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Tag: "damage" at biology news

Gene therapy for Parkinson's disease moves forward in animals

...ing small monkeys called marmosets prevented brain damage by producing therapeutic levels of a protein that helps nourish brain cells, said Ron Mandel, Ph.D., a scientist with the University of Florida's McKnight Brain Institute and Genetics Institute who was part of the research team. The protein, called ...

Vascular structure and function improve with diet and exercise

...x. Left ventricular mass is a measure of end organ damage often following the onset of LVDF abnormalities. The brachial (arm) and carotid (neck) arteries were tested for intima-media thickness and arterial distensibility. Both reflect the health of the blood vessels. The thicker and less distensible (elast...

Antibiotic might fight HIV-induced neurological problems

...tive of HIV, and treated with minocycline had less damage to brain cells, less brain inflammation, and less ...fection seems to be controlled, it may still cause damage in the brain. And because people are living with HIV longer than ever, the prevalence of neurologica...

Protein offers way to stop microscopic parasites in their tracks

..., kills at least 1 million people per year through damage to red blood cells and clogging of the capillaries that feed the brain and other organs. Cryptosporidium, which causes diarrhea, vomiting and other symptoms, is one of the most common causes of water-borne disease in the world. "These other parasite...

Artifical cornea lets woman blind 20 years see

...ar cornea wouldn't work because of the severity of damage to my corneas. But now my life is more like normal...at I want to read." While many people with cornea damage are eligible to become candidates for standard human cornea transplants, some cannot tolerate donor ...

Potential treatments for neurofibromatosis

...affected by the disease face possible paralysis or damage to the brain and other organs. The disease frustrates doctors because there's no effective treatment even though the responsible gene was identified more than a decade ago. Currently little can be done to treat a disease that affects more people tha...

Surprising findings reported about iron overload

...prevalent in the South, and sometimes causes organ damage when severe iron deposition occurs due to inadequate control of iron absorption by the small intestine. The first major report of findings in the five-year, 100,000-person study will be published tomorrow, April 28, in The New England Journal of Med...

PET/MRI scans may help unravel mechanisms of prenatal drug damage

...ckly provide clues to the underlying mechanisms of damage and suggest ways to test new treatment or prevention strategies," said Benveniste. The imaging tools could also be used to assess the effects of therapeutic drugs, such as administering synthetic narcotics to pregnant women following surgical proced...

Probing the promise and perils of nanoparticles

...y investigating how certain kinds of nanoparticles damage cell membranes---enough to cause cell death in some cases---and how the damage can be prevented. "If you're inventing these sorts of materials, you need to be concerned about the...

Single stem cells from bone heal a broken heart

Myocardial infarction results in irreversible damage to the heart that can cause congestive heart failure. The lasting damage results from the limited ability of the myocardium to regenerate and self-repair. Douglas Losordo an...

Newly discovered pathway might help in design of cancer drugs

... there is a way to efficiently create this type of damage by modifying the DNA itself." In the lab, Greenbe...elength light that selectively switches on the DNA damage process. He said that the synthetic DNA is very similar to that which is produced when cells are ex...

Buying Time Through Hibernation on Demand

...t for a host of human ills related to ischemia, or damage to living tissue from lack of oxygen," said Roth, ...number of amputations caused by irreparable tissue damage from wounds that won't heal. A wound to the skin allows the entry of oxygen, which initiates cell de...

U-M team recovers ancient whale in Egyptian desert

...t for a host of human ills related to ischemia, or damage to living tissue from lack of oxygen," said Roth, ...number of amputations caused by irreparable tissue damage from wounds that won't heal. A wound to the skin allows the entry of oxygen, which initiates cell de...

Researchers uncover sequence of major rice pathogen

...teins that are likely used as offensive weapons to damage rice plants; and redundant, or duplicate, mechanisms that protect the fungus from efforts to fight against it. "It's a clever system," Dean says. "If you have important genes, you tend to have a lot of them." The paper also reports that the M. gris...

Harmful chemicals may reprogram gene response to estrogen

...posure to harmful agents in the environment caused damage to the gene. This study, however, indicates that an environmental agent can actually change or reprogram the gene so that it functions differently. "This study is telling us that an environmental reprogramming of a normal response, combined with an ...

Scientists identify genetic pathways essential to RNA interference

...destruction," says Kim. "And the connection to DNA damage pathways, which was totally unexpected, suggests a potential connection between RNAi and the control of cell division in cancer." The researchers note that better understanding the mechanisms underlying RNAi could help transform what has been a rese...

Protein That Promotes Survival Of Stem Cells Might Be Key To Poor Leukemia Prognosis

...leukemia cells resistant to treatments designed to damage the cell so it undergoes apoptosis." Opferman is continuing his studies of Mcl-1 at St. Jude to better understand the role this protein plays in both normal hematopoiesis (production of blood cells) as well as in potentially fatal blood cancers. Opf...

Yeast Network Prevents Damage By Oxygen Radicals

...seases associated with genetic deficiencies of DNA damage responses." ...

Mystery Blood Vessel Disorder Implicated In 'Mini' Strokes

...ficant cause of lacunar or "mini" strokes that can damage small areas of the brain. Depending on which area of the brain is affected, the strokes can impair functions such as movement, physical control of speech, or coordination. Multiple lacunar strokes can also cause cognitive and memory deficits that re...

Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment

... large. When the egg is thawed, ice crystals cause damage that prevents the egg from being fertilized. U-M ...ch as chemotherapy and radiation therapy can cause damage to a woman's reproductive system and leave her unable to have children afterward. Some women may reg...

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