Leukemia drug turns mini-molecules up, cancer genes down
...re stage. The immature cells accumulate until they crowd out healthy white cells in the blood and bone marrow. "Our findings suggest that these three miRNAs help re-program the malignant cells to a more normal state," Garzon says, "and that they are also important for normal differentiation." In th...Action video games sharpen vision 20 percent
...ey could discern the orientation of a "T" within a crowd of other distracting symbols—a sort of electronic eye chart. Students were then divided into two groups. The experimental group played Unreal Tournament, a first-person shoot-'em-up action game, for roughly an hour a day. The control group played Tet...Study finds surfing safer than soccer
...surfers are often trying to catch waves in a dense crowd of surfers of varying abilities," says Nathanson. The authors note that although age and gender had no bearing on the injury rate, wave size and bottom type, independently, were significantly associated with a great chance of injury. "It would ...Trusting your instincts leads you to the right answer
...s to pick out unique and distinctive features in a crowd ?such as colour or orientation. Soon after our eyes have fixed on a target, the conscious or top-down part of cognition engages and examines whether the candidate really is the target or not. If the target is not distinctive enough in the 'eyes' of t...1/3 of sexually active older adults with HIV/AIDs has unprotected sex
...e in a relationship. AIDs cases among the over-50 crowd reached 90,000 in 2003. According to the Centers for Disease Control and Prevention, they will account for half of all HIV/AIDS cases in the United States by 2015 because medical intervention has extended the lifespan of those infected with HIV. Addi......l expressions of different types are detected in a crowd of neutral faces, researchers have demonstrated that male angry faces are a priority for visual processing ?particularly for male observers. The findings are reported by Mark Williams of the Massachusetts Institute of Technology and Jason Mattingley ...Rehydrate -- your RNA needs it
...f that network. The network acts like a jostling crowd at a cocktail party, where hydrogen bonds---weak, electrostatic attractions between molecules or parts of molecules---take the place of handshakes. Water molecules trapped in ribozymes can form hydrogen bonds with other water molecules or with parts ...Attacking cancer's sweet tooth is effective strategy against tumors
...y at Harvard University. As a tumor grows, cells crowd one another and may be cut off from oxygen-carrying blood vessels--a distinct disadvantage since most cells require oxygen to produce the bulk of their energy-storing adenosine triphosphate (ATP). In the 1920s, Otto Warburg proposed that some cancer ...Biomarkers may hone anti-aging therapies
...mise to remove wrinkles and other effects of aging crowd cosmetics aisle shelves, but do these treatments really work? Vanderbilt University Medical Center investigators have identified new molecular indicators -- or "biomarkers" -- of aging in the skin that could be used to evaluate anti-aging therapies....Chemical guidance of T cells leads to immunologic memory and long-term immunity
...ping to run into each other by chance, the drivers crowd around the arrival gates and hold up signs that the passengers can read from a distance. Moreover, CD8+ T cells are chemically attracted to the cells that might activate them by the chemokines these other cells produce. Dr. Germain and his colleagu...Say what? Bacterial conversation stoppers
While a chattering crowd of various species of bacteria is essentially a microbial tower of Babel, certain snippets of their chemical conversation are almost universally understood. HHMI researchers have found that bacteria of different species can talk to each other using a...TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas
... cells (B lymphocytes) multiply uncontrollably and crowd out other blood cells. The St. Jude researchers report that TEL2 cooperates with MYC to increase the chance that a certain mutation will occur in precancerous B lymphocytes, permitting these cells to become cancerous. This mutation inactivates the fu...