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Tag: "database" at biology news

Primitive yeast yields secrets of human cholesterol and drug metabolism

...mans by looking for similar proteins in a computer database and repeated their experiments in human kidney cells engineered to lack the human version of Dap1. As in yeast, the altered human cells accumulated cholesterol precursors and died because cholesterol is essential for cell survival. To show that Da...

Scientists perform 'tricky' operation

...rch (TIGR) and subsequent annotation of the genome database has opened many avenues of research by providing a searchable data set," Ms Dunne said. "Drug resistance in many human pathogens is increasing. T. vaginalis is among these, with no alternative drugs approved to treat resistant infections. "This...

Elderly spinal cord injuries increase five-fold in 30 years, Jefferson neurosurgeons find

... higher rates of mortality. Researchers reviewed a database of 3,481 consecutive acute penetrating and blunt spinal cord and spine-injured patients treated at Jefferson Regional Spinal Cord Injury Center over a 28-year period (1978-2006). Overall annual admissions for SCI at Jefferson's Spinal Cord Inju...

New study may show how to forestall a fatal, virus-caused immune-system meltdown

...tein-scanning chip and a uniquely capable computer database to examine the activation and deactivation of more...sis?program, which draws on a large-scale computer database of biochemical interactions that have been described in a wide variety of peer-reviewed scientific p...

Protein fragments sequenced in 68 million-year-old Tyrannosaurus rex

...es out of a mass spectrometer, it is compared to a database of existing amino acid sequences. Collagen is a hi...ested mastodon bone, sent by Schweitzer, against a database of existing amino acid sequences and against a set of mastodon theoretical sequences. He identified ...

Fighting influenza & co. with 40,000 blood samples

...g the partners. The Hamann Company is developing a database solution to acquire the medical data and analyse the results, which are extensive. In this manner, current respiratory diseases in the EU are to be recorded in coming years using a standardised format. New immune tests which are being developed by th...

Study calculates patient time costs associated with cancer care

...rveillance, Epidemiology, and End Results–Medicare database on more than 760,000 patients with 11 different types of cancer and from 1.1 million Medicare enrollees without cancer. Using data from 1995 to 2001, they estimated each patient's time spent at physician and emergency room visits, chemotherapy treatm...

LIAI completes world's most comprehensive analysis on influenza virus data

...study, using information from a worldwide research database funded by the National Institute of Allergy and In...ublic last summer. LIAI researchers developed the database ?which is the world's largest repository of scientific data on how the body's immune system responds...

New details on how the immune system recognizes influenza

Drawing upon a massive database established with funds from the National Institute...iers on dozens of pathogens. "The purpose of the database is to provide a catalog of molecules and structures that scientists around the world can quickly acc...

Gene found for rare disorder may reveal new pathway in mental retardation

... and Jackson together maintain the world's largest database of patients with CdLS. The current study screened 115 patients who did not have mutations in the NIPBL gene, but who were judged to have CdLS or a milder variant of the disease, based on evaluations by clinical geneticists. Of the 115 patients, 1...

Study of protein folds offers insight into metabolic evolution

... and proteomic information: the metabolic pathways database of the Kyoto Encyclopedia of Genes and Genomes, and the Structural Classification of Proteins database. They combined these two data sets with phylogenetic reconstructions, or family trees, of protein fold architectures in metabolism. They created a ...

Scientists seek useful traits in wild cottons

...k scientists enter this information into a genetic database which they share with other scientists and the public. This database will complement the Texas A&M University System's cotton breeding program, Gannaway said. An ove...

Study identifies 5 genetic themes key to keeping stem cells in a primitive, flexible state

...om StemBase, the largest stem cell gene expression database in the world. Designed by bioinformaticist Dr. Miguel Andrade, the database includes data from thousands of DNA microarrays submitted mainly by scientists in Canada’s Stem Cell...

Breakthrough developments in rheumatoid arthritis reported

...en and his colleagues have been amassing a genetic database complete with siblings with rheumatoid arthritis (...sting technology, Illumina, Inc. will maintain the database and make it available to scientists. The data will not include personal identifiers but scientists ...

New study finds genetically engineered crops could play a role in sustainable agriculture

...y. The study is accompanied by a searchable global database for agricultural and environmental scientists studying the effects of genetically engineered crops. Biotechnology and genetic engineering are controversial because of concerns about risks to human health and biodiversity, but few analyses exist that...

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