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Tag: "damage" at biology news

Researchers discover why melanoma is so malignant

... melanocytes--cells that protect the skin from sun damage by producing pigmentation--morph into cancer cells, they immediately reawaken a dormant cellular process that lets them travel swiftly throughout the body. Central to this reawakened process is a gene called Slug (named after the bizarre embryo s...

Normal chromosome ends elicit a limited DNA damage response

...e presumably exposed chromosome ends trigger a DNA damage response? Turns out they do, at least to a limit...s found that several well-known members of the DNA damage response machinery ?recruited by the now unprotected telomeres - congregate at the tips of chromosom...

Logging doubles threat to the Amazon, rivaling clear-cutting, study suggests

...ers. When you knock down a tree it causes a lot of damage in the understory. It's a debris field down there." ...

Restoring silenced suppressor gene kills lung-cancer cells

...the death of cells that have sustained serious DNA damage before the cells become cancerous. The loss or silencing of tumor suppressor genes is a fundamental cause of tumor development. The WWOX protein is missing in cells making up many lung tumors, and in 62 percent of cases, the gene is turned off by a...

Breath of the dragon: ERS-2 and Envisat reveal impact of economic growth on China's air quality

...dioxide in large quantities is known to cause lung damage and respiratory problems, although little is known about the consequences of long term exposure to elevated atmospheric amounts. The presence of this gas is a significant driver of the production of low-level ozone, which, within the troposphere (the...

Molecular cabal contributes to stroke damage

...r mechanism linking two key components of neuronal damage due to oxygen starvation, or ischemia. One compone... during ischemia. The other component of neuronal damage that they studied is an "acid-sensing ion channel," (ASIC)--basically, a pore-like protein in the me...

University of Delaware researchers develop cancer 'nanobomb'

...an be spread over a wide area to create structural damage to the cancer cells that are close by. The nanobombs are superior to a variety of current treatments because they are powerful, selective, non-invasive, nontoxic and can incorporate current technology, including microsurgery. An advantage over ...

Scientists discover the molecular switch for nerve cells' insulating jelly rolls

...h as multiple sclerosis, which are associated with damage to myelin. A team led by James L. Salzer, M.D., Ph.D., Professor of Cell Biology and Neurology at NYU School of Medicine, identified the long-sought factor that determines whether or not nerve cells will be wrapped in thick layers of myelin, produci...

Pulp mill devastates swans' sanctuary in Chile

...Human Rights. "The sanctuary has suffered so much damage that we won't know, without more research, how long it may take to restore it. The first priority now should be strict measures to reduce pollution at the source. At the same time, urgent human health and socio-economic impacts must be addressed. Tho...

'Acid rain' and forest mass: Another perspective

...he atmospheric deposition of contaminants produces damage in the forest masses of Bizkaia and may be aggravated in the future. ...

Russian 'surrogate' alcohols are a killer

...d a number of more toxic alcohols that could cause damage to the heart and liver," said McKee. "The medicinal substances were about one and a half times as strong as vodka. The third group, including products such as aftershaves, was more than twice as strong as vodka." Both McKee and Shkolnikov believe...

Polymer gel can block toxic leakage problem in gene therapy

...rough rifts in tiny tumor blood vessels created by damage from the injection needle. Yuan said such viral escapes are inevitable since the needle's diameter is 30 times larger than the width of the microvessels that supply the tumor with blood. The needle is also wider than the spaces between each of those...

Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer

...ss of chemotherapy and radiation, which cause such damage in the course of treatment. In preclinical work, Chang and her group found that the nanoparticle-p53 therapy enhanced chemotherapy and radiation treatment for cancer, pushing damaged cancer cells to die. They have also demonstrated that the nanoco...

Scientists move forward understanding of schizophrenia

...utical company Merck Sharpe and Dohme reveals that damage to the gene PDE4B is also seen to increase the risk of developing mental illness. PDE4B was already known to play an important role in how the brain thinks and builds memories, but had not previously been linked to mental disorder. In addition, resea...

Marine conservation organizations team up to conduct Indonesia coral reefs assessment

...Reef Check and World Conservation Union to examine damage to tsunami-affected coral reefs; mission set to st...ilometers of Aceh's southwest coast to examine the damage to the coral reefs. The survey results will indicate how much of the coral reef structure was damage...

New possibilities for flu antiviral and vaccine research emerge from 'Spanish flu' virus

... to disarm the parts of the virus that do the most damage to the body. In order to learn which components of...emed to be responsible for much of the severe lung damage reported in people infected with the Spanish flu. The three genes encoding the viral "polymerase" en...

Katrina floodwaters not as toxic to humans as previously thought, study says

... more industrial sites in the city and if the wind damage or water surge had been more severe, then the resultant floodwaters could have been a more serious toxic threat, Pardue says. "Instead, the city filled slowly, like a bathtub, and the water velocities and forces on the buildings, including chemical s...

Tsunami + 1 year: Reviving exhausted fisheries should trump replacing boats, gear, experts say

...n of destructive fishing practices; 3. Widespread damage to coastal habitats such as mangroves (and deforestation to support rebuilding efforts) may affect the sustainability of key fisheries resources; 4. History shows us that the continuation of open-access fishery regimes for these coastal communities ...

Stroke treatment a step closer after trial

...search. "In the laboratory we were able to reduce damage to the cells by as much as half; if we could cut cell damage in patients by even a third it would be a very significant step forward in treating stroke." IL-1ra...

Blocking the nerve receptor EP1 in mouse models reduces brain damage caused by stroke

...ow to block a molecular switch that triggers brain damage caused by the lack of oxygen during a stroke. The ...pkins study results suggest that PGE2 causes brain damage following stroke by binding to the EP1 receptor on nerve cells. Therefore, blocking PGE2 activity di...

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