Unique dual target specificity of kinase inhibitor key for success against cancer
...l cancer therapeutics that have been discovered to date as it exhibits a broad action without harmful side effects." ...Researcher studies, treats military with 'silent disease'
... we've asked for deployment delays," she said. "To date they have not denied us once." According to a 1999 Defense Department report to Congress, military personnel today are at a lower risk of hepatitis C infection because of the screening that's done before they enter the military and while they're se...Joslin discovers signs of residual islet cell function in people with long-term type 1 diabetes
...n-dependent continuously for at least 25 years. To date there have been approximately 2,400 50-Year Medals awarded and 17 distinctive 75-Year Medals. The Medalist Study began in April 2005 to identify physiological, clinical, genetic and other factors shared by the Medalists. The study being presented a...Study identifies substances in grapefruit juice that interact dangerously with some drugs
...the likely culprit. "This is the best evidence to date that furanocoumarins are the active ingredients in grapefruit juice that cause the interaction with medications," said Dr. Paul Watkins, the Dr. Verne S. Caviness distinguished professor of medicine and director of UNC's General Clinical Research Cen...Hair samples show babies can be exposed to 'crystal meth' while in the womb
...n a fetus are not fully known, but the evidence to date points to restricted fetal growth and developmental problems. Crystal meth users were also significantly more likely to use other drugs, the results showed. Most (85%) of the 396 samples positive for crystal meth also tested positive for at least...Tests for 'face-blindness' reveal disorder may not be so rare
...ctures of other objects. Reports of prosopagnosia date back to antiquity, although it wasn't until 1947 that researchers made the first modern, extensive description of symptoms. The neurological basis of the disorder remains poorly understood, although research has confirmed that the brain processes fac...Study shows interruption of antiretroviral therapy increases risk of disease and death
... the largest HIV/AIDS therapy studies conducted to date show that a specific strategy of interrupting antiretroviral therapy more than doubles the risk of AIDS or death from any cause. Researchers affiliated with the Mailman School of Public Health and Harlem Hospital Hospital led a large multi-center int...High HPV concentrations combined with smoking significantly raise risks of cervical cancer
...cancer-free women in one of the largest studies to date to examine the relationships between smoking and the human papilloma virus (HPV). The virus and smoking behavior have long been associated with the disease, but not enough evidence has come forth to determine how either may cause the disease. Gunn...The first tree genome is published: Poplar holds promise as renewable bioenergy resource
...ic sequencing facility and only the third plant to date to have its genome completely sequenced and published. The first, back in 2000, was the tiny weed, Arabidopsis thaliana, an important model for plant genetics. Rice was the second, two years ago. Populus trichocarpa is one of the tallest broadleaf ha...Engineer ramps up protein production, develops versatile viral spheres
...class of materials," Swartz says. "For example, to date we've been seriously limited in our ability to both produce and to modify capsids to turn them into effective vaccines." But now researchers in Swartz's lab, principally doctoral students Brad Bundy, supported by a Stanford Graduate Fellowship, and...Genetic study of Neanderthal DNA reveals early split between humans and Neanderthals
In the most thorough study to date of the Neanderthal genome, scientists suggest an early human-Neanderthal split. The two species have a common ancestry, say the authors, but do not share much else after evolving their separate ways. The study, published in this week's issue of Scien...Pattern of human Ebola outbreaks linked to wildlife and climate
...ade-long study, published this month (with a cover date of January) in the journal Transactions of the Royal Society of Tropical Medicine and Hygiene, tracked animal disease outbreaks and human exposure to the Ebola virus in Gabon and adjoining northwestern Republic of the Congo (RoC). The researchers fo...Air travel and flu: Post-9/11 restrictions delayed start of season
... the epidemic to spread across the country and the date of the national peak in flu deaths. They used gove...US was about two weeks, and that the national peak date was within two days of the average date ?February 17. Flu spread more slowly in years when the numbe...Ancient ape ruled out of man's ancestral line
...ates. The team used uranium lead chronology to date the remains. Working on extracts of stalagmite deposits from immediately above and below the body, they dated the skeleton at around 2.2 million years old. Their findings, published in the American journal Science, are controversial. Earlier estim...Two studies on bee evolution reveal surprises
...g the largest molecular and morphological study to date on bee family-level phylogeny -- the evolutionary development and diversification of a species. Their goal was to examine the early evolutionary pattern of bees and how their evolution relates to the evolution of flowering plants. Flowering plants ar...Firefighters face increased risk for certain cancers
...UC-led study is the largest comprehensive study to date investigating cancer risk associated with working as a firefighter. "We believe there's a direct correlation between the chemical exposures firefighters experience on the job and their increased risk for cancer," says LeMasters, professor of epide...New technology to speed up research into Huntington's disease
...ciated with these traditional methods, progress to date in trialling new treatments for cognitive deficits has been slow with contract research organisations understandably reluctant to engage with such research. Given the ease of use of the touch screen system, it is hoped this will change. Dr Jenny M...A valuable fly for research into disease
.... The role of the fly Studies using Drosophila date back to the last century and have provided valuable insight into the fundamental principles of biology and genetics. Only in recent years, however, and thanks in large part to the discovery of the high degree of homology between the genetic make-up o...'Protecting virus' offers instant flu protection and converts flu infections into their own vaccines
... same method to enter the cell. Laboratory work to date has used a drop of saline containing the protecting virus, squirted up the nose. Aerosol administration, used already for some vaccines, would be another way and is more user-friendly than injections. The protecting virus could also be a useful tr......y was unexpected because the literature written to date does not contemplate the presence of this type of protein in the chloroplast. Once the presence of this type of protein in the chloroplast was ascertained, the scientists asked themselves if it were the cell organ itself that was glycosylating. Th...