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Tag: "deadly" at biology news

Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma

... the patients of Ewing's sarcoma, a rare and often deadly bone cancer that generally strikes young adults. Despite aggressive therapy, about 40 percent of patients with Ewing's family tumors and 95 percent with metastases die as a result of their disease. Scientists now recognize that Ewing's sarcoma resul...

Disease progression model of pancreatic cancer developed by Penn researchers

...this, they hope to develop new treatments for this deadly disease. Advanced pancreatic cancer is among the most lethal of cancers, with a one-year survival rate after chemotherapy of only 17 to 28 percent of patients, according to the National Cancer Institute. Sunil R. Hingorani, MD, PhD, and David A. Tuv...

Retrovirus struck ancestors of chimpanzees and gorillas millions of years ago, but did not affect ancestral humans

...s of chimpanzees and gorillas were infected with a deadly retrovirus about three to four million years ago, but there is no evidence it infected ancestors of modern-day humans, according to research by genome scientists. The virus struck after humans had split off the evolutionary tree from primates, resear...

Venom doc tracks down snake bioweapons

...s something peculiarly fascinating in the use of a deadly toxin as a life-saving medicine," Fry says. "The natural pharmacology that exists within animal venoms is a tremendous resource waiting to be tapped." By comparing the amino acid sequence of each toxin to the amino acid sequences of multiple protein...

Researchers test new therapy for advanced melanoma

Melanoma is a particularly deadly form of skin cancer very resistant to treatment. Researchers at H. Lee Moffitt Cancer Center & Research Institute and the University of South Florida are testing a promising new therapy that prompts the immune system to aid in the fight against m...

Newly discovered protein an important tool for sleeping sickness research

...es of sub-Saharan Africa are threatened daily by a deadly parasitic disease known as African sleeping sickness. The disease is caused by organisms called trypanosomes, which are spread by the tsetse fly. African sleeping sickness affects approximately 500,000 people in sub-Saharan Africa, a quarter of whom ...

Breakthrough System for Understanding Ocean Plant Life Announced

...es of sub-Saharan Africa are threatened daily by a deadly parasitic disease known as African sleeping sickness. The disease is caused by organisms called trypanosomes, which are spread by the tsetse fly. African sleeping sickness affects approximately 500,000 people in sub-Saharan Africa, a quarter of whom ...

Active Vaccine Prevents Mice From Developing Prion Disease

...curring naturally in the body. But the prions turn deadly by changing shape. These "misfolded" proteins tend to aggregate in toxic, cell-killing clumps. As an infection takes hold, prion proteins invade brain tissue and force normal proteins to adopt their configuration. In time, the diseased animal develop...

New vaccine means bye-bye to bacteria in the lung

...oduction and protected the mice from exposure to a deadly dose of the bacteria. Importantly, the mice could be repeatedly given the vaccine and the immune response against P. aeruginosa was boosted. Usually, adenovirus vectors do not allow for repeated infection. These results may be useful in the developm...

High fidelity keeps human DNA assembly line humming

...alled the DNA conveyer belt. They did this using a deadly mushroom toxin, alpha-amanitin. Alpha-amanitin is...the poison of the death cap mushroom, which can be deadly to humans. In 54 A.D., Emperor Tiberius Claudius was fed a death cap mushroom by his wife Agrippina ...

New understanding of cell movement may yield ways to brake cancer's spread

...organisms, and cancer cells metastasize, spreading deadly disease through the body. Scientists studying these migrations didn't know how cells determined where to go. Until now. A Burnham Institute study has identified a fragment of a protein that senses chemicals that induce a cell to move into the right ...

Discovery could be key to bioterrorism defense

...made a major breakthrough in efforts to combat two deadly viruses that could be engineered for use as bioweapons. The team isolated the functional receptor for the Nipah and Hendra viruses--naturally occurring and highly pathogenic paramyxoviruses for which no treatments or vaccines are currently available....

Immune system's distress signal tells bacteria when to strike back

...form them from benign passengers in the bowel into deadly blood-stream invaders. "Most of the time these microbes are content to live and grow in our intestines," said John Alverdy, M.D., professor of surgery at the University of Chicago and director of the study. "They don't feel the need or even look for...

Researchers develop promising new gene network analysis method

...ty in Israel ?set out to answer a question. When a deadly "oncoprotein" is switched on, what chain reaction of gene activity does it set off? The protein, c-Myc, causes cells to multiply. If the protein is produced unchecked, it can cause breast, colon and other types of cancer. C-Myc contributes to more t...

Insects develop resistance to engineered crops

...as maize and cotton, creates these toxins that are deadly to insects but harmless to humans. Bt crops were first commercialized in 1996, and scientists, critics and others have been concerned that widespread use of Bt crops would create conditions for insects to evolve and develop resistance to the toxins....

Compound might defeat African sleeping sickness, clinical trial beginning this month

...lyn and he did in Africa inspired Olson to work on deadly but neglected illnesses, she said. "What goes 'round, comes 'round," Olson said. "We have a real opportunity with DB289 and other drug candidates in the pipeline to help solve some very difficult health problems affecting millions of people in devel...

Stem Cells Found In Cerebellum; Possible Cell of Origin for Childhood Brain Tumors

...em cells in the cerebellum, a brain region where a deadly type of brain tumor originates. Their findings suggest that such tumors, called medulloblastomas, could arise from stem cells gone awry. The cerebellum is the brain's control center for motor coordination and cognitive function, yet little has been ...

Engineered skin offers clues to melanoma development

When it comes to the deadly skin cancer melanoma, studying functional tissue rather than cell lines may better provide insight into the disease's development, according to new research from a Howard Hughes Medical Institute predoctoral fellow at Stanford University School of Me...

Ibruprofen and other commonly used painkillers for treating inflammation may increase the risk of heart attack

When it comes to the deadly skin cancer melanoma, studying functional tissue rather than cell lines may better provide insight into the disease's development, according to new research from a Howard Hughes Medical Institute predoctoral fellow at Stanford University School of Me...

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

When it comes to the deadly skin cancer melanoma, studying functional tissue rather than cell lines may better provide insight into the disease's development, according to new research from a Howard Hughes Medical Institute predoctoral fellow at Stanford University School of Me...

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