Scientists use gene transfer technology and common virus to block neuropathic pain
...be used to block transmission of pain signals from damaged nerves to the brain." After removing genes that make it possible for the herpes simplex virus to infect a human host, VA/U-M scientists use it as a carrier to deliver GAD to the nucleus of nerve cells in the dorsal root ganglion near the spine. In p...New study finds how cells with damaged DNA alert the immune system
...eptor on natural killer cells and are used to flag damaged cells for destruction. There are several types of ...w about our study is that we found that cells with damaged DNA can also involve other cells in the fight, triggering a mechanism that signals other cells - spe...Renewed hope for Parkinson's patients
...eptor on natural killer cells and are used to flag damaged cells for destruction. There are several types of ...w about our study is that we found that cells with damaged DNA can also involve other cells in the fight, triggering a mechanism that signals other cells - spe...UT Southwestern researchers discover master switch in cell death
...ht amount of Mcl-1. Too little Mcl-1 can lead to a damaged immune system or even death. Too much, and cells stay alive when they shouldn’t, leading to cancers such as lymphomas. Using human cell extracts, the researchers found that Mule caused a protein called ubiquitin to bind to several sites on Mcl-1. Wh...Scientists get first glimpse at how plants, most animals repair UV-damaged DNA
...tand how the DNA in plants and some animals can be damaged by UV light, and then ?seemingly ?repaired by visi...ism for photolyase ?that it donated an electron to damaged DNA ?but nobody could prove it. The reaction happened too fast to be seen with normal laboratory too...OHSU researchers discover potential mechanism to repair brain damage linked to Multiple Sclerosis
... revealed that there is a particular signal in the damaged brain that prevents these cells from restoring los...in in the brain, were prevented from repairing the damaged myelin when there were elevated levels of HA," explained Bebo. "By studying another mouse model in m...Molecular Partners Required For Appropriate Neuronal Gene Repression
... revealed that there is a particular signal in the damaged brain that prevents these cells from restoring los...in in the brain, were prevented from repairing the damaged myelin when there were elevated levels of HA," explained Bebo. "By studying another mouse model in m...Researchers discover key to human embryonic stem-cell potential
...fy the circuitry of embryonic stem cells to repair damaged or diseased cells or to make cells for regenerative medicine," says Young. "They also establish the foundation for solving circuitry for all human cells." ...Research casts doubt on circulating stem cells
..., constantly moving through the body and replacing damaged tissue. Even severe diseases like Duchenne muscula...m cells will find their way through the blood into damaged muscle fibres where they can produce functioning dystrophin. The Bonn researcher team was in fact ab...Bone marrow stem cells may heal hearts even years after heart attacks
...t into action, or perhaps fuse with and revitalize damaged heart muscle cells. "It should be noted that unti...ing, processing and delivering stem cells into the damaged muscle tissue of heart attack patients. Piero Anversa, M.D., from the New York Medical College in ...Researchers use brain scans to predict behavior
...at the reward systems' predictive abilities may be damaged or missing in some patients with mental illness, causing these patients to perceive the world as alien and unpredictable. Other areas involved in prediction included regions in the visual cortex involved in the analysis of the motion display and re...Chernobyl: The true scale of the accident
...l elements of the sarcophagus built to contain the damaged reactor have degraded, posing a risk of collapse a...otopes were deposited within 100 kilometers of the damaged reactor. Radioactive iodine, of great concern after the accident, has a short half-life, and has now...... organic compounds called phenols that leak out of damaged cells when a plant is wounded. A bacterial protein called VirA acts like an antenna, detecting phenols in a plant wound; the phenols, in turn, signal VirA to add a phosphate (PO4) group to a related protein, VirG, converting it into an active form. ...Stem cells' electric abilities might help their safe clinical use
...imited supplies of healthy, specialized cells into damaged organs. "We do not want to be taking any chances of tumor formation. Based on our previous research, we therefore decided to explore the existence of ion channels in pluripotent, or versatile, human ESCs because electrical activity is known to regul...Normal chromosome ends elicit a limited DNA damage response
...the Regulatory Biology Laboratory. In contrast to damaged strands of DNA, they hypothesize, the repair process never gets fully underway at telomeres. Instead, the very tips of the chromosomes are looped back, tucked in and covered with telomeric proteins. "The cell tries to fix everything to make sure tha...Logging doubles threat to the Amazon, rivaling clear-cutting, study suggests
...02, selective logging added 60 to 128 percent more damaged forest area than was reported for deforestation alone in the same study period. The total volume of harvested trees represents roughly 10 to 15 million metric tons of carbon removed from the ecosystem, according to the authors. They estimate that th...Pillows - a hot bed of fungal spores
... to people with allergic diseases of the lungs and damaged immune systems - especially those being sent home from hospital." Professor Ashley Woodcock added: "Since patients spend a third of their life sleeping and breathing close to a potentially large and varied source of fungi, these findings certainly h...Scientists discover the molecular switch for nerve cells' insulating jelly rolls
...f so, it may one day be possible to enhance or fix damaged spinal cords and brain tracts that have lost their myelin due to injury or disease by transplanting into, or turning on, a functioning neuregulin gene in nerve cells. "Is it possible that this same switch can reprogram a nerve cell that has lost myel...MIT researcher finds neuron growth in adult brain
... day be possible to grow new cells to replace ones damaged by disease or spinal cord injury, such as the one ...used mostly on trying to regenerate the long axons damaged in spinal cord injuries, the new finding suggests targeting a different part of the cell: the dendri...... amyotrophic lateral sclerosis, or nerves that are damaged by trauma or injury. In none of these systems are new neurons formed or integrated to any great extent naturally. ...