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Chemists create 'Superbowl' molecule; May lead to better health

In a development that could one day score a touchdown for better health, chemists in Australia have created a "superbowl" molecule that shows promise for precision drug delivery, according to a recent study in the Journal of the American Chemical Society. Shaped like a miniature footba...

Wisconsin scientists grow critical nerve cells

...lling of an eyeball. The new development could one day help victims of spinal-cord injuries, or pave the ... and provide access to critical cells that may one day be used in therapy, it will likely be many years before they can be tested in humans, Zhang says. ...

Molecular biology fills gaps in knowledge of bat evolution

... bats from the tropics, that fly mostly during the day - known to biologists as megabats - emerged from four major lineages of smaller and more widely dispersed, mostly insect-eating, night-flying bats, known as microbats. These microbats - also known for their highly specialized echolocation - originate...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

...any way, they mated females with males, dating the day of their pregnancy, which lasts three weeks. They separated the mothers into two groups. The control group ate as much chow as they wanted during the entire pregnancy. The other group also was fully nourished during the first two weeks but undernouri...

Clam embryo study shows pollutant mixture adversely affects nerve cell development

...uman nerve cell development--knowledgethat may one day provide clues about such neurological mysteries asautism spectrum disorder or attention deficit hyperactivity disorder. Totest her hypothesis, MBL scientist Carol Reinisch and her colleaguestreated developing surf clam embryos (Spisula solidissima) ...

Study identifies predictors of HIV drug resistance in patients beginning triple therapy

...uman nerve cell development--knowledgethat may one day provide clues about such neurological mysteries asautism spectrum disorder or attention deficit hyperactivity disorder. Totest her hypothesis, MBL scientist Carol Reinisch and her colleaguestreated developing surf clam embryos (Spisula solidissima) ...

Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease

...d various proteins that interact with them may one day be useful for understanding, diagnosing, and even developing new treatments for some cancers." ...

Nano-Probes Allow an Inside Look at Cell Nuclei

... applied it to a problem faced by biologists every day ?getting inside the nucleus, a desirable target because the cell's genetic information resides there," says Chen. First, they had to breach the nuclear membrane, which has pores that are only about 20 nanometers wide. To fit through these tiny slits...

International trial of two microbicides begins

...t sexually transmitted infections (STIs)--will one day be a key tool in the fight against HIV/AIDS. Women make up nearly half of all people living with HIV worldwide. "The majority of new cases of HIV infection in women result from heterosexual intercourse, but women may not always be able to insist tha...

MetaChip provides quick, efficient toxicity screening of potential drugs

...t sexually transmitted infections (STIs)--will one day be a key tool in the fight against HIV/AIDS. Women make up nearly half of all people living with HIV worldwide. "The majority of new cases of HIV infection in women result from heterosexual intercourse, but women may not always be able to insist tha...

The very unexpected life and death of a leukemic cell

...viduals with CLL a small dose of heavy water every day for 84 days, and the tagged water was incorporated into the DNA of the leukemia cells. This provided the researchers a way to track the cell division, or "birth" of new leukemia cells. Chiorazzi and his team calculated birth and death rates of the le...

NJIT Presidential Award winner takes stem cell research another step

...such as combining allograft with stem cells." One day soon, as a result of Arinzeh's research, patients could be treated with off-the-shelf stem-cell therapies instead of drugs. In five years, say, a patient with a bone ailment would visit a doctor and be injected with a ready supply of stem cells. The ...

TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas

...ck TEL2 activity, since such an approach might one day represent an effective treatment for leukemia patients." Other authors of the report include Ayten Kandilci, Cintia Carella, Jonas A. Nilsson, Jennifer A. Brennan, Kelli Boyd, John Cleveland (St. Jude); and Sema Sirma and Ugur Ozbek (Istanbul Univer...

Unexpressed But Indispensable -- The DNA Sequences That Control Development

...ith a green fluorescent protein (GFP) reporter. By day two of development, 23 out of 25 CNEs injected had upregulated GFP expression, indicating interaction of these sequences with endogenous transcription factors. Different CNEs caused different regional patterns of expression, in keeping with their pre...

Measuring the impact of post-genomics on Mediterranean populations

...enomics and Integrative Biology (IGIB), kicked off day one (4 March) with his keynote address called ‘Pre...health research in the post-genomic era? Later on day one, Ayoade Oduola of the World Health Organisation, asked “How can we tackle the ‘genomic divide?be...

Ophthalmologists Use Artificial Silicon Retina Microchip To Treat Vision Loss

...Rush faculty. Patients leave the hospital the same day and will be followed for two years as part of the study, and then indefinitely. The patients were recruited from a pool of about 5,000 applicants. The implants are designed for people with retinal diseases such as macular degeneration and retinitis...

Chemists identify key gene in development of type 1 diabetes

...ciates hope that the experimental compound can one day be developed into a long-acting oral drug that could be taken by prediabetic people to achieve lasting protection, perhaps a lifetime. But such a drug would take years to develop and test, the researchers caution. Likewise, effective gene therapy aga...

Towards precise classification of cancers based on robust gene functional expression profiles

...ciates hope that the experimental compound can one day be developed into a long-acting oral drug that could be taken by prediabetic people to achieve lasting protection, perhaps a lifetime. But such a drug would take years to develop and test, the researchers caution. Likewise, effective gene therapy aga...

Children's taste sensitivity and food choices influenced by taste gene

...PROP solution. "This type of information will one day help to improve the diets of our children by allowing us to devise better strategies to enhance fruit and vegetable acceptance in children who are sensitive to bitter taste," comments Mennella. "It may be that childhood represents a time of heightene...

Ophthalmologists implant five patients with artificial silicon retina microchip

...Rush faculty. Patients leave the hospital the same day and will be followed for two years as part of the study, and then indefinitely. The patients were recruited from a pool of about 5,000 applicants. The implants are designed for people with retinal diseases such as macular degeneration and retinitis...

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