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Tag: "database" at biology news

DNA conclusive yet still controversial, Carnegie Mellon professor says

...it" technique, in which investigators search a DNA database to find a match of DNA found at a crime scene and then collect other evidence to build their case -- as opposed to first identifying a suspect through other evidence and then using DNA to confirm their case. Some critics claimed that this practice co...

Discovery of new molecular tools for biosynthesis could lead to advances in use of pectin

...protein it encodes while searching the genetic map database for a common laboratory plant in the mustard family, Arabidopsis thaliana. The identification of GAUT1 as a galacturonosyltransferase that synthesizes pectin, a family of complex polysaccharides present in the cell walls of all land plants, means t...

Ticks, flukes, and genomics: Emerging pathogens revealed

...tics? For the first time, our comparative genomics database offers a resource for tackling these questions." ...the new work as well, by accessing the comparative database now online at http://www.tigr.org/sybil/rcd/ . This genome sequencing project work was funded by th...

Study in Science holds promise for a new approach to drug therapy

... to see which drug-like molecules from an existing database of 1990 known structures would bind tightly to the hotspot, and to rank them. In general,tight binding suggests that a drug candidate has the potential to remain bound to its target long enough to have the desired effect. Of the compounds found throu...

UC San Diego partners with Venter Institute to build marine microbial genomics cyberinfrastructure

...l Institutes of Health's GenBank. The metagenomics database will include new sequences, genes and gene familie...ocal laboratory PC clusters directly to the CAMERA database and tools using the National LambdaRail or international optical circuits, resulting in up to a hund...

Study: Competition for sex is a 'jungle out there'

...ly. Vamosi, Knight and their colleagues created a database of more than 1,000 pollination experiments conducted worldwide. "If pollinators are doing a good job, you wouldn't expect a treatment effect," Knight said. "But for some of our plants we saw a huge treatment effect. We saw that a lot of the plants...

HortResearch science reveals the natural potential of apples

...d sustainably produced." Dr Ferguson said the EST database has already helped expand scientific understanding...n apple colour expression. "Further work with the database will undoubtedly yield even more exciting advances in the future." Releasing the ESTs into the publ...

Less is more, gene study shows

...d thing." Zhang's group started by scrutinizing a database of human pseudogenes---stretches of DNA that look ...o 80. Next, Zhang and his team consulted another database called Gene Ontology, which lists the functions of all genes for which such information is known. Th...

Oh, rats! Designer animals reveal possible heart disease genes

...e hypertension, among other conditions. The online database resulting from the study, dubbed TREX, is available free of charge at: http://pga.tigr.org/ . TIGR continues to study the panels of designer rat strains, and Lee hopes in the future to knock out specific candidate heart disease genes, directly test...

Stanford/Packard scientist's data-mining technique strikes genetic gold

...of thousands of microarray experiments in a single database based on the terms, or concepts, used by the submitter to describe the experiment. They then looked for findings shared by several experiments with similar concepts, such as tissue type, for example. Comparing results from many similar experiments al...

'Genetic network' guards against lethal DNA damage

...al DNA damage is a first step in the creation of a database of disease-causing combinations of mutated human genes, according to researchers at The Johns Hopkins University School of Medicine led by Jef. D. Boeke, Ph.D. In a report in the March 10 issue of Cell, the Hopkins team described a genetic network th...

Virginia Bioinformatics Institutes launches microbial database

... Tech have launched a publicly-available microbial database to host a range of microbial genome sequences. Th...sojae and Phytophthora ramorum. The purpose of the database is to make the recently completed genome sequences of these pathogens as well as powerful analytical...

Efficiency, not more doctors, is the prescription for aging population

...ademic medical centers. Using the Medicare claims database to examine the experience of chronically-ill people who received most of their medical care at academic medical centers, the researchers calculated the physician workforce inputs per patient during their last 6 months of life. Their analysis found ...

New method for identifying microbes

...s, this "ribotyping" technique makes use of a vast database for comparison. "If there's still no match," said van der Lelie, "then the tag probably identifies a brand new species, which is also very interesting!" In another test with possible applications for identifying agents used in bioterror attacks, th...

Anti-inflammatory drug's potentially deadly side effect found to be rare

... patients and either sent the results to a central database if they suggested little chance of PML or, if indications of potential PML were detected, to the three committee members. Based on data from these tests and evaluations, researchers identified 44 "cases of concern" that were referred to the three se...

Biomarkers may hone anti-aging therapies

...d deletion mutations will now go into "Mitomap," a database of all known human mitochondrial genome changes. "Unraveling the molecular clues as to why aging cells function differently than young cells requires that we have molecular markers that we can track," Sligh said. "It won't be long before other inves...

New strategy rapidly identifies cancer targets

...ted software then sifted through a massive protein database at the National Library of Medicine, identifying each of the team's peptides as a segment of a specific protein. The analysis showed that many of the peptides came from tyrosine kinases. Scanning this list, Druker picked out five as likely suspects. ...

MatBase -- A new transcription factor knowledge base released by Genomatix

...tory regions. "We have developed our in-house TF database now for more than a decade", says Kornelie Frech, Genomatix´Head of Biological Databases." Quality is essential for all further downstream analyses. Our quality standards were the key to success for MatInspector, the de facto gold standard in gene pr...

New research finds surveys of larval-stage organisms effective for measuring marine biodiversity

...random sampling of stomatopod larvae to a sequence database of most known mature species of mantis shrimp. The comparisons revealed numerous new varieties of shrimp that are completely unknown in their adult forms. "Our results show that biodiversity in mantis shrimp in these regions is estimated to be at l...

Biologists find regions of rice domestication

...ographic domestication. He said that by using the database that they've gathered, they could design a sampling to target specialty rices such as the aromatic rices basmati and jasmine. For instance, one direction that the researchers are going is Thailand, where the Karen tribe has been using multiple landr...

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