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Tag: "cycle" at biology news

Scientists Replicate Hepatitis C Virus in Laboratory

...re will allow researchers to better study the life cycle and biology of this virus and to test potential an...tem only represents the tail end of the viral life cycle ?viral replication, assembly and release from host cells. Another HCV model system is needed to show...

Novel Enzyme Shows Potential As An Anti-HIV Target

...ction in HIV transcription. The authors propose a cycle of transcriptional transactivation in which SIRT1 deacetylates Tat at the HIV promoter. Deacetylated Tat associates with CyclinT1 and TAR, and leads to transcription. Tat acetylation dissociates Tat from CyclinT1 and TAR, and transfers Tat to the elo...

Molecular machine may lead to new drugs to combat human diseases

... Two intron structures in different stages of the cycle have been crystallized previously, and the targeted trans-splicing technique has been used to repair hemoglobin infected with sickle cell anemia. The new structure provides scientists with tools to expand on ways to harness this molecular machine, Go...

A bacterial genome reveals new targets to combat infectious disease

...omises the nematode's ability to complete its life cycle within its human host. Thus, understanding the details of this relationship may help identify new strategies for controlling diseases caused by filarial nematodes. In a new study published in the freely-available online journal PLoS Biology, Barton S...

Scientists reveal molecular secrets of the malaria parasite

...tvectors.That focus on the parasites' complex life cycle is helping researchersunderstand when different genes switch on and off as the pathogensmetamorphose through seven different life stages. In turn, thatmolecular-level data may benefit biomedical scientists who areidentifying new targets for vaccines ...

Nano-Probes Allow an Inside Look at Cell Nuclei

... as DNA replication, genomic alterations, and cell cycle control. The long-lived probes may also allow researchers to track the effectiveness of disease-fighting drugs that target these processes. "We could determine whether a drug has arrived where it is supposed to, and if it is having the desired impac...

Scientists discover that host cell lipids facilitate bacterial movement

...The bacteria then enter the new cell and begin the cycle anew. Essentially Listeria takes over or hijacks the host cell's actin cytoskeleton to move within cells, and to spread from cell to cell." In most cells, two membrane lipids, PIP2 and PIP3, are associated with the formation of new actin filaments. ...

Effective Cancer Treatments Follow The Clock

... on a 24-hour, circadian (Latin for "about a day") cycle that governs functions like sleeping and waking, rest and activity, fluid balance, body temperature, cardiac output, oxygen consumption and endocrine gland secretion. In their experiments, the researchers measured the animals' body weight as an indi...

Yale researchers identify molecule for detecting parasitic infection in humans

...dii) causing toxoplasmosis, has a complicated life cycle in which it is transmitted from mice to cats and then to humans. Previous research had shown that T. gondii is recognized by a TLR and that the recognition of this parasite is crucial for an appropriate immune response. However, it was unclear which ...

Epstein-Barr virus protein crucial to its role in blood cancers

...?called EBNA3C (for EBV nuclear antigen) ?the cell cycle of the usually quiescent human B cells gets a jump... associated with cancers typically target the cell cycle to gain control," says Robertson. "However, this is the first time that laboratory research into how...

Defensins neutralize anthrax toxin

...?called EBNA3C (for EBV nuclear antigen) ?the cell cycle of the usually quiescent human B cells gets a jump... associated with cancers typically target the cell cycle to gain control," says Robertson. "However, this is the first time that laboratory research into how...

Researchers identify protein crucial for survival of Lyme-disease bacterium

...tain itself, then in theory you could disrupt that cycle by blocking whatever that mechanism is," Dr. Norga...coin. "This organism has to live half of its life cycle in a tick," he said. "There must be subsets of genes important to its survival there. If it can't ex...

GeneNotes - A novel information management software for biologists

...human-computer interfaces that greatly shorten the cycle of biology research. ...

First frozen egg baby born in Canada

...d too many follicles in her ovaries, the treatment cycle had to be cancelled because of a high risk of mult... egg donor programs require matching the menstrual cycle of egg recipients; this problem can be eliminated with egg freezing. ...

Super predators and mass extinctions

...e to fill the existing ecological niches - and the cycle begins again. The period of the cycle depends on mutation rates in the model. The lower the mutation rate, the longer the periods between ...

Yeast Network Prevents Damage By Oxygen Radicals

...ve identified a key network of DNA repair and cell cycle control genes in yeast that prevents the deleterious effects of ROS. "DNA repair and cell cycle control mechanisms are important guardians against cancerous changes in human cells," says Dr. Richa...

Same-Sex Mating Discovered in a Toxic Fungus

...th a conundrum. C. neoformans has a defined sexual cycle involving both mating types. "Yet, how can sexual reproductive potential be maintained in an organism with a largely unisexual population structure?" Heitman asked. "The fruiting of alpha strains provided a clue." In their laboratory experiments, th...

New understanding of DNA repair may pave way to cancer treatments

...egulating expression of proteins that control cell cycle and programmed cell death is well established. The...al of understanding its role in regulation of cell cycle and programmed cell death. These studies evolved from the finding that ATF2 has an important role in...

Anammox bacteria produce nitrogen gas in oceans' snackbar

...rm new nutrients that can be fed into the nutrient cycle again. In the article in PNAS, researchers from t...nitrogen loss has also consequences for the carbon cycle in marine ecosystems. Denitrification. The measurements refute the dominating theory that oceanic n...

Africa to take it on chin again with climate change

...c than in the North, it pulls the Sahelian monsoon cycle south as well, depriving the region of its usual rains. "This was the situation during much of the latter half of the 20th century." says Hurrell. "We believe the North Atlantic Ocean cooling was natural and masked an expected greenhouse-gas warming...

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