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Tag: "culprit" at biology news

The insect vector always bites twice

...ins contained in an extract of total saliva of the culprit vector. This approach, based on the studies of malaria transmission by mosquitoes of the genus Anopheles and human African trypanosomiasis (sleeping sickness) by Glossinia species or tsetse flies, revealed that the antibody response can represent...

Newly discovered antibody may be body's natural defense against Alzheimer's

...ntists to speculate that oligomers may be the main culprit in Alzheimer's and therefore a prime target for a new generation of disease-modifying treatments. To further confirm that these natural antibodies bind with oligomers, Dr. Relkin and his colleagues collaborated with Drs. Charles Glabe and Rakez K...

Fighting influenza & co. with 40,000 blood samples

... be due to a long-forgotten infection. A suspected culprit is the virus causing Pfeiffer's glandular fever, for example. Due to the age group that is mainly affected and a possible path of infection, this disease is also known as 'Students' Kissing Fever'. After the symptoms have disappeared, the pathogen, t...

Temple University Hospital investigates treatment for cervical dysplasia

...can lead to more serious problems and are the main culprit for cervical cancer. ...

Hopkins researchers discover how brain protein might control memory

...eing aware of 3-D space. In people, Arc may be one culprit behind certain long-term memory-based behaviors like drug addiction, the researchers say. "We think Arc controls how brain cells learn and associate behaviors and remember them over a long period of time," says Paul F. Worley, M.D., professor of ...

Leading reason for corneal transplants comes into focus

...us is putting us in the right neighborhood to find culprit genes," says Gottsch. "Now we have to start knocking on every door." Gottsch is heartened by success with earlier Fuchs gene-hunting studies. The Hopkins group tracked down its first FCD-related gene in a Virginia family with multiple, early onset...

Cell death following blood 'reflow' injury tracked to natural toxin

...ogy. To establish that PAR-polymer is indeed the culprit in the kind of reperfusion injuries long linked to heart attacks, strokes and a variety of blood vessel injuries, the researchers pumped mouse nerve cells full of PAR-polymer. The cells died, but to be sure PAR-polymer (and not something else) killed...

Scientists tie several cancers to common 'oncogene engine'

...he longer term, the focus is on targeting the real culprit ?and that is the MiT transcription factors or their targets. There is lots of excitement, and I believe that is the way to really nail these tumors." ...

How bad is malaria anemia? It may depend on your genes

...people worldwide who die each year of malaria. The culprit is a protein cells make in response to inflammation called MIF, which appears to suppress red blood cell production in people whose red blood cells already are infected by malaria parasites. The parasite that causes malaria - known as plasmodium -...

Infected for life

...all RNA molecule, called a microRNA (miRNA) as the culprit that keeps the latent virus-infected cell alive. These findings could one day lead to a new way to fight the virus and offers the first target for intervention in the latent infection. A research team led by Nigel W. Fraser, PhD, Professor of Microb...

Study finds that a woman's chances of having twins can be modified by diet

...ces on twinning in the journal's May 6 issue. The culprit may be insulin-like growth factor (IGF), a protein that is released from the liver of animals -- including humans -- in response to growth hormone, circulates in the blood and makes its way into the animal's milk. IGF increases the sensitivity of the...

Nutrition a major factor in rise in twin pregnancies

The commonly held view that IVF is the only culprit in the steady increase in the numbers of twins born over the past thirty years was challenged by a scientist speaking at the 22nd annual conference of the European Society of Human Reproduction and Embryology in Prague, Czech Republic, Wednesday 21 J...

'Dead zone' summer killed billions of ocean state mussels

...'s Narragansett Bay during the summer of 2001. The culprit was hypoxia, or oxygen depletion, which literally suffocates sea life. While some evidence of this "dead zone" could be seen on the bay's surface, Brown University ecologists went underwater and discovered a massive mussel die-off. In a survey of ni...

Bone and cartilage growth to blame for heart valve disease

...ing cause of atrial fibrillation, which is a major culprit in strokes and heart failure. Aortic valve disease can lead to heart failure, arrhythmia, infections in the heart, and sudden death may occur in 15 to 20 percent of people who have symptoms. Dr. Rajamannan has focused her research for the past seve...

Dogs keep dying: Many owners unaware of toxic dog food

...t at Cornell who first identified aflatoxin as the culprit in the recent wave of deaths. Trying to save dogs Over the recent holiday weeks, Center and her staff worked around-the-clock to try to save the 17 poisoned dogs admitted to Cornell's Hospital for Animals. "I've been working with liver disease i...

Single microRNA causes cancer in transgenic mouse

...spected that a particular miRNA, miR155, was a key culprit in some forms of malignant growth. He and his colleagues have been mapping the activity of dozens of miRNAs in various types of normal and malignant tissues for several years. Earlier studies showed that miR155 was unusually active in some types of l...

Scientists discover basic defect in cystic fibrosis airway glands

... that loss of CFTR-mediated fluid secretion is the culprit in cystic fibrosis. "We previously showed that cystic fibrosis airway glands have defective gland secretion in response to certain drugs," explains Joo. "The results of our present study provide evidence that the defective cystic fibrosis gland sec...

Scientists show how thinking can harm brain cells

...ty of Rochester Medical Center have targeted a new culprit and method of attack on neurologic functions in diseases such as Alzheimer's and dementia associated with HIV. In an article in the Nov. 1 issue of The Journal of Clinical Investigation, the Rochester scientists describe a new mechanism by which bra...

Gene increases risk of tuberculosis

...d. Flores-Villanueva and colleagues show that the culprit behind the increased susceptibility to TB was a small change in the gene that encodes a protein called MCP-1 (the MCP-1 gene resides of chromosome 17). The genetic change was a tiny one, with the DNA sequence differing by only a single nucleotide (t...

Anti-cancer drugs may hold promise for premature aging disorder

... stick to the inner nuclear membrane is indeed the culprit in nuclear blebbing and the root of the progeria defect, Capell and his colleagues reasoned that they could prevent these defects by blocking farnesylation of progerin. The researchers' hunch proved correct. When they changed one amino acid within ...

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