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Tag: "damaged" at biology news

A new tool against brain disease

...termine whether these T cells had been irreparably damaged or misprogrammed," he said. "And we found that they are capable of functioning; they've just been turned off." Similarly, the researchers also found that blocking PD-1 restored helper T cell function. "This was the most striking finding, becaus...

Can you hear me now? Scientists find previously unknown receptors on adult stem cells

...ffective means of quickly replacing cells that are damaged or killed while keeping us healthy. But investigators suspect that the system also can be detrimental in certaincircumstances -- for example, in leukemia patients that are vulnerable toinfections after receiving bone marrow or cord blood transplants ...

Slow-frozen people? Latest research supports possibility of cyropreservation

...opreservation, the cells being preserved are often damaged due to freezing of water either on cooling or subsequent warming to room temperature. "Damage of the cells occurs due to the extra-cellular and intra-cellular ice formation which leads to dehydration and separation into the ice and concentrated unfr...

New GI technologies improve internal organ visualization

... may be of specific interest for patients who have damaged heart muscle after a heart attack and may benefit from the injection of therapies directly into the muscle without another operation." Endoscopic Ultrasound (EUS)-Guided Angiography: A Novel Approach to Diagnostic and Therapeutic Intervention in t...

Nicotine exposure during development leads to hearing problems

...ces sensitivity to that sound. If that receptor is damaged due to prenatal exposure to nicotine, acetylcholine cannot bind with it and increased sensitivity to the important sound is lost. "While verbal function cannot be measured in an animal, this establishment of a causal relationship between prenatal n...

Heal thyself: Systems biology model reveals how cells avoid becoming cancerous

...dly identify the damage, stop dividing, excise the damaged DNA, and use several alternate methods to substitu...on network was involved, as expected, in repairing damaged DNA. However, they were surprised to find that a much larger part of the network is involved in modu...

Pollution threatens coral health by preventing lesions from healing, UCF study shows

...n, a small protein that attaches itself to already damaged proteins and causes them to degrade more, also wer...o produce, leaving less energy available to repair damaged tissue. Fauth's team is sharing data with Professor Michael Risk of McMaster University in Ontario...

Schepens scientists are first to discover angiogenesis switch inside blood vessel cells

... body for pregnancy and increases circulation in a damaged heart. But, it can also nourish cancer tumors and ...lar degeneration, or designed to increased it in a damaged heart," he says. Next steps for the research team include identifying the signaling events by whic...

Recombination protein dynamics observed with single monomer resolution

...cA, a protein that plays a major role in repairing damaged DNA. The protein forms a filament, which grows and shrinks primarily by one monomer at a time, the researchers report in the August issue of the journal Cell. RecA is a DNA recombination protein found in the gut bacterium E. coli. A human homolog, ...

Bedsores and bald hides: Novel roles revealed for a 'scaffolding' protein

...r understanding of the role of the cytoskeleton in damaged cells," Coulombe says. When the skin of normal mice is wounded, the skin cells surrounding the wound make more K17 protein and more proteins in general, and become much larger than intact skin cells. Mice lacking the K17 protein are slower at heal...

When it comes to gene transcription, random pauses aren’t quite so random, study finds

... substituted for a C, for example--could produce a damaged protein that causes a serious disease or birth defect. Transcription, the first step in protein synthesis, begins when an RNAP enzyme unzips a small section of the DNA double helix where a gene is located. The enzyme then builds a new complementary...

'Pinball protons' created by ultraviolet rays and other causes can lead to DNA damage

Researchers have known for years that damaged DNA can lead to human diseases such as cancer, but how damage occurs--and what causes it--has remained less clear. Now, computational chemists at the University of Georgia have discovered for the first time that when a proton is knocked off one of ...

Acidity in the brain could hold the key to stroke treatment

...ill be used to compare healthy (neutral, pH 7) and damaged (acidic, lower pH) areas of the brain, and to measure how the pH of the brain changes over time, with the aim of providing more targeted and effective treatments. Professor Morris said: "Within two to three years we hope to have developed an NMR tec...

Global warming may have damaged coral reefs forever

...t term, the main long-term impacts are down to the damaged reefs being largely unable to reseed and recover. Many simply collapsed into rubble which became covered by unsightly algae. The collapse of the reefs removed food and shelter from predators for a large and diverse amount of marine life - in 2005 ...

New research promising for improving brain cell survival after brain injury

...ll's waste disposal system to flush away toxic and damaged proteins produced after injury, which appears to tip the balance towards nerve cell survival, instead of death," he said. Prof Tan is the first to show that this mechanism can be fruitfully manipulated to prevent brain cells from dying. For this r...

University of Minnesota researchers take new look at cellular suicide

...optosis, and its purposes include not only culling damaged cells but shaping an embryo by getting rid of webbing tissue between fingers and toes. By contributing to the understanding of how apoptosis works, the researchers, led by Zigang Dong of the university's Hormel Institute in Austin, Minn., hope someda...

New study shows antibiotic may protect the heart

...ts can be utilized in patients to favorably affect damaged heart muscle beyond the blockage causing a heart attack," said George W. Vetrovec, M.D., chair of cardiology at VCU's School of Medicine, and co-author of the study. For the last several years, Kukreja and his colleagues have studied a class of erec...

Bone marrow may restore cells lost in vision diseases

... "In people, retinal pigment epithelium can become damaged with age," said Jeffrey Harris, a graduate student in the department of molecular cell biology in UF's College of Medicine and first author of the paper. "Factors like smoking and diet also come into play. The problem is without these cells, the rods...

Medium is the message for stem cells in search of identities

...aken from patients, cultured and transplanted into damaged brain environments to restore functions lost to disease or injury. "We largely keep the brain cells we are born with for life, but we also have stem cells in our brain that can divide and make new neurons for maintenance," said Gordon Fishell, Ph....

Birds going extinct faster due to human activities

...aken from patients, cultured and transplanted into damaged brain environments to restore functions lost to disease or injury. "We largely keep the brain cells we are born with for life, but we also have stem cells in our brain that can divide and make new neurons for maintenance," said Gordon Fishell, Ph....

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