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Tag: "crystals" at biology news

Elusive HIV shape change revealed; Key clue to how virus infects cells

...to form good crystals. "Without very well-ordered crystals you get a very blurry picture," explains Harrison. "It took a very long time, and lots of computational work, to get that picture to sharpen up enough to get an answer." One of the lab's first steps will be to determine which shape of gp120 ?bound t...

Nano-Probes Allow an Inside Look at Cell Nuclei

...r who helped pioneer the development of nano-sized crystals of semiconductor materials. Called quantum dots, these microscopic crystals have shown promise in such wide-ranging applications as solar cells, computer design, and biology. I...

Researchers make gains in understanding antibiotic resistance

...ique, intense beams of x-rays are directed through crystals of proteins. The underlying atomic structure of the proteins is deduced by analyzing the pattern of diffraction of the x-rays. Steitz's group used ribosomal subunits from the primitive archaebacterium Haloarcula marismortui (Hma), which is found in ...

Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment

...e the cells are large. When the egg is thawed, ice crystals cause damage that prevents the egg from being fert...tion from liquid to solid is instantaneous. No ice crystals form and the consistency resembles a viscous glassy state. Research so far has used mouse oocytes bu...

Fundamental discovery -- Bone fracture

...of these collagen fibrils coated with tiny mineral crystals only a few atoms thick. What we found is that there is a glue in bone that holds these mineralized collagen fibrils together, and this glue works along the same principles that our interdisciplinary research group found in abalone shells. This glue i...

Virginia Tech, Nanjing Institute researchers discover half-billion year-old fossils

... and his colleagues carefully examined the calcite crystals that replicate the tubes. They believe that the crystals were emplaced shortly after the death, burial, and decay of the Ediacara organisms, thus replicating...

Nanotubes inspire new technique for healing broken bones

...not sufficient, since the growth of hydroxyapatite crystals relies on the ability of the scaffold to attract calcium ions and initiate the crystallization process. So the researchers carefully designed nanotubes with several chemical groups attached. Some of these groups assist the growth and orientation of h...

Learning how SARS spikes its quarry

...tories could concentrate their efforts on creating crystals of the relevant fragments of the spike protein in ...ter they had crystallized the protein complex, the crystals were then subjected to structural analysis using x-ray crystallography. In this widely used techniqu...

Israeli scientists successfully transplant frozen-thawed ovaries in sheep

...allows precise control over the propagation of ice crystals during the freezing process, thus reducing the damage caused to cells by conventional methods[4]. Sheep were chosen because their ovaries are similar to those of humans. The technique worked ?the frozen-thawed ovaries produced comparable numbers of f...

Metal-containing compounds show promise as HIV weapon

...process called X-ray crystallography, in which the crystals are bombarded with X-rays, and then the patterns made when the component atoms deflect the rays are deciphered. The metallacarboranes appeared to occupy the portion of the protease used to hold key proteins in place as part of the infective cycle o...

Method slashes quantum dot costs by 80 percent

...m dots by about 80 percent. Quantum dots are tiny crystals of semiconducting materials - cadmium selenide or ...rom the red to the blue end of the spectrum as the crystals get smaller. The reproducible synthesis of high-quality quantum dots became a reality in the early...

The right drug at the right time

...m dots by about 80 percent. Quantum dots are tiny crystals of semiconducting materials - cadmium selenide or ...rom the red to the blue end of the spectrum as the crystals get smaller. The reproducible synthesis of high-quality quantum dots became a reality in the early...

Bacteria which sense the Earth's magnetic field

...owth conditions. The magnetosomes are made of tiny crystals of the magnetic iron mineral magnetite (Fe3O4) -- ...ings and, from it, produce special iron oxide. The crystals also have to have a exactly defined number, form, and size, in order to be effective magnetic field ...

Zooming in on the protein-conducting channel

...crystallography, an x-ray beam is directed through crystals of a target protein. As the x-rays pass through the crystal, they are diffracted. Researchers can then analyze the diffraction pattern to determine the atomic structure of the protein. The analysis by Frank and his colleagues revealed that each chan...

New nanosensor uses quantum dots to detect DNA

...ts as a DNA sensor," Wang said. Quantum dots are crystals of semiconductor material, whose sizes are only in the range of a few nanometers across. (A nanometer is one-billionth of a meter.) They are traditionally used in electronic circuitry. In recent years, however, scientists have begun to explore their ...

Waking a sleeping virus

...ip with the neighbouring institutes, they obtained crystals of ZEBRA. Examining these crystals with high-intensity X-rays at the European Synchrotron Radiation Facility (ESRF) in Grenoble, the sc...

Thin tough skin, slow-growing gills protect larval Antarctic fish

...dults, we find ice in their bodies but these small crystals don't grow because of antifreeze proteins. Finding that larval fish don't have enough antifreeze really threw off how we understand survival in fish." While the larvae of one species, the bald notothen, survives using high levels of AFPs like the ad...

Molecule does more than slice and dice RNA

...er, Doudna noted, was a technical challenge as the crystals are small. But she said that the work was facilitated by access to the HHMI-supported crystallography beam lines at the Lawrence Berkeley National Laboratory's Advanced Light Source. The synchrotron at the Advanced Light Source is capable of generati...

Advanced genomics and proteomics improve the diagnosis and treatment of a deadly lung disease

...er, Doudna noted, was a technical challenge as the crystals are small. But she said that the work was facilitated by access to the HHMI-supported crystallography beam lines at the Lawrence Berkeley National Laboratory's Advanced Light Source. The synchrotron at the Advanced Light Source is capable of generati...

Key heart and Alzheimer's disease protein imaged for first time in native state

...ule by analyzing the x-ray diffraction patterns of crystals that make up the molecule. "The next step is higher resolution, going from the current 10 angstroms to 3.5 or better," adds Weisgraber, who is also a professor of pathology at the University of California, San Francisco. Lipid-bound proteins cha...

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