chlorine. Instead, high levels of bacteria and viruses were the biggest human threat, not exposure to chemicals, Pardue and his associates say. The researchers obtained 38 floodwater sam...Breaking the mold: Research teams sequence three fungus genomes
...ggers allergic reactions, asthma attacks--and even deadly infections among people with weakened immune systems. Now, in the December 22 issue of the journal Nature , scientists at The Institute for Genomic Research (TIGR) and their collaborators report the mold's sequenced genome. The genome could lead r......dy promising in the search for treatments for this deadly disease. First, shutting down the IKK2 signal had beneficial effects even when it was done a few hours after the stroke. That is important when thinking about possible human therapies; it usually takes time for a patient to reach the hospital. Second...Cord blood cells may widen treatment window for stroke
...iotechnology company developing cell therapies for deadly and debilitating disorders. Dr. Sanberg is a cofounder of Saneron CCEL, and Dr. Willing is a consultant. ...Tuberculosis still a risk for patients receiving HIV drugs
...ar," Dr. Girardi said. Since TB is a potentially deadly opportunistic infection for patients with HIV, doctors need to be aware of the risk and take certain precautionary measures. "HIV-infected patients, even when treated with HAART, remain at increased risk of developing tuberculosis," Dr. Girardi said.......rist could probably order the building blocks of a deadly biological weapon online, and receive them by post...ch as smallpox, and using them to engineer new and deadly pathogens. Customers typically submit sequences by email or via a form available on a company's web...UCLA discovery will aid in treatment of patients with a deadly brain cancer
...cer have identified key characteristics in certain deadly brain tumors that make them 51 times more likely to respond to a specific class of drugs than tumors in which the molecular signature is absent. The discovery of the telltale molecular signature ?the expression of a mutant protein and the presence o...Asleep in the deep: Model helps assess ocean-injection strategy for combating greenhouse effect
...d, "because carbon dioxide is known to have driven deadly water eruptions." In 1986, a CO2-driven eruption in Cameroon's Lake Nyos killed some 1,700 people, as well as animals in the area; two years earlier, a smaller release of CO2 from Lake Monoun in the same country resulted in 37 human deaths. The death...Researchers develop new method to help find deadly malaria parasite's Achilles heel
The most deadly malaria parasite has protein 'wiring' that differs markedly from the cellular circuitry of other higher organisms, a finding which could lead to the development of antimalarial drugs that exploit that difference. Researchers at UCSD have discovered t...'Good' bacteria could save patients from infection infection by deadlier ones
...British public hospitals, especially involving the deadly MRSA (methacillin resistant staphylococcus aureus) bacteria. Despite being around for 40 years, these bacteria are still basically found only in hospitals. The question Spigelman asks is why? Spigelman, who is also a visiting professor at Universit...