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Tag: "damaged" at biology news

Selectively blocking inflammatory signals may protect mice from MS

...e already studying the use of stem cells to repair damaged myelin sheaths, but in the long term those stem cells would be vulnerable to ongoing immune-mediated damage. But if stem cells could be engineered to resist harmful signals such as interferon-gamma, they might be protected from the "harsh environm...

Healing the heart with bone marrow cells

...ole of bone marrow adult stem cells in repairing a damaged heart, restoring its function and enhancing the gr...ay in The Journal of Clinical Investigation. "When damaged heart tissue sends out an 'SOS' distress signal, this subset of bone marrow cells mobilizes quickly ...

OHSU study says stem cell 'fusion' occurs in tumors

...e marrow-derived cells in not only regeneration of damaged tissue, but also disease progression. "It's the f...ay be at work in regenerating rapidly turning over damaged tissue, or may even be implicated in disease progression. "The intestinal lining is the protective ...

A surprise about our body clock

...ole of bone marrow adult stem cells in repairing a damaged heart, restoring its function and enhancing the gr...ay in The Journal of Clinical Investigation. "When damaged heart tissue sends out an 'SOS' distress signal, this subset of bone marrow cells mobilizes quickly ...

Cutting calories slightly can reduce aging damage

...ing DNA and for protein synthesis, is more quickly damaged by aging than the more frequently studied DNA. RNA damage, therefore, could be an excellent early signal to indicate the onset of aging, researchers say. "Because it is more sensitive to oxidative stress, RNA can be useful as an early marker of oxid...

Protein's role in regulating cell death sets direction for cancer research

...f from their oxygen supply because of a stroke, or damaged by amyloid deposits, this might seem like a bad th... "On the other hand, when a cell's chromosomes are damaged by carcinogens or ultraviolet light in a way that could initiate cancer, this same programmed cell d...

Important gene controlling tree growth and development found

...n the supply of water is low and the tree might be damaged from both drought and cold. The trees have adopted to these conditions by stopping growth and forming buds at the end of summer or early fall. Decidious trees also shed their leaves. The tree is now dormant and is as such much more resistant to droug...

New technology enables faster, more efficient cell harvest: Cell therapy meeting study

...ment of therapies to repair or replace diseased or damaged tissues and organs, was found to be more efficient...lieve cell-based therapies could be used to repair damaged heart muscle following a heart attack, replace skin for burn victims, restore movement after a spina...

Embryos exposed in 3-D

...ment of therapies to repair or replace diseased or damaged tissues and organs, was found to be more efficient...lieve cell-based therapies could be used to repair damaged heart muscle following a heart attack, replace skin for burn victims, restore movement after a spina...

Worm links cancer risk to ageing

...ns by ensuring that cells don't divide if they are damaged also determine lifespan in the nematode worm," explained Professor Gordon Lithgow, who carried out the work at The University of Manchester. "Our research has shown that these 'checkpoint proteins' ?thought only to operate in cells that divide ?func...

Cell wall of pneumonia bacteria can cause brain and heart damage

...orted that in the mouse model, cell wall fragments damaged neurons in the part of the brain called the hippocampus. Tuomanen is senior author of both reports. In the current study, the researchers showed how the cell wall fragments escape the bloodstream and enter cells. Specifically, they demonstrated tha...

Microcapsules like it hot and salty

...rotection agent when damaged, thereby stopping the damaged section from becoming larger. As microsensors they could supply information about the concentration of certain molecules, such as glucose or calcium ions in cells or also work as micropumps. ...

How does a zebrafish grow a new tail?

...ty to regenerate body parts such as those that are damaged by injury or disease," said Dr. Randall Moon, prof...ts can increase the capacity of humans to re-build damaged organs. ...

Most widely used organic pesticide requires help to kill

...ruption of the cells that line the insect gut. The damaged cells, according to the prevailing hypothesis, lead to starvation. An alternative hypothesis holds that the spread of the bacterium in infected insects leads to blood poisoning and death. "It was one of those assumptions built on assumptions -- a s...

St. Jude finds clues to hearing loss from chemotherapy

...of damage that occurs in children whose hearing is damaged by chemotherapy is loss of hair cells in the inner...that goes into the brain. These are the same cells damaged in adults by prolonged exposure to loud noise. "In the future we'd like to be able to prevent the lo...

Buildup of damaged DNA in cells drives aging

...e completely lacking a critical gene for repairing damaged DNA grow old rapidly and have physical, genetic an... ERCC1, is essential for the enzyme to bind to the damaged DNA. Mutations in either XPF or ERCC1 lead to reduced activity of this key DNA repair enzyme. "We...

New target for cancer therapy identified

...without limit which is necessary for the repair of damaged and worn out tissues throughout the human body. However, studies have shown that telomerase also plays a key role in the formation of cancerous tumours. "It's the best indicator of cancer ?85 per cent better than any other tumour marker," Associate...

High levels of blindness in southern Sudan following years of war

...rnea—the transparent front part of the eye—becomes damaged by the eyelashes and develops ulcers, and eventually blindness results. The situation revealed by the researchers is particularly tragic as improved living conditions, better hygiene, and early treatment of the infection with antibiotics can prev...

Neural stem cells lend the brain a surprising capacity for self-repair

...archers found that mice whose brains were severely damaged by loss of the genes "Numb" and "Numblike" in one region just after birth showed substantial mending within weeks. They attributed that repair to neural stem cell "escapees" that had somehow retained or restored the genes' activity and, with it, thei...

Hope for a more effective and less toxic cancer drug

... cells die on cue. If this process fails, then the damaged cells live on and multiply indefinitely and uncont...ally, the cell death machinery is switched on when damaged cells need to be removed. The failure of the machinery to be turned on when it should can lead to ca...

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