Controlling antibiotics and antibiotic resistance in hospitals
...ria; and (3) targeted - prescribed after bacterial culture results identify the bacteria actually causing the infection. The study found that if a hospital had implemented measures to control the duration of administration of an empiric antibiotic, the institution had lower antibiotic resistance rates. ...'GreeneChip' -- New diagnostic tool that rapidly and accurately identifies multiple pathogens
...ed by more traditional and slower methods, such as culture or polymerase chain reaction (PCR). In addition, the GreeneChip was used in the analysis of an unknown sample from a patient with a viral hemorrhagic fever (VHF)-like syndrome. Within six to eight days of infection, Marburg virus causes an acute ...New drug blocks influenza, including bird flu virus
...als." The new drug, which was tested on cells in culture and in mice, conferred complete protection against infection and was highly effective in treating animals in the early stages of infection. Untreated infected animals typically died within a week. All of the infected animals treated with small doses ...Transplanted photoreceptor precursor cells restore visual function in mice with retinal degeneration
...ral years of research using animal models and cell culture systems will still be needed before transplantation can be considered ready for testing in humans. Restoring visual function in animals is an important advance, but the scientists caution that it shouldn't be considered the same as restoring vis...Tarantula venom and chili peppers target same pain sensor
.... Their finding, based on studies of mice cells in culture and live mice, is published in the November 9 issue of the journal Nature. The senior author is David Julius, professor and chair of physiology at UCSF. The tarantula venom targets the heat sensor on nerve cells known as the capsaicin receptor, fi...Living view in animals shows how cells decide to make proteins
...dding that extracting cells and watching them in a culture cannot convey all of these transient changes. Moreover, different cell types within the brain or other organs can exhibit different splicing decisions, Garcia-Blanco said. For example, neurons reside next to glial cells in the brain, yet they expr...Novel experiment documents evolution of genome in near-real time
... The researchers removed samples of cells from the culture and sequenced their entire genomes as a way to find mutations that enabled faster growth. After six days of growth, mutations appeared in the gene for an enzyme that initiates the process of enzymatically breaking down glycerol. Cells with mutation...Growth factor stimulates rapid extension of key motor neurons in brain
...a new way of isolating pure populations of CSMN in culture and found that IGF-1 was a prime candidate for con...two ways of applying IGF-1 ?generally adding it to culture dishes or placing IGF-1-coated microbeads right next to CSMN cell bodies ?both increased the growth ...Research project tackles 'regeneration' gap
...ce and produce large amounts of new brain cells in culture for use as possible replacements for dead or injured cells. The UF project is "bold" because it takes a comprehensive view of regenerative medicine, according to Arlene Y. Chiu, Ph.D., director for scientific activities at the California Institute...Music genes and musical geniuses
...he overall framework of the event is the music and culture of Mongolia, the Festival’s guest Country. Scientific advisory committee G. Barbujani (Ferrara-Italy), D. Drayna (Rockville-USA), T. Fitch (St. Andrews-UK), L. Lopez (Rome-Italy), I. Peretz (Montréal-Canada), D. Pettener (Bologna, Italy). ...Widely used iron nanoparticles exhibit toxic effects on neuronal cells
...nerve growth factor to nanoparticle-laden cells in culture flasks, they observed toxic dose-dependent effects: some cells died, and many of the survivors exhibited a diminished ability to produce neurites. In their experiments, PC12 cells that had not been exposed to magnetic nanoparticles generated three ...Stem cell therapy shows promise in regenerating damaged muscle in heart attack patients
...he patient. Schaer says the cells were grown in culture to very high numbers, allowing a single donor's cells to treat thousands of patients. "The cells have the ability to expand, or multiply, under controlled conditions, and the expanded cells have the ability to develop into different types of cells in...Engineering the heart piece by piece
...nd, because it does not rely on a traditional cell culture incubator, giving the researchers the ability to carefully control the culture environment of the cells during heart muscle formation and foster a higher degree of functionality. ...New culture method for hepatitis C virus uses primary hepatocytes and patient serum
...udy of hepatitis C virus by devising a novel virus culture system that allows replication of patient-isolated...tes, has been hampered by a lack of adequate virus culture systems. Some systems allow the virus to infect cells but do not permit prolonged replication and p...New evidence of 'human' culture among primates
...t until now there has been no evidence of material culture among the "new world" primates of Central or South...earch is that it suggests an element of human-like culture within this family of Capuchins. Biological anthropologists are divided over whether other specie...Stem cell identity in culture may strongly depend on the cellular microenvironment
Identification, isolation and large scale culture of stem cells for potential medical applications i...mputer simulations, that the stem cell identity in culture may strongly depend on the cellular microenvironment. These observations are in line with the curr...Lab research may one day lead to cancer treatment using patient's own immune cells
...ents, activating these T cells and growing them in culture in the laboratory over one to two weeks. The T cells are activated with molecular agents called interleukin-2 and anti-CD3 antibody (OKT3). It is hoped that results from this research could lead to a safety study, called a Phase I study, in huma...Penn researchers replace organ in adult mice using 'single-parent' stem cells
...em cells from embryonic stem cells entirely in the culture dish before transplanting them. The Penn researchers believe that using uniparental embryonic stem cells as a tissue source could provide a major advance in the alleviation of human disease, provided these results can be translated into human stud...Birth rate, competition are major players in hominid extinctions
...ake advantage of whatever food was available. But culture did not seem to help the Neandertal. Tremendously successful from about 200 to 50 thousand years ago, they suffered a gradual decrease and extinction from about 30 to 26 thousand years ago. "Neandertal was extremely adept culturally," says Jablon...... team investigated the gene's function. Using cell culture studies, they discovered that decreasing the amount of SORL1 increased cells' production of amyloid-beta, a toxic fragment of another protein that destroys neurons. Production of amyloid-beta is the key event in the progression of Alzheimer's disease...