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Tag: "damaged" at biology news

Stem cell therapy successfully treats heart attack in animals

...r pig's bone marrow and injected into the animal's damaged heart restored heart function and repaired damaged heart muscle by 50 percent to 75 percent. The Hopkins findings, first presented last fall at the 20...

Combination therapy leads to partial recovery from spinal cord injury in rats

...wth of new "insulation" around nerve fibers in the damaged spinal cords of rats, a new study shows. The treat...ve any electrical activity that passed through the damaged spinal cord. Studies of the damaged spinal cord tissue after the combined treatment showed that many...

New method shows it is possible to grow bone for grafts within a patient's body

...iably in one part of the body and use it to repair damaged bone at a different location. The research, which is based on a dramatic departure from the current practice in tissue engineering, is described in a paper titled "In vivo engineering of organs: The bone bioreactor" published online next week by the...

Researchers grow stem cells from human skin

...he potential of stem cells and use them to replace damaged cells and tissue in conditions such as spinal cord...ll in the gaps in bone fractures or replace muscle damaged by injury. "The ability to engineer tissues from a patient's own cells may overcome two major probl...

Purdue scientists may have found key to halting spinal cord damage

...cience has long been aware that some chemicals the damaged cells release are part of the problem, but no one ...ur hands in developing PEG, a substance that coats damaged spinal cells so that their membranes can heal and also oscillating field stimulator implants that en...

New complete muscle grown in the lab

...t this hopefully will be used to repair or replace damaged muscle tissue when needed," Levenberg says. In the near future, Levenberg explains, a simple muscle biopsy might provide the "seed" cells for a person's own engineered replacement muscle. For example, the lab-grown muscles could replace tissue lost ...

Insects develop resistance to engineered crops

...ts housed together, all the plants were eventually damaged by the insects, because over time, greater numbers of insects developed resistance to the plants' toxins. However, in the same two-year time frame, all or almost all of the insects died when exposed to pyramided plants alone. "It's easier for an ins...

Pinpointing the cause of a neurodegenerative disorder

...used Ataxin-1 function to be altered in a way that damaged or killed Purkinje cells. "We had been accumulating clues that the glutamine tract expansion is clearly what is important for disease because that's the mutation," said Zoghbi. "But we also concluded that there was something else beyond the glutamin...

Redesigned protein accelerates blood clotting

...cky protein strands that form a web-like clot over damaged tissue. Calcium, a metallic element, must be present for factor VIII to work. Factor VIII has on its surface pocket-like chains of amino acids shaped to hold calcium ions (calcium binding sites). When calcium bonds to it, factor VIII changes shape an...

Woods Hole Research Center plans controlled burn in Amazon rainforest

...has burned a first time, the combination of a more damaged forest canopy and a stock of larger fuel from tree...g branches are very close to the ground and may be damaged if too close to the flames. If their standing dead trunks manage to catch fire, researchers will lea...

Novel mechanism for DNA replication discovered

...mechanism by which cells can replicate through DNA damaged by certain carcinogens. It thus opens a novel area of study with the potential for innovative approaches to prevention and treatment of cancer." ...

Researchers devise new technique for creating human stem cells

...te organs, such as the pancreas or heart, that are damaged by disease or trauma. Stem cells also provide a model system in which researchers can study the causes of genetic disease and the basis of embryonic development. Eggan, Melton and their colleagues decided to pursue their alternative route after othe...

For first time, brain cells generated in a dish

...e large numbers of a person's own cells to restore damaged brain function, partially because the technique produces cells in far greater amounts than the body can on its own. In addition, the discovery pinpoints the cell that is truly what people refer to when they say "stem cell." Although the term is used...

The synapse is a shotgun

...nique, we can explore the detailed geometry of the damaged tissue and ask how much of that anomaly is caused by the geometry itself," he said. "Once we have pinned down where the real problem is, we can use the model as a fantastic tool for drug discovery. We can tell drug developers precisely where the ano...

AACR Favors 'full spectrum of stem cell research biology'

...eir value in replenishing blood and immune systems damaged by cancer or cancer treatment. Research on human e...rs to the differentiated cells needed to replenish damaged tissue. In light of the recent cloning of patient-specific human embryonic stem cells by researcher...

Muscle repair: Making a good system better, faster; implications for aging, disease

...-type plasminogen activator (uPA) was increased in damaged muscle. The result was improved recovery of muscle function and accelerated muscle repair associated with faster increases in proteins such as the myogenic transcription factor MyoD. "In other words, we observed accelerated repair over and above what...

Researchers find molecule that inhibits regrowth of spinal nerve cells

...physically block nerve cells from regrowing in the damaged area, but components of myelin also chemically pre... the middle of the cortical spinal tract, which is damaged during spinal-cord injury. In the current study, Dr. Parada and his colleagues asked: What is this ...

Gradient guides nerve growth down spinal cord

...new connections among neurons to repair or replace damaged nerves. Unlike many other body components, damaged axons in the adult spinal cord cannot adequately repair themselves. An estimated 250,000 people in t...

Scientists use gene transfer technology and common virus to block neuropathic pain in animals

...be used to block transmission of pain signals from damaged nerves to the brain.?/p> After removing genes that make it possible for the herpes simplex virus to infect a human host, VA/U-M scientists use it as a carrier to deliver GAD to the nucleus of nerve cells in the dorsal root ganglion near the spine...

MSKCC researchers uncover structure of key protein complex in cells

...s. Ubiquitin acts as a chemical tattoo that marks damaged or obsolete proteins for destruction by a protein ...uitin marks p53 for destruction. But in cells with damaged DNA, p53 evades getting tagged with ubiquitin to allow its accumulation, thus enabling the p53 suppr...

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