Gene therapy injected into the brains' of mice with Huntington's disease
...s of 40 and 50. There is no effective treatment or cure for this fatal illness that affects 30,000 Americans and places another 75,000 at risk. Kordower says this research, if eventually applied to humans, could help those who have HD or, due to the presence of a genetic test, are known to be destined to......ing mutant gene to restore its normal function and cure the disease, Capecchi and Tvrdik say. Genes that Divided are Now Reunited The study involved what are known as Hox genes, which are like orchestra conductors directing the actions of other genes during development of an animal embryo. Unti...Bedsores and bald hides: Novel roles revealed for a 'scaffolding' protein
... their work - yet - to suggest a way to prevent or cure human baldness. K17 belongs to a family of proteins known as keratin intermediate filaments, which are part of the cytoskeleton, an intricate network of flexible protein fibers that maintain cell shape and strength. By studying mice genetically engi...New stem-cell findings can help the body to cure itself
... the process, which in turn could help the body to cure itself. It has long been known that the new cells are often formed by immature cells known as stem cells, but the mechanism regulating the number of new cells produced has remained something of a mystery. However, in a new study to be published by C...Study reveals how cells destroy faulty proteins in cystic fibrosis
...e out how to get CFTR into the right shape, we can cure the disease," Cyr said. To better understand how to fix CFTR, Cyr's research team at the UNC Cystic Fibrosis Pulmonary Research and Treatment Center focused on identifying the cellular system that disposes of faulty CFTR. The investigators identi...Researchers seek to solve mystery of natural HIV control
...elop a first-generation HIV vaccine, which may not cure or prevent infection but could successfully suppress viral levels. Since this natural ability is so rare, we need to work with collaborators around the world to recruit the number of participants we will need to determine what is going on. "We ex...Septum keeps neurons in synch, can reduce epileptic seizures by 90 percent
...rch gives more insight into how epilepsy occurs, a cure is still years away. "But I would say there is hope," Colom said. "We want to offer people with epilepsy new options," he said, but progress will depend upon funding, he added. Next steps The researchers will repeat the study using animals that a...Fish virus in Northeast spreading to other fish species
...lities do not appear to be changing. "There is no cure for VHSV in fish in an ecosystem as large as the Great Lakes Basin. Given this, it is likely that management practices designed to limit the spread of the virus will be put in place," said Groocock. Although no management decisions have yet been mad...Mass. General study finds potential ovarian cancer stem cells
...dicate these stem-like cancer cells and ultimately cure ovarian cancer. With its potential to maintain the ability to inhibit the proliferation of these cells, MIS may play a role in these new therapeutic approaches," Donahoe says. "We intend to keep searching for stem-like cells in patient tumor sample...African parasite makes component of fat differently from all other organisms
...nglund. "There is tremendous need for new drugs to cure these diseases." ...Cycles of cell death, proliferation key to liver cancer
...ward trajectory, with little hope for treatment or cure through chemotherapy, radiation or other traditional cancer treatments. "We now understand development of liver cancer in mice. Since inflammation drives both damage and regeneration in liver tissue, it is the repeating cycle of damage, inflammatio...New pathways for autoimmune treatment identified
... the i NKT cell population is one possible way to cure autoimmune disease." A lipid purified from sea plants, called alpha-GalCer, is already under study as a way to boost iNKT cell numbers and fight autoimmune disease as well as cancer. i NKT cells' reactivity to alpha-GalCer, prompted the scientists...Radiotherapy advance points way to noninvasive brain cancer treatment
...day lead to less invasive treatment and possibly a cure of this disease. "It's the most lethal cancer the...human clinical trials. "If we do see that we can cure animals from their cancers, then it's worth investigating the molecular biology of this drug and see...Study indicates dramatic rise in antibiotic-resistant community-acquired staph infections
...A may be as simple as employing the tried and true cure of soap and water: "Practice good hygiene," is its primary advice. ...MIT research holds promise for Huntington's treatment
...t of a new treatment for the disease. There is no cure for Huntington's, a neurodegenerative disorder that now afflicts 30,000 Americans, with another 150,000 at risk. The fatal disease, which is genetically inherited, usually strikes in midlife and causes uncontrolled movements, loss of cognitive functi...Drug resistance may travel same path as quorum sensing
...as multidrug resistance, results in the failure to cure the bacterial disease. Even worse, the resistance is not just to one drug, but many because the pump is now increased and many different drugs will be pumped out. "It compounds the problem," said Zechiedrich. Her findings are a step toward understa...St. Jude projects 90 percent cure rate for ALL
The cure rate for the once almost universally fatal childho...l of Medicine. The progressive improvement in the cure rate since 1962, when only 4 percent of children with ALL survived, reflects in large part the more ...Two NIH initiatives launch intensive efforts to find roots of common diseases
... of possible revolutionary approaches to treat and cure diseases. Pfizer, the NIH and other public/private biomedical research interests have complementary missions greater than the sum of their parts. Our hope is that this public/private initiative will encourage a deeper collective understanding of the ...Rice University researchers create 'nanorice'
...rchers devise ways to slow, prevent and eventually cure a disease that affects an estimated 4.5 million Americans. In a study published in the February 28th issue of the Proceedings of the National Academy of Sciences, lead scientist Hani Atamna, Ph.D., found that alterations in the production of heme (......rchers devise ways to slow, prevent and eventually cure a disease that affects an estimated 4.5 million Americans. In a study published in the February 28th issue of the Proceedings of the National Academy of Sciences, lead scientist Hani Atamna, Ph.D., found that alterations in the production of heme (...