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Tag: "culture" at biology news

A simple feedback resistor switch keeps latent HIV from awakening

...of the model was then precisely replicated in cell culture experiments. An array of cell culture experiments perturbing the supposed Tat resistor was then performed. For example, inhibition of the ...

New evidence of early horse domestication

...snyi Yar site was inhabited by people of the Botai culture of the Eurasian Steppe, who relied heavily on horses for food, tools, and transport. "There's very little direct evidence of horse domestication," says Sandra Olsen, an archaeologist and horse domestication researcher at the Carnegie Museum of Natur...

Human testis harbors HIV-1 in resident immune cells

...infection by HIV-1. Virus produced from the testis culture was fully active as collected virus was able to in... testis, is gravely needed. The use of this testis culture system may allow assessment of new anti-retroviral drugs that target HIV in the testis. ...

How blood flow dictates gene expression

...has been known for decades. More recently, tissue- culture studies have shown that Klf2 is activated by increased blood flow, or "fluid sheer stress." Indeed, in this study Kahn; first author John S. Lee, MD, PhD, Instructor in the Department of Medicine; and colleagues show that the expression of Kl...

Cancer stem cells linked to radiation resistance

... researchers said. Working with animal and cell culture models, the researchers found that a specific cellular process called the "DNA damage checkpoint response" appears to enable cancer stem cells to survive exposure to radiation and to switch on a signal to automatically repair any damage caused to the...

Study finds the air rich with bacteria

... are present in an air sample. In this method, the culture media is exposed to the sample, and whatever grows is counted. Unfortunately, this approach leaves out all of the organisms that can't survive in the culture, which in some cases is as much as 99 percent of the bacteria in a sample. In this censu...

Therapeutic role found for carbon monoxide

...ents, we had the cells separated into two separate culture dishes ?endothelial cells in one, smooth muscle cells in the other," explains Otterbein. But, he adds, when they exposed these cultures to carbon monoxide, nothing happened. The cells behaved normally. "We eventually asked ourselves, 'What if we're ...

Stem cell activity deciphered in the aging brain

...chers also are grafting neural stem cells grown in culture dishes into the hippocampus, to stimulate those already present. Additional approaches include using behavioral modification techniques, such as physical exercise and exposure to an enriching environment, that are known to stimulate proliferation of ...

Microbe fixes nitrogen at a blistering 92 C

...ays. Known as FS406-22 because of the fluid and culture samples it came from, the archaeon discovered by the UW researchers is the first from a deep-sea hydrothermal vent that can fix nitrogen, says Mehta, first author on the Science paper. It was collected at Axial Volcano on the Juan de Fuca Ridge off...

A natural chemical found in strawberries boosts memory in healthy mice

...nts, for their neuroprotective abilities in tissue culture models of neurodegenerative disease. Maher found that some of those compounds, including fisetin, induced differentiation or maturation of neural cells. Maher explains, "That suggested to us that these compounds might be particularly beneficial, s...

Embryonic stem cells do better on bumpy nanoscale mattress

...onths of a meter in altitude. The HES cells in culture seemed to appreciate the bumps. A line of HES cell... far better than HES cells plated on standard flat culture surfaces, according to Daniel McFarlin, K.J. Finn, and Chris Murphy of the University of Wisconsin’...

Faster, more accurate tuberculosis test developed

...ent gold standard TB tests-- the Lowenstein-Jensen culture and automated mycobacterial culture (using the MBBacT system). In order to test the samples using MODS, the researchers observed the cul...

Stem cells found in adult hair follicles may provide alternative to embryonic stem cells

...ge as multipotent stem cells, and then expanded in culture into millions of cells without losing stem cell markers. "We grafted the cells into mice that have spinal cord injuries and were encouraged by the results. The cells survived and integrated into the spinal cord, remaining at the site of transplant...

Developing uses for sugar-cane bagasse: Biotechnology applied to the paper industry

...time yields a delignifying enzyme, laccase, from a culture of a filamentous fungus and effectively recycles the sugar-cane bagasse. Its principle lies in the specific metabolic characteristics of this fungus, Pycnoporus cinnabarinus, which produces laccase naturally. This enzyme breaks down the lignin in the...

Muscle and bone from an ink-jet printer

...ng down patterns on fibrin-coated slides placed in culture dishes containing MDSCs. Based on pattern, dose, o...- and bone-like tissues simultaneously in the same culture dish. The long-term promise of this new technology could be the tailoring of tissue-engineered regen...

From managing sugar to managing healing

...red that insulin stimulates human keratinocytes in culture to proliferate and migrate. In cultured human microvascular endothelial cells, the insulin stimulates only migration into the wound tissue. The insulin works by switching on cellular signaling proteins called kinases (specifically Src, PI3K, and Akt)...

Using nature's most primitive anti-viral defense system to find new approaches to cancer research

...screens with the functional analysis in human cell culture models of metastasis, we expect to identify novel, conserved proteins involved in cell migration and invasion, some of which could prove to be good anti-cancer drug targets." According to Dr Mark Matfield, AICR's scientific adviser: "Metastasis of...

Lab-on-a-chip could speed up treatment of drug-resistant pneumonia

...d to identify bacterial strains by growing them in culture first. At this week's AVS 53rd International Sympo...fection traditionally requires growing the bugs in culture first, a procedure that can take two to three days. Meanwhile, doctors often have no other option th...

Key to lung cancer chemo resistance revealed

...immel Cancer Center, who published results of cell culture studies in the October 3, 2006 issue of PLoS Medic...l cells, according to the researchers. Their cell culture tests also show that cancer cells with KEAP1 mutations are more resistant to chemotherapy drugs than...

Study IDs protein that inhibits HIV from growing in cell cultures

...ein made by GBV-C that inhibits HIV growth in cell culture strengthens the argument that GBV-C is responsible for the prolonged survival observed in several studies of HIV-positive people," Xiang said. "Understanding how the protein works may allow us to develop target-specific therapies that can mimic these...

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