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Tag: "deadliest" at biology news

Catching cancer's spread by watching hemoglobin

...helping to diagnose diseases such as melanoma, the deadliest form of skin cancer. The technique can image blood vessels up to a millimeter below the surface. Looking at blood vessels just below skin growths would be very useful for distinguishing between malignant and benign skin tumors, and would remove the c...

RNA splicing factor implicated in ovarian tumor cell growth

...o die from the disease. "Ovarian cancer is the deadliest disease among all gynecological cancers," said He. "Two factors account for the dismal mortality outcomes. One is the absence of reliable early detection markers, and the other is inadequacy of present therapy for advanced disease. To improve patient...

A genetic 'gang of 4' drives spread of breast cancer

...umor break off and invade another organ. It is the deadliest transformation that a cancer can undergo, and therefore researchers have been looking for specific genes that propel metastasis. In the newly published experiments, the researchers also found that they could reduce the growth and spread of human b...

New study may show how to forestall a fatal, virus-caused immune-system meltdown

...s recovery. But in the case of some of the world’s deadliest pathogens ?including the Ebola, Marburg and Lassa fever viruses, as well as the influenza virus strain responsible for the 1918 flu pandemic ?the immune system itself actually becomes the most dangerous element of the disease. All too often, a sudden...

HIV protein enlisted to help kill cancer cells

...ms could provide new options for patients with the deadliest cancers ?such as pancreatic cancer ?which have very low rates of survival. He says he believes that clinical trials of these compounds could be just a few years away. Hawkins began researching TAT-Bim after discussions with co-author Richard S. Hot...

Researchers discover surprising drug that blocks malaria

...in PLoS Medicine. Malaria, one of the top three deadliest diseases in the developing world, is resurging worldwide because of drug resistance and the lack of an effective vaccine, Haldar said. Jamaica recently reported an outbreak of malaria after it had been eradicated in that country for 50 years. A b...

A fisheye view of the deadliest breast cancer

Inflammatory breast cancer (IBC) is the deadliest form of the disease, with fewer than half of those diagnosed today having a five-year prognosis for survival. To find out what drives this most aggressive of human breast cancers, and to rapidly screen for drugs that might stop IBC, researchers at ...

Experimental vaccine protects mice against deadly 1918 flu virus

... create a vaccine that protects against one of the deadliest forms of influenza the world has ever seen?" adds Dr. Nabel. "It's because the 1918 flu virus has been reconstructed that we are now able the further understand it. Hopefully, this virus will help us to develop effective vaccine strategies for curren...

New potential drug target in tuberculosis

Tuberculosis remains one of the deadliest threats to public health. Every year two million people die of the disease, which is caused by the microorganism Mycobacterium tuberculosis. Roughly one third of the world's population is infected and more and more bacterial strains have developed r...

Malignant melanoma cells secrete protein required for embryo formation

...odulation of tumor cells. Melanoma is one of the deadliest forms of cancer. The five-year survival rate for melanoma patients with widespread disease is between 7 percent and 19 percent. ...

Taipan venom no snake oil

...nces who studied the venom of eight of Australia's deadliest land snakes for their therapeutic potential. His study focussed on the genes in the coastal taipan's venom that are responsible for the pro coagulant or blood clotting agent called Factor X which could stem blood flow in a matter of seconds. A drug...

Scientists develop malaria forecasting tool to predict disease risk

...ling the disease. Malaria is one of the world's deadliest diseases, killing more than one million people every year, as well as infecting a further 500 million worldwide. The mosquito-borne illness is endemic in several regions globally, but is most acute in Africa, home to an estimated 90 per cent of all ...

Plant-derived vaccines safeguard against deadly plague

...ts into vaccine production factories to combat the deadliest form of plague. The vaccine elicits a protective immune response in guinea pigs. The results are considered to be a milestone in the future development of a new vaccine for human use. Plague, caused by a rod-shaped bacterium called Yersinia pestis, ...

New cellular flaw found in some virulent breast cancers

...een in about 10 percent of breast cancers ?and the deadliest ones. The cancer results from a cascade of molecular events. The overproduction of a common protein, cyclin D1, hyperstimulates a growth switch, CDK4 kinase, causing it to unleash a virulent proliferation of cancer cells and creating a tumor with a ...

US/African project deciphers deadly parasite genome

...irst author of the 2002 paper on the genome of the deadliest human malaria parasite, says that several of the malaria parasite's metabolic pathways that Theileria lacks are found in an intracellular structure called the apicoplast. "This information could be used to develop drugs that could be targeted specifi...

Forsyth scientists find three bacteria associated with oral cancer

...of oral squamous cell carcinoma (OSCC)--one of the deadliest of cancers because it often goes undetected in its...stages live for five years¡Xplacing OSCC among the deadliest of cancers. "Far too many people are not diagnosed until their oral cancer is in its advanced stage...

Newfound roadblock to interferon effectiveness against malignant melanoma

... established therapies. Malignant melanoma is the deadliest form of skin cancer, and if not treated successfully, it can spread to affect the liver, lungs, or brain. Chemotherapy fights the disease with limited efficiency, and the use of interferon has become the most established immunotherapy for advanced-st...

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

...d in the development of melanoma. Melanoma is the deadliest form of skin cancer, resulting from the malignant transformation of cells called melanocytes. Over the past four decades, the incidence of melanoma has risen 15-fold, a more rapid increase than that of any other cancer. "The only current treatment i...

Ibruprofen and other commonly used painkillers for treating inflammation may increase the risk of heart attack

...d in the development of melanoma. Melanoma is the deadliest form of skin cancer, resulting from the malignant transformation of cells called melanocytes. Over the past four decades, the incidence of melanoma has risen 15-fold, a more rapid increase than that of any other cancer. "The only current treatment i...

Engineered skin offers clues to melanoma development

...d in the development of melanoma. Melanoma is the deadliest form of skin cancer, resulting from the malignant transformation of cells called melanocytes. Over the past four decades, the incidence of melanoma has risen 15-fold, a more rapid increase than that of any other cancer. "The only current treatment i...

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