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Tag: "damage" at biology news

Clinical trial to test stem cell approach for children with brain injury

...l. "All we can do now is try to prevent secondary damage by relieving pressure on the brain caused by the initial injury." Unlike bone, muscle and other organs, the brain does not repair itself effectively. Traumatic brain injury victims can regain some function through rehabilitation. Studies show betw...

New GM mosquito sexing technique is step towards malaria control, report scientists

...re responsible for spreading malaria, and also for damage to crops, but they are only able to breed once bef... have also had side effects, such as environmental damage through insecticides. This advance could one day make a major impact on the burden of ill health cau...

Bare metal stents deliver gene therapy to heart vessels with less inflammation in animal studies

...studies, because of iNOS's ability to control cell damage in blood vessels. "However, in further studies, one might use a combination of therapeutic genes or different gene vectors, for even better results," said Dr. Levy. Metallic implants are already widely used in medicine. Some examples are artificial ...

Evolutionary conservation of a mechanism of longevity from worms to mammals

...istant to oxidative stress and exhibit reduced DNA damage when compared to ES cells in which this gene is active. Because these findings would predict that reduced expression of the mclk1 gene would result in longevity, the authors compared the lifespan of mice heterozygous for mclk1 with their wild-type...

Gene Expression in the Aging Brain

...ory of aging lays the blame on the accumulation of damage done to DNA and proteins by “free radicals,?highly...d by the metabolic activity of mitochondria. This damage is expected to reduce gene expression by damaging the DNA in which genes are encoded, and so the the...

Navigating the brain for sense of direction as paradigm for higher cognitive functions

...ory of aging lays the blame on the accumulation of damage done to DNA and proteins by “free radicals,?highly...d by the metabolic activity of mitochondria. This damage is expected to reduce gene expression by damaging the DNA in which genes are encoded, and so the the...

Carnegie Mellon scientists create PNA molecule with potential to build nanodevices

...ory of aging lays the blame on the accumulation of damage done to DNA and proteins by “free radicals,?highly...d by the metabolic activity of mitochondria. This damage is expected to reduce gene expression by damaging the DNA in which genes are encoded, and so the the...

New brain scan technology could save babies' lives

...oxygen, where blood is situated, evidence of brain damage etc. MONSTIR is the size of a fridge-freezer and takes around 8 minutes to generate an image. The aim is to produce a version that is half this size, 5 times faster, even more accurate and geared for clinical use. The potential use of the technolog...

Finding rewrites the evolutionary history of the origin of potatoes

...such as late blight can cause significant economic damage to farmers in America and throughout the world. "As a taxonomist, my job is to help determine what is a species and to classify those species into related groups," Spooner explains. "Other scientists use these results as a kind of roadmap to guide ...

Limiting the damage in stroke

...F-kB signalling, they discovered, suffer even more damage than normal; far more cells die. But if the IKK2 signal is blocked, damaged cells stay alive and even seem to recover. The effects are long-term; neurons in the damaged tissues were still alive several days after the stroke. Two factors make the stu...

Discovering the first steps in transcription-coupled repair

...nd free radicals from the cellular metabolism. DNA damage ranges from one or a few altered nucleotides in a ... However, in XP there is loss of ability to repair damage to DNA caused by ultraviolet radiation throughout the genome, whereas in CS the global repair mechan...

Brainstem blocks pain to protect key behaviors

... radiant heat to one hind paw. The heat caused no damage but was annoying enough to make the animal withdraw that paw within seconds. When the rats ate, however, they postponed retracting the heated paw for six to eight seconds and continued to eat. Food choice made no difference. Rats focused just...

Common alternative treatment for liver disease is found to be ineffective

...xidation, which is frequent in all stages of liver damage in alcoholic and non-alcoholic liver disease. "The ironic fact is," notes Christian Gluud of the Copenhagen Trial Unit, Center for Clinical Intervention Research at the Copenhagen University Hospital, "that even though milk thistle and milk thistle ...

Anyway you slice it, tomatoes cut through drought with new gene

...atoes used in the experiment suffered irreversible damage after five days without water, as opposed to the transgenic tomatoes, which began to show signs of damage after 13 days but rebounded completely as soon as they were watered, according to the study. "Th...

Health of Acehnese reefs in the wake of the tsunami shows human impacts more harmful

...rch reported this week in Current Biology, tsunami damage to coral reefs closest to the epicenter of the 200...urprisingly limited, particularly when compared to damage from chronic human misuse in the region. Less than 100 days after the tsunami of December 26, 2004...

Scientists show how thinking can harm brain cells

...resistant to future encounters with stress and the damage it can trigger," said Harris A. Gelbard, M.D., pro...amate, however, can overly excite neurons, causing damage and death ?a process called excitotoxicity. Some drugs developed for the treatment of Alzheimer's di...

Texas scientists discover how a hepatitis C protein promotes liver cancer

... an initial infection, often causing so much liver damage that a transplant may be a patient's only chance for survival. The most effective treatment available, interferon therapy, works only about half the time and often causes debilitating side effects. Those who fail treatment are at risk for fatal cirrh...

Preclinical study of a new brain tumor therapy

...nt therefore eliminates the tumor cells but avoids damage to the normal brain tissue. The researchers found that the treatment was effective in mice implanted with human brain tumor cells that overexpressed EGFR. The treatment could eliminate established cancers and there was no evidence of recurrence: th...

Study finds that nutritionally enhanced rice reduces iron deficiency

...plements and other strategies to ease the enormous damage wreaked by iron deficiency and related conditions. Iron deficiency can affect a child's physical and mental development, and each year causes more than 60,000 maternal deaths during pregnancy and childbirth. Recent statistics from the Micronutrients...

Human trial proves ricin vaccine safe, induces neutralizing antibodies; further tests planned

...s develop fever, nausea and abdominal pain or lung damage before dying within a few days of exposure. There is no antidote after the first few hours of exposure and, because symptoms do not appear until later and often mimic other illnesses, individuals often do not know if they have been exposed until it i...

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