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Tag: "current" at biology news

Viral protein influences key cell-signaling pathway

... affects the activity of a variety of genes." The current study used a non-infectious form of HIV to transplant the HTLV-1 p12 gene into laboratory-grown T cells. The infected cells then produced a constant level of p12 protein. The researchers then used gene microarray technology to identify which cellular...

Molecular models advance the fight against malaria

...could suppress malaria's ability to mutate against current therapy. "This is the first quantitative explanation for malaria's drug resistance," said Dr. Bernard Trumpower, professor of biochemistry at Dartmouth Medical School and head of the study. "In addition to confirming the belief that the resistance wa...

Discovery Promises Simpler Therapy for Sickle Cell Disease

...cks, septic shock and sickle cell disease. In the current study, the researchers found that hemoglobin in the red cells of patients with sickle cell disease fails to process nitric oxide properly. As a result, they reported, the membranes of sickle red blood cells are deficient for the form of nitric oxide ...

Molecule that usually protects infection-fighting cells may cause plaque deposits inside arteries

...d the protective role of AIM six years ago. In the current study, scientists exposed mice lacking AIM to a fatty diet that would normally induce atherosclerosis. After several weeks, researchers found little to no atherosclerotic lesions. Comparatively, in mice that had normal AIM function, there was marked...

Institute for Systems Biology Symposium Addresses Need for Better Computational Tools

...s approximately 100,000 years to complete with the current computational power at ISB. We have already predic...oftware Engineer at IBM Global Services, outlining current efforts to run Rosetta de novo structure prediction on World Community Grid, and applications of thi...

Insight into natural cholesterol control suggests novel cholesterol-lowering therapy

... at much greater concentrations, they found. "The current results demonstrate a direct role for lanosterol as a selective, physiologic regulator of reductase ubiquitination and degradation," said DeBose-Boyd. That effect would, in turn, control the rate of cholesterol production. "In addition to the biolog...

No relief for Pacific Northwest drought

... through the end of last January. In terms of the current projections for a tier of states in the northwestern U.S., it appears the situation is going to go from bad to worse. It bears some similarity to conditions last seen in 2001. "We use five different global climate models as the underlying basis for ...

Marburg haemorrhagic fever in Angola update

... suspicions about the safety of hospitals. In the current outbreak, such suspicions are understandable. Very few patients with laboratory-confirmed Marburg haemorrhagic fever have survived; most hospitalized patients have died within a day or two following admission. For affected communities, staff from the...

Alzheimer's cognitive decline slowed

...resent a substantially more effective therapy than current treatments for Alzheimer's disease," said Mark Tuszynski, M.D., Ph.D., UCSD professor of neurosciences, neurologist with the VA San Diego Healthcare System, and the study's principal investigator. "This would also represent the first therapy for a hu...

Survey finds silver contamination in North Pacific waters

...hout the world's oceans. The goal was to establish current levels of contamination as a baseline for future studies, Flegal said. "We found by far the highest levels of silver in the North Pacific. Even though the Atlantic Ocean is subject to industrial emissions from North America and Europe, the amounts a...

Strongest proof yet found for prion hypothesis

...blood test for prions, which would greatly improve current surveillance techniques for mad cow disease and its human form, new-variant Creutzfeldt-Jakob Syndrome. ...

Researchers make gains in understanding antibiotic resistance

...d by Steitz and colleagues at Yale. "About half of current antibiotics target the ribosome, and most of them target the large subunit," he said. "So, such advances have the potential for significant clinical impact. The general strategy of Rib-X to overcome resistance is to create new hybrid antibiotics that...

First frozen egg baby born in Canada

...higher in babies produced by older women. Finally, current egg donor programs require matching the menstrual cycle of egg recipients; this problem can be eliminated with egg freezing. ...

Scientists identify genetic pathways essential to RNA interference

...o viral infection, among other functions. For the current study, lead author John Kim, PhD, and his colleagues developed a strain of C. elegans into which they added a gene that caused the worms to glow under ultraviolet light but also turned that gene off using RNAi. They then used RNAi to inactivate every...

FDA Announces Series of Changes to the Class of Marketed Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

... already addresses potential skin reactions. This current reexamination of the CV risks of NSAIDs began after Merck conducted a voluntary worldwide withdrawal of its COX-2 selective NSAID, Vioxx (rofecoxib), in September 2004. FDA will carefully review any proposal from Merck for resumption of marketing of ...

Defenseless plants arm themselves with metals

...icylic acid in their tissues all the time. In the current study, Salt and his colleagues compared salicylic ...ear it." Salt and his colleagues also show in the current study that salicylic acid induces production of a molecule called glutathione, a potent antioxidant ...

Growth in biomass could put US on road to energy independence

...roduce biofuels to meet more than one-third of the current demand for transportation fuels, according to the ...rom about 12.5 billion pounds, or 5 percent of the current production of target U.S. chemical commodities in 2001, to 12 percent in 2010, 18 percent in 2020 an...

Human Cells Filmed Instantly Messaging for First Time

...roduce biofuels to meet more than one-third of the current demand for transportation fuels, according to the ...rom about 12.5 billion pounds, or 5 percent of the current production of target U.S. chemical commodities in 2001, to 12 percent in 2010, 18 percent in 2020 an...

Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells

...Results of the St. Jude study are published in the current online issue of Blood. The researchers demonstrated how to overcome significant technical hurdles that have until now slowed development of NK-based therapies for ALL, according to Dario Campana, M.D., Ph.D., a member of St. Jude Hematology-Oncology...

Test for early detection of prostate cancer shows promise

...ment of prostate cancer,?said Getzenberg. For the current study, Getzenberg and colleagues developed a simple test that would detect EPCA in the blood and then measured the EPCA levels in 46 patients, including those with prostate cancer (12 patients), bladder cancer (six patients), colon cancer (two patien...

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